Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yogesh D. Shejul"'
Autor:
Amol Magdum, Anil Panmand, Ravi K. Bhamidipati, Amol A. Raje, Vamsi Madgula, Ganesh Bhat, Meena Patel, Sreekanth R. Rouduri, Siddhartha De, Yogesh D. Shejul, Rajesh Bonagiri, Vandna Prasad, Anita Chugh, Ashwinkumar V. Meru, Vidya Ramdas, Sujay Basu, Dinesh A. Barawkar, Venkata P. Palle, Azfar Quraishi, Narayanan Hariharan, Sumit Chaudhary, Kasim A. Mookhtiar, Indraneel Ghosh, Minakshi Naykodi, K. Kashinath, Sachin Thorat
Publikováno v:
ACS Medicinal Chemistry Letters. 8:835-840
Adenosine A2A receptor (A2AAdoR) antagonism is a nondopaminergic approach to Parkinson's disease treatment that is under development. Earlier we had reported the therapeutic potential of 7-methoxy-4-morpholino-benzothiazole derivatives as A2AAdoR ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b859d65370dfe38949bf73f0a518820a
https://doi.org/10.1021/acsmedchemlett.7b00175
https://doi.org/10.1021/acsmedchemlett.7b00175
Autor:
Dinesh A. Barawkar, Siddhartha De, Yogesh Waman, Ashwinkumar V. Meru, Vidya Ramdas, Kasim A. Mookhtiar, Srinivasa B. Reddy, Sumit Chaudhary, Sujay Basu, Santosh Kumar Madadi, Rhishikesh Thakare, Venkata P. Palle, Anita Chugh, Gaurav Bedse, Summon Koul, Srinivas Rao Chennamaneni, Yogesh D. Shejul, Neela Prasad, Sandhya Chaturvedi, Rajesh Bonagiri, Suraj Menon, Jayasagar Gundu
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:1963-1975
Multipronged approach was used to synthesize a library of diverse C-8 cyclopentyl hypoxanthine analogs from a common intermediate III. Several potent and selective compounds were identified and evaluated for pharmacokinetic (PK) properties in Wistar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b73a7719123cbbcc1c1f7988f5140d8c
https://doi.org/10.1016/j.bmc.2017.02.029
https://doi.org/10.1016/j.bmc.2017.02.029
Autor:
Azfar Quraishi, Anita Chug, Suraj Menon, Vishal Unadkat, Sujay Basu, Madhav S. Seervi, Vandna Prasad, Sumit Chaudhary, Yogesh D. Shejul, Ganesh Bhat, Sachin Thorat, Ravi K. Bhamidipati, Shariq S. Ansari, Ashwinkumar V. Meru, Rhishikesh Thakare, Kasim A. Mookhtiar, Yogesh Salve, Venkata P. Palle, Minakshi Naykodi, Siddhartha De, Vaibhav Jain, Harish Patil, Indraneel Ghosh, Dinesh A. Barawkar, Meena Patel, Sreekanth R. Rouduri
Publikováno v:
Journal of Medicinal Chemistry. 60:681-694
Our initial structure–activity relationship studies on 7-methoxy-4-morpholino-benzothiazole derivatives featured by aryloxy-2-methylpropanamide moieties at the 2-position led to identification of compound 25 as a potent and selective A2A adenosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04044ccde58cf238c9369505eaf87036
https://doi.org/10.1021/acs.jmedchem.6b01584
https://doi.org/10.1021/acs.jmedchem.6b01584
Autor:
Sujay, Basu, Dinesh A, Barawkar, Vidya, Ramdas, Minakshi, Naykodi, Yogesh D, Shejul, Meena, Patel, Sachin, Thorat, Anil, Panmand, K, Kashinath, Rajesh, Bonagiri, Vandna, Prasad, Ganesh, Bhat, Azfar, Quraishi, Sumit, Chaudhary, Amol, Magdum, Ashwinkumar V, Meru, Indraneel, Ghosh, Ravi K, Bhamidipati, Amol A, Raje, Vamsi L M, Madgula, Siddhartha, De, Sreekanth R, Rouduri, Venkata P, Palle, Anita, Chugh, Narayanan, Hariharan, Kasim A, Mookhtiar
Publikováno v:
ACS medicinal chemistry letters. 8(8)
Adenosine A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54aaa72e45a440806a9999ba7b800c85
https://pubmed.ncbi.nlm.nih.gov/28835798
https://pubmed.ncbi.nlm.nih.gov/28835798
Autor:
Sujay, Basu, Dinesh A, Barawkar, Sachin, Thorat, Yogesh D, Shejul, Meena, Patel, Minakshi, Naykodi, Vaibhav, Jain, Yogesh, Salve, Vandna, Prasad, Sumit, Chaudhary, Indraneel, Ghosh, Ganesh, Bhat, Azfar, Quraishi, Harish, Patil, Shariq, Ansari, Suraj, Menon, Vishal, Unadkat, Rhishikesh, Thakare, Madhav S, Seervi, Ashwinkumar V, Meru, Siddhartha, De, Ravi K, Bhamidipati, Sreekanth R, Rouduri, Venkata P, Palle, Anita, Chug, Kasim A, Mookhtiar
Publikováno v:
Journal of medicinal chemistry. 60(2)
Our initial structure-activity relationship studies on 7-methoxy-4-morpholino-benzothiazole derivatives featured by aryloxy-2-methylpropanamide moieties at the 2-position led to identification of compound 25 as a potent and selective A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6669e08bb0eb3701d249b4c3c0ab153e
https://pubmed.ncbi.nlm.nih.gov/28055204
https://pubmed.ncbi.nlm.nih.gov/28055204
Autor:
Summon, Koul, Vidya, Ramdas, Dinesh A, Barawkar, Yogesh B, Waman, Neela, Prasad, Santosh Kumar, Madadi, Yogesh D, Shejul, Rajesh, Bonagiri, Sujay, Basu, Suraj, Menon, Srinivasa B, Reddy, Sandhya, Chaturvedi, Srinivas Rao, Chennamaneni, Gaurav, Bedse, Rhishikesh, Thakare, Jayasagar, Gundu, Sumit, Chaudhary, Siddhartha, De, Ashwinkumar V, Meru, Venkata, Palle, Anita, Chugh, Kasim A, Mookhtiar
Publikováno v:
Bioorganicmedicinal chemistry. 25(6)
Multipronged approach was used to synthesize a library of diverse C-8 cyclopentyl hypoxanthine analogs from a common intermediate III. Several potent and selective compounds were identified and evaluated for pharmacokinetic (PK) properties in Wistar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::74a6336b55423e20eedfab3de07966db
https://pubmed.ncbi.nlm.nih.gov/28238512
https://pubmed.ncbi.nlm.nih.gov/28238512
Autor:
Gagan Kukreja, Sophie Roy, Siddhartha De, Anita Chugh, Samuel D. Wright, Ravi P. Nargund, Suhas Tambe, Yogesh D. Shejul, Deepak B. Salunke, Michael P. Graziano, Jayasagar Gundu, Santosh Kurhade, Debnath Bhuniya, Kasim A. Mookhtiar, Sheo B. Singh, Joseph P. Vacca, Dhananjay N. Umrani, Bhavesh Dave, Minakshi Naykodi, Tian-Quan Cai, Sreemita Majumdar, Doris F. Cully, Prasun K. Chakravarty, Nadim S. Shaikh, Venkata P. Palle, Srinivasa B. Reddy, Prasad Shitole
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:3596-3602
GPR91, a 7TM G-Protein-Coupled Receptor, has been recently deorphanized with succinic acid as its endogenous ligand. Current literature indicates that GPR91 plays role in various pathophysiology including renal hypertension, autoimmune disease and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4824806ea8fdce58ee36cf56fffe0be4
https://doi.org/10.1016/j.bmcl.2011.04.091
https://doi.org/10.1016/j.bmcl.2011.04.091