Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yogesh Sutar"'
Autor:
Raghuram Koganti, Tejabhiram Yadavalli, Yogesh Sutar, Sudipta Mallick, Abhijit Date, Deepak Shukla
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105682- (2022)
Summary: Chronic inflammation of the immune privileged cornea originating from viral or nonviral conditions results in significant vision loss. Topical corticosteroids are the common treatments for corneal inflammation, but the drugs cause serious an
Externí odkaz:
https://doaj.org/article/b952d891e3f747bd9eecb01fd851d328
Niclosamide-loaded nanoparticles disrupt Candida biofilms and protect mice from mucosal candidiasis.
Autor:
Yogesh Sutar, Sunna Nabeela, Shakti Singh, Abdullah Alqarihi, Norma Solis, Teklegiorgis Ghebremariam, Scott Filler, Ashraf S Ibrahim, Abhijit Date, Priya Uppuluri
Publikováno v:
PLoS Biology, Vol 20, Iss 8, p e3001762 (2022)
Candida albicans biofilms are a complex multilayer community of cells that are resistant to almost all classes of antifungal drugs. The bottommost layers of biofilms experience nutrient limitation where C. albicans cells are required to respire. We p
Externí odkaz:
https://doaj.org/article/e94b267c91b84c289ac21a620f30f005
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-11 (2021)
Despite strong demand for their clinical use, the synthesis of heparin oligosaccharides as anticoagulants remains challenging. Here, a mild and scalable formal synthesis of Fondaparinux pentasaccharide is presented through [Au]/[Ag]-catalyzed glycosi
Externí odkaz:
https://doaj.org/article/b6811f823d6b439d9e45f39e05dc7437
Autor:
Hiwa K. Saeed, Yogesh Sutar, Pratikkumar Patel, Roopal Bhat, Sudipta Mallick, Alyssa E. Hatada, Dana-Lynn T. Koomoa, Ingo Lange, Abhijit A. Date
Publikováno v:
ACS Omega, Vol 6, Iss 4, Pp 2626-2637 (2021)
Externí odkaz:
https://doaj.org/article/ff5bb18a6b214e9f96e2ef29257f5d64
Autor:
Aditya Josyula, Revaz Omiadze, Kunal Parikh, Pranjali Kanvinde, Matthew B. Appell, Pratikkumar Patel, Hiwa Saeed, Yogesh Sutar, Nicole Anders, Ping He, Peter J. McDonnell, Justin Hanes, Abhijit A. Date, Laura M. Ensign
Publikováno v:
Bioengineering & Translational Medicine, Vol 6, Iss 3, Pp n/a-n/a (2021)
Abstract There are numerous barriers to achieving effective intraocular drug administration, including the mucus layer protecting the ocular surface. For this reason, antibiotic eye drops must be used multiple times per day to prevent and treat ocula
Externí odkaz:
https://doaj.org/article/53f65d7dc2de46cba1cb8c3427acb669
Autor:
Yogesh Sutar, Tejabhiram Yadavalli, Sagar Kumar Paul, Sudipta Mallick, Raghuram Koganti, Harsh Chauhan, Abhijit A. Date, Deepak Shukla
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1920 (2021)
BX795 is a TANK binding kinase-1 inhibitor that has shown excellent therapeutic activity in murine models of genital and ocular herpes infections on topical delivery. Currently, only the BX795 free base and its hydrochloride salt are available commer
Externí odkaz:
https://doaj.org/article/aad4ca5d6d6d442fa8106e42d563df16
Publikováno v:
Chemical Communications. 58:641-644
Unlike solid phase synthesis of peptides, synthesis of oligosaccharides by solid phase methods is lagging behind owing to inherent challenges faced while executing glycosidations. In this communication, silver-assisted gold-catalyzed glycosidations a
Autor:
Yogesh Sutar, Sunna Nabeela, Shakti Singh, Abdullah Alqarihi, Norma Solis, Teklegiorgis Ghebremariam, Scott Filler, Ashraf S. Ibrahim, Abhijit Date, Priya Uppuluri
Candida albicans biofilms are a complex multilayer community of cells that are resistant to almost all classes of antifungal drugs. The bottommost layers of biofilms experience nutrient limitation where C. albicans cells are required to respire. We p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f76636b4697fea0848f555f3f7f04d75
https://doi.org/10.1101/2022.06.02.494588
https://doi.org/10.1101/2022.06.02.494588
Autor:
Yogesh, Sutar, Sophie R, Fulton, Sagarkumar, Paul, Sophie, Altamirano, Susmit, Mhatre, Hiwa, Saeed, Pratikkumar, Patel, Sudipta, Mallick, Roopal, Bhat, Vandana B, Patravale, Harsh, Chauhan, Kirsten, Nielsen, Abhijit A, Date
Publikováno v:
ACS Infect Dis
As the existing therapeutic modalities for the treatment of cryptococcal meningitis (CM) have suboptimal efficacy, repurposing existing drugs for the treatment of CM is of great interest. The FDA-approved anthelmintic benzimidazoles, albendazole, meb
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-11 (2021)
Clinically approved anti-coagulant Fondaparinux is safe since it has zero contamination problems often associated with animal based heparins. Fondaparinux is a synthetic pentasaccharide based on the antithrombin-binding domain of Heparin sulfate and