Zobrazeno 1 - 10 of 84 pro vyhledávání: '"Yohei, Hirai"'
1
Akademický článek
PRSS3/mesotrypsin as a putative regulator of the biophysical characteristics of epidermal keratinocytes in superficial layers
Autor: Moeko Kida, Junya Abe, Haruna Hori, Yohei Hirai
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Mesotrypsin, encoded by the PRSS3 gene, is a distinctive trypsin isoform renowned for its exceptional resistance to traditional trypsin inhibitors and unique substrate specificity. Within the skin epidermis, this protein primarily expresses
Externí odkaz: https://doaj.org/article/4695aeb780f744fb95053322ef79d023
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2
Akademický článek
Suppression of P-cadherin expression as a key regulatory element for embryonic stem cell stemness
Autor: Yuka Takeda, Shuji Matsuguchi, Sae Nozaki, Taisei Mihara, Junya Abe, Yohei Hirai
Publikováno v: Cell Structure and Function, Vol 48, Iss 1, Pp 49-57 (2022)
In embryonic stem (ES) cell colonies, a small subpopulation that changes cell shape and loses pluripotency often appears in two-dimensional (2D) cultures, even in the presence of a stemness factor. We have previously shown that membrane translocation
Externí odkaz: https://doaj.org/article/e6bb222ef11e40ad86197631fac07144
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3
Akademický článek
Generation of iPS-derived model cells for analyses of hair shaft differentiation
Autor: Takumi Kido, Tomoatsu Horigome, Minori Uda, Naoki Adachi, Yohei Hirai
Publikováno v: BioTechniques, Vol 63, Iss 3, Pp 131-134 (2017)
Biological evaluation of hair growth/differentiation activity in vitro has been a formidable challenge, primarily due to the lack of relevant model cell systems. To solve this problem, we generated a stable model cell line in which successive differe
Externí odkaz: https://doaj.org/article/29e8e1f4c61548c5893dc0130718ee3d
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9
Akademický článek
A newly established culture method highlights regulatory roles of retinoic acid on morphogenesis and calcification of mammalian limb cartilage
Autor: Eizo Masuda, Kota Shirai, Kenji Maekubo, Yohei Hirai
Publikováno v: BioTechniques, Vol 58, Iss 6, Pp 318-324 (2015)
During mammalian embryogenesis, sclerotome-derived chondrocytes in the limb bud are arranged into a complicated bone shape with specific areas undergoing hypertrophy and calcification, creating a region-specific mineralized pattern in the cartilage.
Externí odkaz: https://doaj.org/article/57810501eed94fdc9281e3d0ea5387cd
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10
Extracellular epimorphin impairs expression and processing of profilaggrin in HaCaT keratinocytes
Autor: Haruna Hori, Ayaka Kotani, Junya Abe, Shuji Matsuguchi, Yohei Hirai
The expression and processing of filaggrin, a filament-associated protein in the skin epidermis, is closely associated with keratinocyte cornification. The large precursor profilaggrin (Pro-FLG) is initially detected at the granular layer in keratohy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7905fa509a0767c7aba1589f63551a
https://doi.org/10.21203/rs.3.rs-1706695/v1
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