cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission.

Autor: Ghania Ramdani, Bernina Naissant, Eloise Thompson, Florence Breil, Audrey Lorthiois, Florian Dupuy, Ross Cummings, Yoann Duffier, Yolanda Corbett, Odile Mercereau-Puijalon, Kenneth Vernick, Donatella Taramelli, David A Baker, Gordon Langsley, Catherine Lavazec

Publikováno v: PLoS Pathogens, Vol 11, Iss 5, p e1004815 (2015)

Blocking Plasmodium falciparum transmission to mosquitoes has been designated a strategic objective in the global agenda of malaria elimination. Transmission is ensured by gametocyte-infected erythrocytes (GIE) that sequester in the bone marrow and a

Externí odkaz: https://doaj.org/article/03e94455a91049aea358d495affa9184

A humanized mouse model for sequestration of Plasmodium falciparum sexual stages and in vivo evaluation of gametocytidal drugs OPEN

Autor: Florian Dupuy, Yoann Duffier, Catherine Lavazec, Dominique Mazier, Audrey Lorthiois, Grégory Jouvion, Laurence Fiette, Pau Cisteró, Alfredo Mayor, Alicia Moreno Sabater

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6, pp.35025. <10.1038/srep35025>
Scientific Reports, Nature Publishing Group, 2016, 6, pp.35025. ⟨10.1038/srep35025⟩
Dipòsit Digital de la UB
Universidad de Barcelona
Scientific Reports, 2016, 6, pp.35025. ⟨10.1038/srep35025⟩
Scientific Reports, Nature Publishing Group, 2016, 6, pp.35025. 〈10.1038/srep35025〉
Recercat. Dipósit de la Recerca de Catalunya
instname

International audience; The development of new drugs to disrupt malaria transmission requires the establishment of an in vivo model to address the biology of Plasmodium falciparum sexual stages (gametocytes). Herein we show that chemically immune-mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b00761249d1cc89f08b85d0250de5e8
http://www.hal.inserm.fr/inserm-01472181