Indices of sarcopenic obesity are important predictors of finite element analysis-derived bone strength in older adults with obesity

Autor: Giulia Gregori, Arjun Paudyal, Yoann Barnouin, Alessandra Celli, Martha Belen Segoviano-Escobar, Reina Armamento-Villareal, Nicola Napoli, Clifford Qualls, Dennis T. Villareal

Publikováno v: Frontiers in Endocrinology, Vol 14 (2023)

BackgroundThe expanding population of older adults with obesity is a public health challenge, in part, because of the increased risk of fractures despite normal or high bone mineral density. Potential factors predisposing to fractures in this group i

Externí odkaz: https://doaj.org/article/c58c580979674352a25bff8d5be0f9d2

Cognitive response to testosterone replacement added to intensive lifestyle intervention in older men with obesity and hypogonadism: prespecified secondary analyses of a randomized clinical trial

Autor: Yoann Barnouin, Giulia Gregori, Dennis T. Villareal, Nicola Napoli, Arjun Paudyal, Clifford Qualls, Alessandra Celli, Reina Armamento-Villareal

Publikováno v: Am J Clin Nutr

BACKGROUND: Both obesity and hypogonadism are common in older men which could additively exacerbate age-related declines in cognitive function. However, little is known about the effects of lifestyle intervention plus testosterone replacement therapy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575a13dc6f1f0f4f416f95a7a1bc3629
https://europepmc.org/articles/PMC8588849/

OR02-05 Effect of Testosterone Replacement Therapy Added to Intensive Lifestyle Intervention on Cognitive Functions in Frail, Older Veterans with Hypogonadism and Obesity: A Randomized Clinical Trial

Autor: Giulia Gregori, Alessandra Celli, Reina Condevillamar Villareal, Arjun Paudyal, Yoann Barnouin, Dennis T. Villareal, Clifford Quallas

Publikováno v: Journal of the Endocrine Society

Background: Both hypogonadism and obesity are common in older men which might additively exacerbate their age-related decline in cognitive functions. We tested the hypothesis that the addition of testosterone replacement therapy to intensive lifestyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f71b28c8817eae4de5bad8aac3a5fba
http://europepmc.org/articles/PMC7209593

Dysregulation of C-X-C motif ligand 10 during aging and association with cognitive performance

Autor: Jean-Yves Hogrel, Gillian Butler-Browne, Liam Bagley, Steven Bradburn, Nasser Al-Shanti, Chris Murgatroyd, David M. A. Mann, Neil Pendleton, Marco Narici, Mati Pääsuke, Andrew C Robinson, Yoann Barnouin, Michael C. Carroll, Antony Payton, Helena Gapeyeva, Sarianna Sipilä, Mark Slevin, Jamie S. McPhee, Andrea B. Maier

Publikováno v: Neurobiology of Aging
Neurobiology of Aging, 2017, 63, pp.54-64. ⟨10.1016/j.neurobiolaging.2017.11.009⟩
Bradburn, S, McPhee, J, Bagley, L, Carroll, M, Slevin, M, Al-Shanti, N, Barnouin, Y, Hogrel, J-Y, Pääsuke, M, Gapeyeva, H, Maier, A, Sipilä, S, Narici, M, Robinson, A, Mann, D, Payton, A, Pendleton, N, Butler-Browne, G & Murgatroyd, C 2018, ' Dysregulation of C-X-C motif ligand 10 during aging and association with cognitive performance ', Neurobiology of Aging, vol. 63, pp. 54-64 . https://doi.org/10.1016/j.neurobiolaging.2017.11.009
Neurobiology of Aging, Elsevier, 2017, 63, pp.54-64. ⟨10.1016/j.neurobiolaging.2017.11.009⟩
Neurobiology of Aging, 63, 54-64. Elsevier Inc.

International audience; Chronic low-grade inflammation during aging (inflammaging) is associated with cognitive decline and neurodegeneration; however, the mechanisms underlying inflammaging are unclear. We studied a population (n = 361) of healthy y

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5b6f921af550b5b225fafb0ce1cc8a
https://doi.org/10.1016/j.neurobiolaging.2017.11.009

Association of interleukin-6 rs1800796 polymorphism with reduced cognitive performance in healthy older adults

Autor: Marco Narici, Yoann Barnouin, Mati Pääsuke, Natalia Ewa Bezuch, Jean-Yves Hogrel, Chris Murgatroyd, Gillian Butler-Browne, Steven Bradburn, Helena Gapeyeva, Jamie S. McPhee, Andrea B. Maier, Sarianna Sipilä

Publikováno v: Bezuch, N E, Bradburn, S, Sipilä, S, Pääsuke, M, Gapeyeva, H, Maier, A B, Hogrel, J Y, Barnouin, Y, Butler-Browne, G, Narici, M, McPhee, J & Murgatroyd, C 2019, ' Association of interleukin-6 rs1800796 polymorphism with reduced cognitive performance in healthy older adults ', Meta Gene, vol. 19, pp. 51-55 . https://doi.org/10.1016/j.mgene.2018.10.007
Meta Gene, 19, 51-55. Elsevier BV

© 2018 Elsevier B.V. With increasing life expectancy, age-associated cognitive impairment is an escalating problem worldwide. Inflammation is one of the features that characterises cognitive decline and can stimulate neurodegeneration. Interleukin 6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d930fa50823e22ae9449503a5c4e32d
https://hdl.handle.net/1871.1/fa3f3466-29ad-4070-9af4-2d439be616cf