Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yoh-ichi Seki"'
Autor:
Katsuhiko Hayashi, Akihiko Yoshimura, Naoko Nagata, Hiromasa Inoue, Kunisuke Himeno, Tadahilo Oshida, Kyoko Inagaki-Ohara, James A. Johnston, Masato Kubo, Hirohisa Saito, Anne O'Garra, Koichiro Matsumoto, Shinjiro Hamano, Yoh Ichi Seki, Nicholas A. Cacalano, Okiru Komine, Satoru Fukuyama
Publikováno v:
Nature Medicine. 9:1047-1054
Members of the suppressor of cytokine signaling (SOCS) family are involved in the pathogenesis of many inflammatory diseases. SOCS-3 is predominantly expressed in T-helper type 2 (T(H)2) cells, but its role in T(H)2-related allergic diseases remains
Autor:
Ryosuke Watanabe, Yoh Ichi Seki, Akihiko Yoshimura, Akira Matsumoto, Masato Kubo, James A. Johnston, Ryo Abe, Katsuhiko Hayashi, Yohsuke Harada
Publikováno v:
The Journal of Experimental Medicine
Suppressor of cytokine signaling (SOCS)3 has been characterized as a negative feedback regulator in cytokine-mediated Janus kinase signal transducer and activator of transcription signaling. However, this study shows that T cells from transgenic mice
Autor:
Akira Matsumoto, Noriyasu Seki, Tadamitsu Kishimoto, Masato Kubo, J T Ransom, Akihiko Yoshimura, Jun Tsukada, Tetsuji Naka, Yoh Ichi Seki, Katsuhiko Hayashi
Publikováno v:
Proceedings of the National Academy of Sciences. 99:13003-13008
The development of helper T (Th) cell subsets, which secrete distinct cytokines, plays an important role in determining the type of immune response. The IL-4-mediated Janus kinase–signal transducer and activator of transcription signaling pathway i
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 175(8)
Allergic conjunctivitis (AC) is a common allergic eye disease characterized by clinical symptoms such as itchiness, conjunctival congestion, elevated Ag-specific IgE, mast cell activation, and local eosinophil infiltration. In this study we establish
Autor:
Yuji Sugita, Tadahilo Oshida, Akira Akasawa, Naoko Nagata, Yoh-ichi Seki, Gozoh Tsujimoto, Hirohisa Saito, Tohru Arai, Masato Kubo, Ning Lu Yoshida
Publikováno v:
Allergology International. (2):273-282
Background Differential gene expression in CD3+ T cells from allergic patients stimulated with allergen will provide important information on the responses of T cells. Methods After stimulation of peripheral blood mononuclear cells (PBMCs) with mite