Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Yogita Ghodke‐Puranik"'
Autor:
Yogita Ghodke-Puranik, Zhongbo Jin, Kip D. Zimmerman, Hannah C. Ainsworth, Wei Fan, Mark A. Jensen, Jessica M. Dorschner, Danielle M. Vsetecka, Shreyasee Amin, Ashima Makol, Floranne Ernste, Thomas Osborn, Kevin Moder, Vaidehi Chowdhary, Carl D. Langefeld, Timothy B. Niewold
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-10 (2021)
Abstract Background We performed expression quantitative trait locus (eQTL) analysis in single classical (CL) and non-classical (NCL) monocytes from patients with systemic lupus erythematosus (SLE) to quantify the impact of well-established genetic r
Externí odkaz:
https://doaj.org/article/96e352fc33f345cd81032036828010a0
Autor:
Uma Thanarajasingam, Anoohya N. Muppirala, Mark A. Jensen, Yogita Ghodke‐Puranik, Jessica M. Dorschner, Danielle M. Vsetecka, Shreyasee Amin, Ashima Makol, Floranne Ernste, Thomas Osborn, Kevin Moder, Vaidehi Chowdhary, Timothy B. Niewold
Publikováno v:
ACR Open Rheumatology, Vol 1, Iss 8, Pp 499-506 (2019)
Objective Type I interferon (IFN) is important to systemic lupus erythematosus (SLE) pathogenesis, but it is not clear how chronic elevations in IFN alter immune function. We compared cytokine responses after whole blood stimulation with Toll‐like
Externí odkaz:
https://doaj.org/article/14b5a31df0c8437ca5e94ef2ebb4a103
Autor:
Theresa L. Wampler Muskardin, Wei Fan, Zhongbo Jin, Mark A. Jensen, Jessica M. Dorschner, Yogita Ghodke-Puranik, Betty Dicke, Danielle Vsetecka, Kerry Wright, Thomas Mason, Scott Persellin, Clement J. Michet, John M. Davis, Eric Matteson, Timothy B. Niewold
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Previously, we demonstrated in test and validation cohorts that type I IFN (T1IFN) activity can predict non-response to tumor necrosis factor inhibitors (TNFi) in rheumatoid arthritis (RA). In this study, we examine the biology of non-classical and c
Externí odkaz:
https://doaj.org/article/d521672247904464a02dd07ba7908c20
Autor:
Theresa Wampler Muskardin, Zhongbo Jin, Jessica M. Dorschner, Yogita Ghodke-Puranik, Timothy Niewold
Publikováno v:
Journal of Clinical and Translational Science, Vol 3, Pp 8-9 (2019)
OBJECTIVES/SPECIFIC AIMS: The cellular mechanisms that underlie the IFNβ/α ratio that predicts response are not known. Effects of IFN on single immune cells may be masked in whole blood or mixed cell populations. By studying the effect of IFNβ/α
Externí odkaz:
https://doaj.org/article/a2713f8136b949be848411cb630b5657
Autor:
Tarek H. Mouhieddine, Oliver Van Oekelen, David T. Melnekoff, Jeanne Li, Yogita Ghodke-Puranik, Guido Lancman, Santiago Thibaud, Darren Pan, Sridevi Rajeeve, Sarita Agte, Adolfo Aleman, Larysa Sanchez, Shambavi Richard, Adriana Rossi, Joshua Richter, Hearn Jay Cho, Cesar Rodriguez, Alessandro Lagana, Erin Moshier, Ajai Chari, Sundar Jagannath, Samir Parekh
Publikováno v:
Blood Advances. 7:1056-1064
T-cell redirection therapy using chimeric antigen receptor (CAR) T cells and bispecific antibodies (BiAbs) has shown promising efficacy in heavily pretreated patients with relapsed/refractory multiple myeloma (RRMM), leading to the approval of 2 CAR
Autor:
Oliver Van Oekelen, Karthik Nath, Tarek H. Mouhieddine, Tasmin Farzana, Adolfo Aleman, David T. Melnekoff, Yogita Ghodke-Puranik, Gunjan L. Shah, Alexander Lesokhin, Sergio Giralt, Santiago Thibaud, Adriana Rossi, Cesar Rodriguez, Larysa Sanchez, Joshua Richter, Shambavi Richard, Hearn J. Cho, Ajai Chari, Saad Z. Usmani, Sundar Jagannath, Urvi A. Shah, Sham Mailankody, Samir Parekh
Publikováno v:
Blood. 141:756-765
B-cell maturation antigen (BCMA)–directed chimeric antigen receptor T-cell (CAR T) therapy has demonstrated remarkable efficacy in patients with relapsed/refractory multiple myeloma, and now there are two US Food and Drug Administration–approved
Autor:
Adolfo Aleman, Ariel Kogan Zajdman, Yogita Ghodke-Puranik, Bhaskar Upadhyaya, Tarek H. Mouhieddine, Oliver Van Oekelen, Larysa Sanchez, Shambavi Richard, Adriana Rossi, Joshua Richter, Hearn J. Cho, Cesar Rodriguez, Ajai Chari, Sundar Jagannath, Samir Parekh
Publikováno v:
Blood. 140:4193-4195
Autor:
Santiago Thibaud, Md. Babu Mia, Oliver Van Oekelen, Tarek H. Mouhieddine, Christoph Schaniel, Yogita Ghodke-Puranik, Adolfo Aleman, Bhaskar Upadhyaya, Guido Lancman, Alessandro Lagana, Shambavi Richard, Adriana Rossi, Ajai Chari, Larysa Sanchez, Cesar Rodriguez, Hearn J. Cho, Joshua Richter, Ronald Hoffman, Sundar Jagannath, Samir Parekh
Publikováno v:
Blood. 140:614-616
Autor:
Oliver, Van Oekelen, Karthik, Nath, Tarek H, Mouhieddine, Tasmin, Farzana, Adolfo, Aleman, David T, Melnekoff, Yogita, Ghodke-Puranik, Gunjan L, Shah, Alexander M, Lesokhin, Sergio A, Giralt, Santiago, Thibaud, Adriana, Rossi, Cesar, Rodriguez, Larysa, Sanchez, Joshua, Richter, Shambavi, Richard, Hearn Jay, Cho, Ajai, Chari, Saad Z, Usmani, Sundar, Jagannath, Urvi A, Shah, Sham, Mailankody, Samir, Parekh
Publikováno v:
Blood.
B-cell maturation antigen (BCMA)-directed chimeric antigen receptor T cell therapy (CAR T) has demonstrated remarkable efficacy in patients with relapsed/refractory multiple myeloma, and there are now two FDA-approved BCMA-directed CAR T products. Ho
Autor:
Tarek H, Mouhieddine, Oliver, Van Oekelen, David T, Melnekoff, Jeanne, Li, Yogita, Ghodke-Puranik, Guido, Lancman, Santiago, Thibaud, Darren, Pan, Sridevi, Rajeeve, Sarita, Agte, Adolfo, Aleman, Larysa, Sanchez, Shambavi, Richard, Adriana, Rossi, Joshua, Richter, Hearn Jay, Cho, Cesar, Rodriguez, Alessandro, Lagana, Erin L, Moshier, Ajai, Chari, Sundar, Jagannath, Samir, Parekh
Publikováno v:
Blood advances.
T-cell redirection therapy with chimeric antigen receptor (CAR)-T cells and bispecific antibodies (BiAbs) has shown promising efficacy in heavily pretreated relapsed/refractory multiple myeloma (RRMM) patients, leading to the approval of two CAR-T ce