CSAP Acts as a Regulator of TTLL-Mediated Microtubule Glutamylation

Autor: Guillaume Bompard, Juliette van Dijk, Julien Cau, Yoann Lannay, Guillaume Marcellin, Aleksandra Lawera, Siem van der Laan, Krzysztof Rogowski

Publikováno v: Cell Reports, Vol 25, Iss 10, Pp 2866-2877.e5 (2018)

Summary: Tubulin glutamylation is a reversible posttranslational modification that accumulates on stable microtubules (MTs). While abnormally high levels of this modification lead to a number of disorders such as male sterility, retinal degeneration,

Externí odkaz: https://doaj.org/article/60f5568afcb149a18d27eb9561072d9a

Evolutionary Divergence of Enzymatic Mechanisms for Tubulin Detyrosination

Autor: Andrew Burgess, Patrick Bastien, Guillaume Bompard, Krzysztof Rogowski, Yoann Lannay, Maude F. Lévêque, Lubomir Vezenkov, Sara Ovejero, Geronimo Dubra, Muriel Amblard, Guillaume Marcellin, Yvon Sterkers, Siem van der Laan, Serge Urbach

Publikováno v: Cell Reports, Vol 29, Iss 12, Pp 4159-4171.e6 (2019)
Cell Reports
Cell Reports, 2019, 29 (12), pp.4159-4171. ⟨10.1016/j.celrep.2019.11.074⟩
Cell Reports, Elsevier Inc, In press, ⟨10.1016/j.celrep.2019.11.074⟩
Cell Reports, Elsevier Inc, 2019, 29 (12), pp.4159-4171. ⟨10.1016/j.celrep.2019.11.074⟩

Summary: The two related members of the vasohibin family, VASH1 and VASH2, encode human tubulin detyrosinases. Here we demonstrate that, in contrast to VASH1, which requires binding of small vasohibin binding protein (SVBP), VASH2 has autonomous tubu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa6a79491a944ef1773c2c5f40dc9b1
http://www.sciencedirect.com/science/article/pii/S2211124719315657

Predicting suicidal behavior by an accurate monitoring of RNA editing biomarkers in blood samples

Autor: Yoann Lannay, S. Pointet, Guillaume Marcellin, D. Weissmann, B. Vire, Nicolas Salvetat, S. Van der Laan, F. Molina

Publikováno v: European Psychiatry. 41:s893-s894

IntroductionPredicting suicidal behaviors is one of the most complex challenges of daily psychiatric practices. Alterations of RNA editing of neurotransmitter receptors and other proteins have been shown to be involved in etiology of different psychi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::58009cf8ec75801fe635fffe50407efe
https://doi.org/10.1016/j.eurpsy.2017.01.1819

Expression Map of the Human Exome in CD34+ Cells and Blood Cells: Increased Alternative Splicing in Cell Motility and Immune Response Genes

Autor: S Tondeur, Said Assou, Céline Pangault, Thierry Fest, Jean-François Schved, Tanguy Le Carrour, Samir Hamamah, Bernard Klein, Yoann Lannay, Aurélie Cubizolle, John De Vos, Rima Benmahdi, Véronique Pantesco

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (2), pp.e8990. ⟨10.1371/journal.pone.0008990⟩
PLoS ONE, 2010, 5 (2), pp.e8990. ⟨10.1371/journal.pone.0008990⟩
PLoS ONE, Vol 5, Iss 2, p e8990 (2010)

International audience; BACKGROUND: Hematopoietic cells are endowed with very specific biological functions, including cell motility and immune response. These specific functions are dramatically altered during hematopoietic cell differentiation, whe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec5f78bbfbee6fe93cc6c6ccfd3e754
https://www.hal.inserm.fr/inserm-00453226