Zobrazeno 1 - 10 of 240 pro vyhledávání: '"Yogesh C Awasthi"'
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Akademický článek
Role of SMC1 in overcoming drug resistance in triple negative breast cancer.
Autor: Sushma Yadav, Archana Sehrawat, Zeynep Eroglu, George Somlo, Robert Hickey, Sailee Yadav, Xueli Liu, Yogesh C Awasthi, Sanjay Awasthi
Publikováno v: PLoS ONE, Vol 8, Iss 5, p e64338 (2013)
Triple-negative breast cancer (TNBC) is one of the hardest subtypes of breast cancer to treat due to the heterogeneity of the disease and absence of well-defined molecular targets. Emerging evidence has shown the role of cohesin in the formation and
Externí odkaz: https://doaj.org/article/5d68bdeb965943b9b6c0cf4ed5c75dd8
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3
Data from Regression of Melanoma in a Murine Model by RLIP76 Depletion
Autor: Sanjay Awasthi, Yogesh C. Awasthi, Sharad S. Singhal
RLIP76/RALBP1 is a stress-responsive membrane protein implicated in the regulation of multiple cellular signaling pathways. It represents the predominant glutathione-conjugate transporter in cells, and our previous studies have shown that its inhibit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581a1bb2802419382569364170350980
https://doi.org/10.1158/0008-5472.c.6494973.v1
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Data from RLIP76 Is a Major Determinant of Radiation Sensitivity
Autor: Yogesh C. Awasthi, Berchmans John, Wendy E. Jarman, Paul Dent, Seema Dwivedi, Paul Boor, Adly Yacoub, Nancy Rowe, Dilki Wickramarachchi, Ewa Zajac, Aalok Nadkar, Kenneth Drake, Jyotsana Singhal, Sushma Yadav, Sharad S. Singhal, Sanjay Awasthi
RLIP76 (RALBP1) is a glutathione-conjugate transporter that is a critical component of clathrin-coated pit–mediated endocytosis, as well as in stress responses. In cultured cells, it provides protection from stressors including heat, oxidant chemic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b4f1735f185382be7476adc2bb3231
https://doi.org/10.1158/0008-5472.c.6493650
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Data from Regression of Lung and Colon Cancer Xenografts by Depleting or Inhibiting RLIP76 (Ral-Binding Protein 1)
Autor: Sanjay Awasthi, Yogesh C. Awasthi, Paul J. Boor, Seema Dwivedi, Sushma Yadav, Jyotsana Singhal, Sharad S. Singhal
Ral-binding protein 1 (RALBP1) is a stress-responsive and stress-protective multispecific transporter of glutathione conjugates (GS-E) and xenobiotic toxins. It is frequently overexpressed in malignant cells and plays a prominent antiapoptotic role s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebd05efd68c041ca9435841e3af98ef
https://doi.org/10.1158/0008-5472.c.6496563.v1
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10
Regulatory roles of glutathione-S-transferases and 4-hydroxynonenal in stress-mediated signaling and toxicity
Autor: Kota V. Ramana, Yogesh C. Awasthi, Pankaj Chaudhary, Sanjay Awasthi, Satish K. Srivastava
Publikováno v: Free Radical Biology and Medicine. 111:235-243
Glutathione-S-Transferases (GSTs) have primarily been thought to be xenobiotic metabolizing enzymes that protect cells from toxic drugs and environmental electrophiles. However, in last three decades, these enzymes have emerged as the regulators of o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19864c0ec6aec0a9b78a1334f4c3e4ce
https://doi.org/10.1016/j.freeradbiomed.2016.10.493
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