Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Yoav Gothilf"'
Autor:
Shir Confino, Yair Wexler, Adar Medvetzky, Yotam Elazary, Zohar Ben-Moshe, Joel Reiter, Talya Dor, Simon Edvardson, Gali Prag, Tamar Harel, Yoav Gothilf
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/174f901275894aea8a8f1df4fba873a5
Autor:
Nicole Roisman-Geller, Odelia Pisanty, Alon Weinberger, Deodatta S. Gajbhiye, Matan Golan, Yoav Gothilf
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7332 (2024)
LIM homeobox 4 (LHX4) is a transcription factor crucial for anterior pituitary (AP) development. Patients with LHX4 mutation suffer from combined pituitary hormone deficiency (CPHD), short statures, reproductive and metabolic disorders and lethality
Externí odkaz:
https://doaj.org/article/9dbe7f6674c94f8d9f8412a7807b5efc
Autor:
Ivan Bassi, Francesca Luzzani, Federica Marelli, Valeria Vezzoli, Ludovica Cotellessa, David A. Prober, Luca Persani, Yoav Gothilf, Marco Bonomi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Prokineticin receptors (PROKR1 and PROKR2) are G protein-coupled receptors which control human central and peripheral reproductive processes. Importantly, allelic variants of PROKR2 in humans are associated with altered migration of GnRH neu
Externí odkaz:
https://doaj.org/article/a5f5f89f259a47f8945dc2ba1d98ee2d
Autor:
Avital Baniel, Limor Ziv, Zohar Ben-Moshe, Ofer Sarig, Janan Mohamad, Alon Peled, Gideon Rechavi, Yoav Gothilf, Eli Sprecher
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3192 (2022)
Background: Gain-of-function mutations in CARD14 have recently been shown to be involved in the pathogenesis of psoriasis and pityriasis rubra pilaris (PRP). Those mutations were found to activate the NF-kB signaling pathway. Objective: Zebrafish is
Externí odkaz:
https://doaj.org/article/ed303753e0f64c718a3a5cbadf779228
Autor:
Gennaro Ruggiero, Zohar Ben-Moshe Livne, Yair Wexler, Nathalie Geyer, Daniela Vallone, Yoav Gothilf, Nicholas S. Foulkes
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
The zebrafish represents a powerful model for exploring how light regulates the circadian clock due to the direct light sensitivity of its peripheral clocks, a property that is retained even in organ cultures as well as zebrafish-derived cell lines.
Externí odkaz:
https://doaj.org/article/511f951e17a54495a50184b15a413aed
Autor:
Shir Confino, Talya Dor, Adi Tovin, Yair Wexler, Zohar Ben-Moshe Livne, Michaela Kolker, Odelia Pisanty, Sohyun Kathy Park, Nathalie Geyer, Joel Reiter, Shimon Edvardson, Hagar Mor-Shaked, Orly Elpeleg, Daniela Vallone, Lior Appelbaum, Nicholas S. Foulkes, Yoav Gothilf
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2373 (2022)
The circadian clock, which drives a wide range of bodily rhythms in synchrony with the day–night cycle, is based on a molecular oscillator that ticks with a period of approximately 24 h. Timed proteasomal degradation of clock components is central
Externí odkaz:
https://doaj.org/article/b1dc05bb03374457be9362a550e68a97
Autor:
Giulia Zuccarini, Ilaria D’Atri, Erika Cottone, Ken Mackie, Inbal Shainer, Yoav Gothilf, Paolo Provero, Patrizia Bovolin, Giorgio Roberto Merlo
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 168 (2019)
The G protein-coupled cannabinoid receptors type 1 (CB1R) and type 2 (CB2R), and their endocannabinoid (eCBs) ligands, have been implicated in several aspects of brain wiring during development. Here we aim to assess whether interfering with CB1R aff
Externí odkaz:
https://doaj.org/article/3df07e94675f45339ff133ad64ad2584
Autor:
Hadas E Sloin, Gennaro Ruggiero, Amir Rubinstein, Sima Smadja Storz, Nicholas S Foulkes, Yoav Gothilf
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199777 (2018)
BACKGROUND:TGF-β signaling is a cellular pathway that functions in most cells and has been shown to play a role in multiple processes, such as the immune response, cell differentiation and proliferation. Recent evidence suggests a possible interacti
Externí odkaz:
https://doaj.org/article/d6c3d3fa99804541ba27f47ab5721f0f
Autor:
Zohar Ben-Moshe Livne, Shahar Alon, Daniela Vallone, Yared Bayleyen, Adi Tovin, Inbal Shainer, Laura G Nisembaum, Idit Aviram, Sima Smadja-Storz, Michael Fuentes, Jack Falcón, Eli Eisenberg, David C Klein, Harold A Burgess, Nicholas S Foulkes, Yoav Gothilf
Publikováno v:
PLoS Genetics, Vol 12, Iss 11, p e1006445 (2016)
The master circadian clock in fish has been considered to reside in the pineal gland. This dogma is challenged, however, by the finding that most zebrafish tissues contain molecular clocks that are directly reset by light. To further examine the role
Externí odkaz:
https://doaj.org/article/ea03d4f90eda47e4a4f4962ec6512567
Publikováno v:
Marine Drugs, Vol 9, Iss 5, Pp 906-921 (2011)
Arylalkylamine N-acetyltransferase (AANAT) catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to arylalkylamines, including indolethylamines and phenylethylamines. Multiple aanats are present in teleost fish as a result of whole
Externí odkaz:
https://doaj.org/article/513e6b307e6243f3a987d0eafd1f421a