Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Yoanna Bello Arredondo"'
Autor:
Karen Krchma, Kapil Kapoor, Jian Su Shao, Dwight A. Towler, Bart O. Williams, Abraham Behrmann, Ranjan J. Perera, Carolyn Smith, Attila Kovacs, Su Li Cheng, Megan Mead, Yoanna Bello Arredondo, Bindu Ramachandran, Laurence M. Brill
Publikováno v:
Circulation Research. 117:142-156
Rationale: Wnt signaling regulates key aspects of diabetic vascular disease. Objective: We generated SM22-Cre;LRP6(fl/fl);LDLR −/− mice to determine contributions of Wnt coreceptor low-density lipoprotein receptor–related protein 6 (LRP6) in th
Autor:
Megan Mead, Bindu Ramachandran, Karen Krchma, Jian Su Shao, Yoanna Bello Arredondo, Robert E. Maxson, Dwight A. Towler, Su Li Cheng, Attila Kovacs, Abraham Behrmann
Publikováno v:
Diabetes. 63:4326-4337
When fed high-fat diets, male LDLR−/− mice develop obesity, hyperlipidemia, hyperglycemia, and arteriosclerotic calcification. An osteogenic Msx-Wnt regulatory program is concomitantly upregulated in the vasculature. To better understand the mech