Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Yohan Yee"'
Publikováno v:
NeuroImage, Vol 285, Iss , Pp 120453- (2024)
For information from sensory organs to be processed by the brain, it is usually passed to appropriate areas of the cerebral cortex. Almost all of this information passes through the thalamus, a relay structure that reciprocally connects to the vast m
Externí odkaz:
https://doaj.org/article/8257cf0fe74a413d8e62cd3ce9acd5ac
Publikováno v:
eLife, Vol 11 (2022)
The ever-increasing use of mouse models in preclinical neuroscience research calls for an improvement in the methods used to translate findings between mouse and human brains. Previously, we showed that the brains of primates can be compared in a dir
Externí odkaz:
https://doaj.org/article/419b7b023e1444cb84adf0bb12357ae6
Autor:
Zsuzsa Lindenmaier, Jacob Ellegood, Monique Stuive, Kaitlyn Easson, Yohan Yee, Darren Fernandes, Jane Foster, Evdokia Anagnostou, Jason P. Lerch
Publikováno v:
NeuroImage, Vol 257, Iss , Pp 119243- (2022)
Although initially showing great potential, oxytocin treatment has encountered a translational hurdle in its promise of treating the social deficits of autism. Some debate surrounds the ability of oxytocin to successfully enter the brain, and therefo
Externí odkaz:
https://doaj.org/article/95fe065d86e04c59bae0dee97876a494
Autor:
Darren J. Fernandes, Shoshana Spring, Anna R. Roy, Lily R. Qiu, Yohan Yee, Brian J. Nieman, Jason P. Lerch, Mark R. Palmert
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Maternal environmental exposures, such as high-fat diets, diabetes and obesity, can induce long-term effects in offspring. These effects include increased risk of neurodevelopmental disorders (NDDs) including autism spectrum disorder (ASD),
Externí odkaz:
https://doaj.org/article/d97b5868a8fe46028363b423214433bb
Autor:
Anum Rahman, Taylor DeYoung, Lindsay S. Cahill, Yohan Yee, Sarah K. Debebe, Owen Botelho, Mike Seed, Rajiv R. Chaturvedi, John G. Sled
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 11 (2021)
In hypoplastic left heart syndrome (HLHS), the mechanisms leading to left heart hypoplasia and their associated fetal abnormalities are largely unknown. Current animal models have limited utility in resolving these questions as they either do not ful
Externí odkaz:
https://doaj.org/article/00f6009b077645dcb36ca642e314f5c0
Autor:
Zsuzsa Lindenmaier, Yohan Yee, Adrienne Kinman, Darren Fernandes, Jacob Ellegood, Christie L. Burton, Diane M. Robins, Armin Raznahan, Paul Arnold, Jason P. Lerch
Publikováno v:
NeuroImage, Vol 226, Iss , Pp 117594- (2021)
The androgen receptor (AR) is known for masculinization of behavior and brain. To better understand the role that AR plays, mice bearing humanized Ar genes with varying lengths of a polymorphic N-terminal glutamine (Q) tract were created (Albertelli
Externí odkaz:
https://doaj.org/article/7f424754c56a42b2bd29d962bbc2f856
Autor:
Joanes Grandjean, Carola Canella, Cynthia Anckaerts, Gülebru Ayrancı, Salma Bougacha, Thomas Bienert, David Buehlmann, Ludovico Coletta, Daniel Gallino, Natalia Gass, Clément M. Garin, Nachiket Abhay Nadkarni, Neele S. Hübner, Meltem Karatas, Yuji Komaki, Silke Kreitz, Francesca Mandino, Anna E. Mechling, Chika Sato, Katja Sauer, Disha Shah, Sandra Strobelt, Norio Takata, Isabel Wank, Tong Wu, Noriaki Yahata, Ling Yun Yeow, Yohan Yee, Ichio Aoki, M. Mallar Chakravarty, Wei-Tang Chang, Marc Dhenain, Dominik von Elverfeldt, Laura-Adela Harsan, Andreas Hess, Tianzi Jiang, Georgios A. Keliris, Jason P. Lerch, Andreas Meyer-Lindenberg, Hideyuki Okano, Markus Rudin, Alexander Sartorius, Annemie Van der Linden, Marleen Verhoye, Wolfgang Weber-Fahr, Nicole Wenderoth, Valerio Zerbi, Alessandro Gozzi
Publikováno v:
NeuroImage, Vol 205, Iss , Pp 116278- (2020)
Preclinical applications of resting-state functional magnetic resonance imaging (rsfMRI) offer the possibility to non-invasively probe whole-brain network dynamics and to investigate the determinants of altered network signatures observed in human st
Externí odkaz:
https://doaj.org/article/c0f102b5e81144188c9903975357a3a8
Autor:
Jacob Ellegood, Yohan Yee, Travis M. Kerr, Christopher L. Muller, Randy D. Blakely, R. Mark Henkelman, Jeremy Veenstra-VanderWeele, Jason P. Lerch
Publikováno v:
Molecular Autism, Vol 9, Iss 1, Pp 1-12 (2018)
Abstract Background The serotonin (5-HT) system has long been implicated in autism spectrum disorder (ASD) as indicated by elevated whole blood and platelet 5-HT, altered platelet and brain receptor and transporter binding, and genetic linkage and as
Externí odkaz:
https://doaj.org/article/cba300387a234a9bb145d2b40bfefaf6
Autor:
Rebekah Tillotson, Keqin Yan, Julie Ruston, Taylor de Young, Alex Córdova, Valérie Turcotte- Cardin, Yohan Yee, Christine Taylor, Shagana Visuvanathan, Christian Babbs, Evgueni A Ivakine, John G Sled, Brian J Nieman, David J Picketts, Monica J Justice
Publikováno v:
Human Molecular Genetics.
ATRX is a chromatin remodelling ATPase that is involved in transcriptional regulation, DNA damage repair and heterochromatin maintenance. It has been widely studied for its role in ALT-positive cancers, but its role in neurological function remains e