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of 10
pro vyhledávání: '"Yoav, Biala"'
Publikováno v:
The Journal of Physiology. 599:3735-3754
KEY POINTS Stimulation of postsynaptic muscarinic receptors was shown to excite principal hippocampal neurons by modulating several membrane ion conductances. We show here that activation of postsynaptic muscarinic receptors also causes neuronal exci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd099c6a7e42a9336387aaf5c1d13952
https://doi.org/10.1113/jp281460
https://doi.org/10.1113/jp281460
Publikováno v:
J Neurosci
Brain insults, such as trauma, stroke, anoxia, and status epilepticus (SE), cause multiple changes in synaptic function and intrinsic properties of surviving neurons that may lead to the development of epilepsy. Experimentally, a single SE episode, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0012fd25b6e4926edb31300835a31855
https://doi.org/10.1523/jneurosci.1603-19.2019
https://doi.org/10.1523/jneurosci.1603-19.2019
Publikováno v:
The Journal of physiologyReferences. 599(15)
Stimulation of postsynaptic muscarinic receptors was shown to excite principal hippocampal neurons by modulating several membrane ion conductances. We show here that activation of postsynaptic muscarinic receptors also causes neuronal excitation by i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::398ec5e8513be946752c2fbf5509d72f
https://pubmed.ncbi.nlm.nih.gov/34148230
https://pubmed.ncbi.nlm.nih.gov/34148230
Publikováno v:
Hippocampus
In many types of CNS neurons, repetitive spiking produces a slow afterhyperpolarization (sAHP), providing sustained, intrinsically generated negative feedback to neuronal excitation. Changes in the sAHP have been implicated in learning behaviors, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ba2598d413f60637abb43c949e2085
https://doi.org/10.1002/hipo.22836
https://doi.org/10.1002/hipo.22836
The Na(+)/K(+)-ATPase (NKA) is a ubiquitous membrane-bound enzyme responsible for generating and maintaining the Na(+) and K(+) electrochemical gradients across the plasmalemma of living cells. Numerous studies in non-neuronal tissues have shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816540bfaecb222e2d19b97e26b294ac
https://europepmc.org/articles/PMC6616281/
https://europepmc.org/articles/PMC6616281/
Publikováno v:
Biochemistry. 48:12329-12336
RIC-3 belongs to a conserved family of proteins influencing maturation of nicotinic acetylcholine receptors (nAChRs). RIC-3 homologues were shown to differently affect different nAChRs. Here we show that coexpression with RIC-3 increases the level of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f455a3cedfb3195f8e366a03028ce625
https://doi.org/10.1021/bi901234a
https://doi.org/10.1021/bi901234a
Publikováno v:
Molecular Biology of the Cell. 20:1419-1427
RIC-3 belongs to a conserved family of proteins influencing nicotinic acetylcholine receptor (nAChR) maturation. RIC-3 proteins are integral membrane proteins residing in the endoplasmic reticulum (ER), and containing a C-terminal coiled-coil domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f5cee2cae506f85cd1ac9f4d664010
https://doi.org/10.1091/mbc.e08-08-0851
https://doi.org/10.1091/mbc.e08-08-0851
Autor:
Ophir Lavon, Lyn Kamintsky, Shai Shrot, Igor Makarovsky, Yoel Yaari, Moshe Daninos, Amir Krivoy, Guy Bar-Klein, Liran Statlender, Alon Friedman, Erez Ramaty, Michael Kassirer, Yoav Biala, Yossi Rosman
Publikováno v:
Toxicology. 323
Poisoning with organophosphates (OPs) may induce status epilepticus (SE), leading to severe brain damage. Our objectives were to investigate whether OP-induced SE leads to the emergence of spontaneous recurrent seizures (SRSs), the hallmark of chroni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640ee590fd3406dde506aad6b09ab8e5
https://pubmed.ncbi.nlm.nih.gov/24881594
https://pubmed.ncbi.nlm.nih.gov/24881594
Autor:
Eugenia, Yakunin, Virginie, Loeb, Haya, Kisos, Yoav, Biala, Shlomo, Yehuda, Yoel, Yaari, Dennis J, Selkoe, Ronit, Sharon
Publikováno v:
Brain pathology (Zurich, Switzerland). 22(3)
α-synuclein (α-Syn) is a neuronal protein that accumulates progressively in Parkinson’s disease and related synucleinopathies. Attempting to identify cellular factors that affect α-Syn neuropathology, we previously reported that polyunsaturated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52be6145a1c28e93b1234c58bc544469
https://pubmed.ncbi.nlm.nih.gov/21929559
https://pubmed.ncbi.nlm.nih.gov/21929559
Publikováno v:
Journal of cell science. 122(Pt 6)
RIC-3 is a member of a conserved family of proteins that affect nicotinic acetylcholine receptor maturation. In yeast and in vitro, BATH-42, a BTB- and MATH-domain-containing protein, interacts with RIC-3. BATH-42 is also known to interact with the C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428e207be1e60aef79bb863841472012
https://pubmed.ncbi.nlm.nih.gov/19223395
https://pubmed.ncbi.nlm.nih.gov/19223395