Výsledky vyhledávání - "Yohei, Kuroda"

Hyperinsulinemia and Insulin Receptor Gene Mutation in Nonobese Healthy Subjects in Japan

Autor: Takehiko Watanabe, Junji Kozawa, Hiromi Iwahashi, Akihisa Imagawa, Iichiro Shimomura, Yohei Kuroda, Ryuya Iwamoto, Yuya Yamada, Shingo Fujita, Kenji Fukui

Publikováno v: Journal of the Endocrine Society

Context: Hyperinsulinemia is often observed in obese people, owing to their insulin resistance accompanied by visceral fat accumulation, but the frequency of hyperinsulinemia in nonobese people is not well known. Mutations in the insulin receptor gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92b2bae6eac18f4d971e77d29b5aeb0
https://doi.org/10.1210/js.2017-00332

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Hyperinsulinemic hypoglycemia syndrome associated with mutations in the human insulin receptor gene: Report of two cases

Autor: Iichiro Shimomura, Yohei Kuroda, Kenji Fukui, Hiromi Iwahashi, Akihisa Imagawa, Ikuo Mineo, Atsunori Fukuhara, Ryuya Iwamoto

Publikováno v: Endocrine Journal. 62:353-362

Insulinoma and insulin or insulin receptor (IR) autoantibodies are the main causes of hyperinsulinemic hypoglycemia in adults, but the exact cause in other cases remains obscure. This study is to determine the genetic basis of hyperinsulinemic hypogl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe622701046277ce607d9e95efa6b953
https://doi.org/10.1507/endocrj.ej14-0547

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A Novel Mutation in the type Iα Regulatory Subunit of Protein Kinase A (PRKAR1A) in a Cushing's Syndrome Patient with Primary Pigmented Nodular Adrenocortical Disease

Autor: Sachiko Tamba, Yuji Matsuzawa, Ryohei Mineo, Akiko Furuya, Yohei Kuroda, Tokuo Mukai, Kenji Saisho, Takashi Maekawa, Tomonori Okita, Yasuhiro Nakamura, Mitsuaki Kyo, Reiko Mori, Koji Yamamoto, Hironobu Sasano, Yusuke Kawachi, Yuya Yamada

Publikováno v: Internal medicine (Tokyo, Japan). 55(17)

A 40-year-old man presented with Cushing's syndrome due to bilateral adrenal hyperplasia with multiple nodules. Computed tomography scan results were atypical demonstrating an enlargement of the bilateral adrenal glands harboring multiple small nodul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34c95dd18c265347aec6a776b12cbc4
https://pubmed.ncbi.nlm.nih.gov/27580546

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Carotid intima-media thickness, but not visceral fat area or adiponectin, correlates with intracoronary stenosis detected by multislice computed tomography in people with type 2 diabetes and hypertension

Autor: Tadashi Nakamura, Yohei Kuroda, Tohru Funahashi, Iichiro Shimomura, Masahiro Kumada, Keita Yamasaki, Kenichi Tsujii, Yasuhiko Nakagawa, Satoru Sumitsuji, Kouichi Tachibana, Hideaki Nakatsuji, Yuhei Nojima, Yukiyoshi Okauchi, Tomoko Nakanishi-Minami, Ken Kishida

Publikováno v: Diabetes Research and Clinical Practice. 95:e23-e26

We investigated the relationship between intracoronary stenosis detected by multislice computed tomography and various clinical parameters in type 2 diabetic patients with hypertension treated with candesartan ( n =42). The results showed that caroti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155fe5fe4294a869e8f61218a2738461
https://doi.org/10.1016/j.diabres.2011.10.022

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Interferon stimulated gene 15 has an anti-apoptotic effect on MIN6 cells

Autor: Taka-aki Matsuoka, Yoshifumi Sato, Yugo Miyata, Yohei Kuroda, Hideaki Kaneto, Atsushi Yoshikawa, Toshiaki Hanafusa, Kenji Fukui, Hiromi Iwahashi, Shinsuke Nakata, Akihisa Imagawa, Iichiro Shimomura

Publikováno v: Endocrine journal. 61(9)

Type 1 diabetes, one of two major forms of diabetes, results from the complete destruction of pancreatic beta cells. Viral infection has been suggested to be a trigger of beta cell destruction, the pathogenesis of type 1 diabetes. The aim of this stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd3d83d71ed5d29186376af8a026c5e
https://pubmed.ncbi.nlm.nih.gov/25031023

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Reciprocal regulation of natriuretic peptide receptors by insulin in adipose cells

Autor: Tohru Funahashi, Yohei Kuroda, Norikazu Maeda, Toshiyuki Hibuse, Ayumu Hirata, Ken Kishida, Iichiro Shimomura, Hideaki Nakatsuji, Shinji Kihara, Aki Hiuge

Publikováno v: Biochemical and biophysical research communications. 392(1)

Atrial- and brain-type natriuretic peptides (ANP and BNP, respectively) have been shown to exert potent lipolytic action in adipocytes. A family of natriuretic peptide receptors (NPRs), NPR-1, NPR-2, and NPR-3, mediates their physiologic effects. NPR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7e59affa2a6b75de73f338a23fd0b7
https://pubmed.ncbi.nlm.nih.gov/20059960

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URB is abundantly expressed in adipose tissue and dysregulated in obesity

Autor: Akifumi Kurata, Iichiro Shimomura, Tohru Hadama, Shinji Kihara, Tohru Funahashi, Atsutaka Yasui, Toshiyuki Hibuse, Suguru Akamatsu, Sachiko Tamba, Hitoshi Nishizawa, Yohei Kuroda, Norikazu Maeda, Takuya Okada, Kazuki Tobita, Mina Sonoda, Kazuhisa Maeda

Publikováno v: Biochemical and biophysical research communications. 367(2)

Dysregulated production of adipocytokines in obesity is involved in the development of metabolic syndrome. URB/DRO1 contains N-terminal signal sequence and is thought to play a role in apoptosis of tumor cells. In the present study, we investigated t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79304f0bdde9498c7b06618af9c9dc32
https://pubmed.ncbi.nlm.nih.gov/18178152

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