Mild Neonatal Brain Hypoxia-Ischemia in Very Immature Rats Causes Long-Term Behavioral and Cerebellar Abnormalities at Adulthood

Autor: Eduardo Farias Sanches, Yohan van de Looij, Audrey Toulotte, Stéphane Vladimir Sizonenko, Hongxia Lei

Publikováno v: Frontiers in Physiology, Vol 10 (2019)

Systemic hypoxia-ischemia (HI) often occurs during preterm birth in human. HI induces injuries to hinder brain cells mainly in the ipsilateral forebrain structures. Such HI injuries may cause lifelong disturbances in the distant regions, such as the

Externí odkaz: https://doaj.org/article/d8fa78eb82764c3a97d50fa28c74d79d

The impact of short-term machine perfusion on the risk of cancer recurrence after rat liver transplantation with donors after circulatory death.

Autor: Graziano Oldani, Andrea Peloso, Florence Slits, Quentin Gex, Vaihere Delaune, Lorenzo A Orci, Yohan van de Looij, Didier J Colin, Stéphane Germain, Claudio de Vito, Laura Rubbia-Brandt, Stéphanie Lacotte, Christian Toso

Publikováno v: PLoS ONE, Vol 14, Iss 11, p e0224890 (2019)

Hypothermic and normothermic ex vivo liver perfusions promote organ recovery after donation after circulatory death (DCD). We tested whether these perfusions can reduce the risk of hepatocellular carcinoma (HCC) recurrence in a 1h-DCD syngeneic trans

Externí odkaz: https://doaj.org/article/669c7066b840442791ba1174a6afe2c7

Multimodal MRI Imaging of Apoptosis-Triggered Microstructural Alterations in the Postnatal Cerebral Cortex

Autor: Petra Susan Hüppi, Yohan van de Looij, Volodymyr Petrenko, Jevgenia Mihhailova, Patrick Salmon, Stéphane Sizonenko, Jozsef Zoltan Kiss

Publikováno v: Cerebral Cortex (2017) pp. 1-14

Prematurely born children often develop neurodevelopmental delay that has been correlated with reduced growth and microstructural alterations in the cerebral cortex. Much research has focused on apoptotic neuronal cell death as a key neuropathologica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca145927235e8cca649a07728e619de8
http://doc.rero.ch/record/331503/files/CERCOR_28_3_949.pdf

Multi-modal assessment of long-term erythropoietin treatment after neonatal hypoxic-ischemic injury in rat brain.

Autor: Yohan van de Looij, Alexandra Chatagner, Charles Quairiaux, Rolf Gruetter, Petra S Hüppi, Stéphane V Sizonenko

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e95643 (2014)

Erythropoietin (EPO) has been recognized as a neuroprotective agent. In animal models of neonatal brain injury, exogenous EPO has been shown to reduce lesion size, improve structure and function. Experimental studies have focused on short course trea

Externí odkaz: https://doaj.org/article/7a86f4bef80e4c3dadf9150ce53f8257

Magnetic Resonance Imaging Correlates of White Matter Gliosis and Injury in Preterm Fetal Sheep Exposed to Progressive Systemic Inflammation

Autor: Laura Bennet, Kyohei Yamaguchi, Natasha Mitchell, Joanne O. Davidson, Justin M. Dean, Alistair J. Gunn, Guido Wassink, Sharmony B. Kelly, Christopher A. Lear, Valerie A. Zahra, Yohan van de Looij, Simerdeep K Dhillon, Robert Galinsky, Victoria J King, Stéphane Sizonenko, Fraser Nott

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol. 21, No 23 (2020) P. 8891
International Journal of Molecular Sciences, Vol 21, Iss 8891, p 8891 (2020)

Progressive fetal infection/inflammation is strongly associated with neural injury after preterm birth. We aimed to test the hypotheses that progressively developing fetal inflammation leads to neuroinflammation and impaired white matter development

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778ec7715b73085361018cf21df474eb