Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yohei Kobashi"'
Analysis of the Policy Network for the 'Feed-in Tariff Law' in Japan: Evidence from the GEPON Survey
Publikováno v:
Journal of Contemporary Eastern Asia, Vol 15, Iss 1, Pp 41-63 (2016)
Energy policy is known to have higher path dependency among policy fields (Kuper and van Soest, 2003; OECD, 2012; Kikkawa, 2013) and is a critical component of the infrastructure development undertaken in the early stages of nation building. Actor ro
Externí odkaz:
https://doaj.org/article/adfcca776885424482a80cac7975a0bc
Autor:
Madoka Kawamura, Yohei Kobashi, Hiroaki Tanaka, Ayako Bohno-Mikami, Makoto Hamada, Yuji Ito, Takashi Hirata, Hiroki Ohara, Naoki Kojima, Hiroko Koretsune, Emi Gunji, Takuya Fukunaga, Shoko Inatani, Yoshitaka Hasegawa, Akinori Suzuki, Teisuke Takahashi, Hiroyuki Kakinuma
Publikováno v:
Journal of Medicinal Chemistry. 65:14599-14613
20-Hydroxyeicosatetraenoic acid (20-HETE) is one of the major oxidized arachidonic acid (AA) metabolites produced by cytochrome P450 (CYP) 4A11 and CYP4F2 isozymes in the human liver and kidney. Numerous studies have suggested the involvement of 20-H
Publikováno v:
VOLUNTAS: International Journal of Voluntary and Nonprofit Organizations. 32:534-547
This study innovates by introducing a conceptual distinction between the provision of public services and the receipt of government funding. The study also provides empirical analysis to show that public service provision, independent of government f
Publikováno v:
Journal of Economic Dynamics and Control. 100:230-250
We conduct a discourse analysis of the Bank of Japan’s Monthly Report and examine its characteristics in relation to business cycles. We find that ambiguous expressions tend to appear more frequently with negative expressions, and this tendency is
Autor:
Mami Sugisaki-Kitano, Takahiro Oi, Lisa Okumura-Kitajima, Fumiyasu Shiozawa, Yohei Kobashi, Kuroda Shoichi, Koji Yamamoto, Kenichi Kawabe, Fusayo Io, Hiroyuki Kakinuma
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:394-409
A new series of C-phenyl d -glucitol derivatives was designed and synthesized, and their SGLT1 inhibitory potency and absorbability were evaluated. We also investigated whether kidney drug retention could be avoided by creating molecules with differe
Autor:
Hiroyuki Kakinuma, Yuki Shimizu, Kayo Kimura, Yohei Kobashi, Lisa Okumura-Kitajima, Makoto Hamada, Koji Yamamoto, Hiroko Koretsune, Kuroda Shoichi, Kenichi Kawabe, Fumiyasu Shiozawa, Madoka Kawamura
Publikováno v:
Chemicalpharmaceutical bulletin. 68(7)
Sodium-glucose cotransporter 1 (SGLT1) is the primary transporter for glucose absorption from the gastrointestinal tract. While C-phenyl D-glucitol derivative SGL5213 has been reported to be a potent intestinal SGLT1 inhibitor for use in the treatmen
Autor:
Norikazu Ohtake, Keiko Fusegi, Fumiyasu Shiozawa, Masako Miyoshi, Madoka Kawamura, Matsuda Daisuke, Kayo Kimura, Hiroyuki Kakinuma, Youichirou Suga, Noriko Takayama, Shinichi Nishimoto, Yohei Kobashi
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:1832-1847
The design and synthesis of a novel class of 7-azaspiro[3.5]nonane GPR119 agonists are described. In this series, optimization of the right piperidine N-capping group (R2) and the left aryl group (R3) led to the identification of compound 54g as a po
Autor:
Madoka Kawamura, Masako Miyoshi, Fumiyasu Shiozawa, Yohei Kobashi, Kayo Kimura, Shinichi Nishimoto, Hiroyuki Kakinuma, Kenichi Kawabe, Matsuda Daisuke, Ayako Mikami, Koji Oda, Noriko Takayama, Makoto Hamada, Norikazu Ohtake
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:3441-3446
Design and synthesis of a novel class of 1H-pyrazolo[3,4-c]pyridine GPR119 receptor agonists are described. Lead compound 4 was identified through the ligand-based drug design approach. Modification of the left-hand aryl group (R(1)) and right-hand p
Analysis of the Policy Network for the 'Feed-in Tariff Law' in Japan: Evidence from the GEPON Survey
Publikováno v:
Journal of Contemporary Eastern Asia, Vol 15, Iss 1, Pp 41-63 (2016)
Energy policy is known to have higher path dependency among policy fields (Kuper and van Soest, 2003; OECD, 2012; Kikkawa, 2013) and is a critical component of the infrastructure development undertaken in the early stages of nation building. Actor ro
Autor:
Lisa Okumura-Kitajima, Yohei Kobashi, Kuroda Shoichi, Fusayo Io, Takahiro Oi, Koji Yamamto, Hiroyuki Kakinuma, Hideaki Amada
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(22)
The design and synthesis of a novel class of low-absorbable SGLT1 inhibitors are described. To achieve low absorption in the new series, we performed an optimization study based on a strategy to increase TPSA. Fortunately, the optimization of an agly