Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yoanne D Mouwenda"'
Autor:
Madeleine Eunice Betouke Ongwe, Yoanne D Mouwenda, Koen A Stam, Peter G Kremsner, Bertrand Lell, David Diemert, Jeff Bethony, Maria E Bottazzi, Peter J Hotez, Remko V Leeuwen, Martin P Grobusch, Ayola A Adegnika, Oleg A Mayboroda, Maria Yazdanbakhsh
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0275013 (2022)
Metabolomics provides a powerful tool to study physiological changes in response to various perturbations such as vaccination. We explored whether metabolomic changes could be seen after vaccination in a phase I trial where Gabonese adults living eit
Externí odkaz:
https://doaj.org/article/ed445e508fab47d0a4352a9fcd870d4f
Autor:
Yoanne D Mouwenda, Madeleine E Betouke Ongwe, Friederike Sonnet, Koen A Stam, Lucja A Labuda, Sophie De Vries, Martin P Grobusch, Frejus J Zinsou, Yabo J Honkpehedji, Jean-Claude Dejon Agobe, David J Diemert, Remko van Leeuwen, Maria E Bottazzi, Peter J Hotez, Peter G Kremsner, Jeffrey M Bethony, Simon P Jochems, Ayola A Adegnika, Marguerite Massinga Loembe, Maria Yazdanbakhsh
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009732 (2021)
Two hookworm vaccine candidates, Na-GST-1 and Na-APR-1, formulated with Glucopyranosyl Lipid A (GLA-AF) adjuvant, have been shown to be safe, well tolerated, and to induce antibody responses in a Phase 1 clinical trial (Clinicaltrials.gov NCT02126462
Externí odkaz:
https://doaj.org/article/74b241e8340f43ffaff17b49d024c36c
Autor:
Mikhael D. Manurung, Sanne E. de Jong, Yvonne Kruize, Yoanne D. Mouwenda, Madeleine Eunice Betouke Ongwe, Yabo Josiane Honkpehedji, Jeannot Frézus Zinsou, Jean Claude Dejon-Agobe, Stephen L. Hoffman, Peter G. Kremsner, Ayola Akim Adegnika, Rolf Fendel, Benjamin Mordmüller, Meta Roestenberg, Bertrand Lell, Maria Yazdanbakhsh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Controlled human malaria infection (CHMI) using cryopreserved non-attenuated Plasmodium falciparum sporozoites (PfSPZ) offers a unique opportunity to investigate naturally acquired immunity (NAI). By analyzing blood samples from 5 malaria-na
Externí odkaz:
https://doaj.org/article/c27d927e1b5843dab870f4f32ed86aa9
Autor:
Madeleine Eunice Betouke Ongwe, Isabelle Kohler, Mikhael D. Manurung, Aswin Verhoeven, Rico Derks, Jacqueline J. Janse, Yoanne D. Mouwenda, Peter G. Kremsner, Ayola A. Adegnika, Bertrand Lell, Bart Everts, Oleg A. Mayboroda, Maria Yazdanbakhsh
Publikováno v:
Metabolites, Vol 12, Iss 12, p 1224 (2022)
The interaction of malaria parasites with their human host is extensively studied, yet only few studies reported how P. falciparum infection affects urinary metabolite profiles and how this is associated with immunity. We present a longitudinal study
Externí odkaz:
https://doaj.org/article/e55265ab675f4ebca1bc2efa4110b7b6
Autor:
Frejus Jeannot Zinsou, David Diemert, Jeffrey M. Bethony, Simon P. Jochems, Martin P. Grobusch, Yabo Josiane Honkpehedji, Sophie De Vries, Maria Elena Bottazzi, Peter J. Hotez, Remko van Leeuwen, Peter G. Kremsner, Friederike Sonnet, Jean-Claude Dejon Agobe, Ayola A. Adegnika, Yoanne D. Mouwenda, Koen A. Stam, Lucja A. Labuda, Marguerite Massinga Loembe, Madeleine E. Betouke Ongwe, Maria Yazdanbakhsh
Publikováno v:
PLOS NEGLECTED TROPICAL DISEASES, 15(10). PUBLIC LIBRARY SCIENCE
PLoS neglected tropical diseases, 15(10):e0009732. Public Library of Science
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009732 (2021)
PLoS neglected tropical diseases, 15(10):e0009732. Public Library of Science
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009732 (2021)
Two hookworm vaccine candidates, Na-GST-1 and Na-APR-1, formulated with Glucopyranosyl Lipid A (GLA-AF) adjuvant, have been shown to be safe, well tolerated, and to induce antibody responses in a Phase 1 clinical trial (Clinicaltrials.gov NCT02126462
Autor:
Martin P. Grobusch, Frejus Jeannot Zinsou, Peter G. Kremsner, Remko van Leeuwen, David Diemert, Sophia G. de Vries, Eunice M Betouke Ongwe, Benjamin Mordmueller, Marjan Molemans, Odilon Nouatin, Susana Pinto de Jesus, Jean-Claude Dejon Agobe, Ayola A. Adegnika, Emmanuel B. Bache, Selidji T Agnandji, Yabo J Honkepehedji, Kafui G Vodonou, Rodrigue Bikangui, Prince G Manouana, Peter J. Hotez, Bertrand Lell, Aurore Bouyoukou Hounkpatin, Maria Yazdanbakhsh, Marguerite Massinga Loembe, Anne-Marie Nkoma Mouima, Jean Ronald Edoa, Carsten Koehler, Guangzhao Li, Yoanne D. Mouwenda, Vera Kühne, Maria Elena Bottazzi, Jeffrey M. Bethony
Publikováno v:
The Lancet Infectious Diseases
The Lancet Infectious Diseases, 21(2), 275-285. ELSEVIER SCI LTD
The Lancet Infectious Diseases, 21(2), 275-285. ELSEVIER SCI LTD
Background Hookworms cause substantial morbidity in children and women of reproductive age. The control strategy of mass drug administration is suboptimal, hence the need for a vaccine. Necator americanus aspartic protease-1 (Na-APR-1) and N american
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb55fd2ffad7c271f775a2b2d818cb0
https://hdl.handle.net/1887/3214678
https://hdl.handle.net/1887/3214678
Autor:
Simon P. Jochems, Shohreh Azimi, Jelle J. Goeman, Marcel J. T. Reinders, Peter G. Kremsner, Sanne E. de Jong, Koen A. Stam, Meta Roestenberg, Frits Koning, B. Kim Lee Sim, Vincent van Unen, Mikhael D Manurung, Anna Vilanova, Benjamin Mordmüller, Elmar Eisemann, Rolf Fendel, Boudewijn P. F. Lelieveldt, Nicola Pezzotti, Maria Yazdanbakhsh, Yoanne D. Mouwenda, Yvonne C. M. Kruize, Stephen L. Hoffman, Madeleine Eunice Betouke Ongwe, Freia-Raphaella Lorenz, Marion H. König, Thomas Höllt, Bertrand Lell
Publikováno v:
Nature Immunology, 22, 5, pp. 654-665
Nature Immunology
Nature Immunology, 22(5)
Nature Immunology, 22, 654-665
Nature Immunology, 22(5), 654-665. NATURE RESEARCH
Nature Immunology
Nature Immunology, 22(5)
Nature Immunology, 22, 654-665
Nature Immunology, 22(5), 654-665. NATURE RESEARCH
Controlled human infections provide opportunities to study the interaction between the immune system and malaria parasites, which is essential for vaccine development. Here, we compared immune signatures of malaria-naive Europeans and of Africans wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab80d0879d5062e642566300a7b0d1e
https://repository.ubn.ru.nl/handle/2066/238471
https://repository.ubn.ru.nl/handle/2066/238471
Autor:
Marguerite Massinga-Loembe, José Francisco Fernandes, Ulysse Ateba-Ngoa, Jean Claude Dejon-Agobé, Peter G. Kremsner, Julie Engelhorn, Michael Theisen, Ayola A. Adegnika, Eunice M Betouke Ongwe, Albert Lalremruata, Yoanne D. Mouwenda, Odilon Nouatin, Bertrand Lell, Stephen L. Hoffman, Jean Ronald Edoa, Benjamin Mordmüller, Meral Esen, Andreas Homoet, B. Kim Lee Sim
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 69(8)
BackgroundGMZ2 is a recombinant malaria vaccine inducing immune responses against Plasmodium falciparum (Pf) merozoite surface protein-3 and glutamate-rich protein. We used standardized controlled human malaria infection (CHMI) to assess the efficacy