Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yogesh A. Karpe"'
Publikováno v:
Frontiers in Virology, Vol 4 (2024)
Chikungunya virus (CHIKV) is a vector-born alphavirus responsible for chikungunya fever with clinical manifestation of polyarthritis transmitted by Aedes aegypti and Aedes albopictus. Establishing viral pathogenesis needs host machinery modulation, a
Externí odkaz:
https://doaj.org/article/91a2bcf164dd4b3dbd195576deade335
Autor:
Yogesh A. Karpe
Publikováno v:
Frontiers in Virology, Vol 3 (2024)
Hepatitis E viruses (HEV) Open Reading Frame 1 (ORF1) encodes a non-structural polyprotein. In most positive-sense RNA viruses found in animals, this non-structural polyprotein is cleaved by viral protease or host protease. However, the mechanism beh
Externí odkaz:
https://doaj.org/article/435ac20628684a9eb18052fbc16d9f63
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Host-pathogen interactions are crucial for the successful propagation of pathogens inside the host cell. Knowledge of interactions between host proteins and viral proteins or viral RNA may provide clues for developing novel antiviral strategies. Hepa
Externí odkaz:
https://doaj.org/article/13e76a84267347348fba0c034228379e
Publikováno v:
Journal of Molecular Biology. 435:168050
Publikováno v:
Journal of Molecular Biology. 432:5322-5342
Viral pathogenesis is a complex event and its regulation involve dynamic interactions with various host factors, of which microRNAs are the key players. In the current study, we have identified the functional importance of an interplay between hepati
Publikováno v:
Journal of Molecular Biology. 432:2369-2387
Coordinated assembly of viral and host factors is essential for the successful propagation of viruses as well as the generation of host antiviral response. Previous studies from our group, as well as from other groups, have identified host proteins i
Publikováno v:
Journal of General Virology. 103
Publikováno v:
Journal of General Virology. 100:471-483
Hepatitis E virus (HEV) induces interferons and regulates the induction of interferon-stimulated genes (ISGs) in the host cell. HEV infection has been shown to promote the expression of different ISGs, such as ISG15, IFIT1, MX1, RSAD2/Viperin and CxC
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22336 (2011)
Chikungunya virus (CHIKV) is an insect borne virus (genus: Alphavirus) which causes acute febrile illness in humans followed by a prolonged arthralgic disease that affects the joints of the extremities. Re-emergence of the virus in the form of outbre
Externí odkaz:
https://doaj.org/article/c0acea855e9c4763a9016e5d94c83ca2
Publikováno v:
ACS Applied Materials & Interfaces. 9:35562-35573
Cancer treatment using siRNA based therapies pose various limitations such as off-target effects and degradation due to lack of specific delivery in desired cells. The aim of the present study was to develop multifunctional targeted nanoconstructs, w