Predicting mortality in febrile adults: comparative performance of the MEWS, qSOFA, and UVA scores using prospectively collected data among patients in four health-care sites in sub-Saharan Africa and South-Eastern AsiaResearch in context

Autor: Sham Lal, Manophab Luangraj, Suzanne H. Keddie, Elizabeth A. Ashley, Oliver Baerenbold, Quique Bassat, John Bradley, John A. Crump, Nicholas A. Feasey, Edward W. Green, Kevin C. Kain, Ioana D. Olaru, David G. Lalloo, Chrissy h. Roberts, David C.W. Mabey, Christopher C. Moore, Heidi Hopkins, Sara Ajanovic, Benjamin Amos, Stéphanie Baghoumina, Núria Balanza, Tsitsi Bandason, Tapan Bhattacharyya, Stuart D. Blacksell, Zumilda Boca, Christian Bottomley, Justina M. Bramugy, Clare IR. Chandler, Vilada Chansamouth, Mabvuto Chimenya, Joseph Chipanga, Anelsio Cossa, Ethel Dauya, Catherine Davis, Xavier de Lamballerie, Justin Dixon, Somyoth Douangphachanh, Audrey Dubot-Pérès, Michelle M. Durkin, Rashida A. Ferrand, Colin Fink, Elizabeth JA. Fitchett, Alessandro Gerada, Stephen R. Graves, Edward Green, Becca L. Handley, Coll D. Hutchison, Risara Jaksuwan, Jessica Jervis, Jayne Jones, Khamxeng Khounpaseuth, Katharina Kranzer, Khamfong Kunlaya, Pankaj Lal, Yoel Lubell, David CW. Mabey, Eleanor MacPherson, Forget Makoga, Sengchanh Manichan, Tegwen Marlais, Florian Maurer, Mayfong Mayxay, Michael Miles, Polycarp Mogeni, Campos Mucasse, Paul N. Newton, Chelsea Nguyen, Vilayouth Phimolsarnnousith, Mathieu Picardeau, Chrissy H. Roberts, Amphone Sengduangphachanh, Siho Sengsavang, Molly Sibanda, Somvai Singha, John Stenos, Ampai Tanganuchitcharnchai, Hira Tanvir, James E. Ussher, Marta Valente, Marie A. Voice, Manivanh Vongsouvath, Msopole Wamaka, L Joseph Wheat, Shunmay Yeung

Publikováno v: EClinicalMedicine, Vol 77, Iss , Pp 102856- (2024)

Summary: Background: Clinical severity scores can identify patients at risk of severe disease and death, and improve patient management. The modified early warning score (MEWS), the quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA),

Externí odkaz: https://doaj.org/article/472ab60c07af4c819f058bc83c88007e

Expanding the roles of community health workers to sustain programmes during malaria elimination: a meeting report on operational research in Southeast Asia

Autor: Lek Dysoley, James J. Callery, Voeurng Bunreth, Moul Vanna, Chan Davoeung, Yok Sovann, Sles You, Sam Ol, Rupam Tripura, Rusheng Chew, Arjun Chandna, Céline Christiansen-Jucht, Jayme Hughes, Nguon Sokomar, Top Sophornarann, Jeanne Rideout, Tat Veyvath, Oum Sarith, Thaung Puthy, Hay Sothearoth, Sen Sam An, Sazid Ibna Zaman, Lorenz von Seidlein, Lim Vanthy, Preap Sodavuth, Chrun Vannak, Arjen M. Dondorp, Yoel Lubell, Richard J. Maude, Thomas J. Peto, Bipin Adhikari

Publikováno v: Malaria Journal, Vol 23, Iss 1, Pp 1-10 (2024)

Abstract In Southeast Asia malaria elimination is targeted by 2030. Cambodia aims to achieve this by 2025, driven in large part by the urgent need to control the spread of artemisinin-resistant falciparum malaria infections. Rapid elimination depends

Externí odkaz: https://doaj.org/article/41ade5fce8b5462da2c38af623dfedd8

Cost-effectiveness analysis of a multiplex lateral flow rapid diagnostic test for acute non-malarial febrile illness in rural Cambodia and BangladeshResearch in context

Autor: Rusheng Chew, Chris Painter, Wirichada Pan-ngum, Nicholas Philip John Day, Yoel Lubell

Publikováno v: The Lancet Regional Health - Southeast Asia, Vol 23, Iss , Pp 100389- (2024)

Summary: Background: Multiplex lateral flow rapid diagnostic tests (LF-RDTs) may aid management of patients with acute non-malarial febrile illness (NMFI) in rural south and southeast Asia. We aimed to evaluate the cost-effectiveness in Cambodia and

Externí odkaz: https://doaj.org/article/b0b752e47e7c4ef5955a3857997495d4

External validation of clinical severity scores to guide referral of paediatric acute respiratory infections in resource-limited primary care settings

Autor: Arjun Chandna, Lazaro Mwandigha, Constantinos Koshiaris, Direk Limmathurotsakul, Francois Nosten, Yoel Lubell, Rafael Perera-Salazar, Claudia Turner, Paul Turner

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)

Abstract Accurate and reliable guidelines for referral of children from resource-limited primary care settings are lacking. We identified three practicable paediatric severity scores (the Liverpool quick Sequential Organ Failure Assessment (LqSOFA),

Externí odkaz: https://doaj.org/article/91533c136d0748c084da16e93ff2b4b3

Defining the role of host biomarkers in the diagnosis and prognosis of the severity of childhood pneumonia: a prospective cohort study

Autor: Arjun Chandna, Yoel Lubell, Lazaro Mwandigha, Phattaranit Tanunchai, Asama Vinitsorn, Melissa Richard-Greenblatt, Constantinos Koshiaris, Direk Limmathurotsakul, Francois Nosten, Mohammad Yazid Abdad, Rafael Perera-Salazar, Claudia Turner, Paul Turner

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)

Abstract Reliable tools to inform outpatient management of childhood pneumonia in resource-limited settings are needed. We investigated the value added by biomarkers of the host infection response to the performance of the Liverpool quick Sequential

Externí odkaz: https://doaj.org/article/e90069235fb84152825f5a03f28aff75