Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yoalli Martínez-Pérez"'
Autor:
Luis A. Flores-López, Ignacio De la Mora-De la Mora, Claudia M. Malagón-Reyes, Itzhel García-Torres, Yoalli Martínez-Pérez, Gabriela López-Herrera, Gloria Hernández-Alcántara, Gloria León-Avila, Gabriel López-Velázquez, Alberto Olaya-Vargas, Saúl Gómez-Manzo, Sergio Enríquez-Flores
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1295 (2024)
T-cell acute lymphoblastic leukemia (T-ALL) is a challenging childhood cancer to treat, with limited therapeutic options and high relapse rates. This study explores deamidated triosephosphate isomerase (dTPI) as a novel therapeutic target. We hypothe
Externí odkaz:
https://doaj.org/article/b5729f43f091488fb264b0a8adec80dc
Autor:
Sergio Enríquez-Flores, Luis A. Flores-López, Ignacio De la Mora-De la Mora, Itzhel García-Torres, Isabel Gracia-Mora, Pedro Gutiérrez-Castrellón, Cynthia Fernández-Lainez, Yoalli Martínez-Pérez, Alberto Olaya-Vargas, Paul de Vos, Gabriel López-Velázquez
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Human triosephosphate isomerase (HsTIM) is a central glycolytic enzyme and is overexpressed in cancer cells with accelerated glycolysis. Triple-negative breast cancer is highly dependent on glycolysis and is typically treated with a combinat
Externí odkaz:
https://doaj.org/article/8e40f3105af14974bb2c5361fb6ece02
Autor:
Sergio Enríquez-Flores, Ignacio De la Mora-De la Mora, Itzhel García-Torres, Luis A. Flores-López, Yoalli Martínez-Pérez, Gabriel López-Velázquez
Publikováno v:
Molecules, Vol 28, Iss 16, p 6163 (2023)
Cancer involves a series of diseases where cellular growth is not controlled. Cancer is a leading cause of death worldwide, and the burden of cancer incidence and mortality is rapidly growing, mainly in developing countries. Many drugs are currently
Externí odkaz:
https://doaj.org/article/594ffe6f4c8d4dd4914b5b7e377db877
Autor:
Sergio Enríquez-Flores, Luis Antonio Flores-López, Itzhel García-Torres, Ignacio de la Mora-de la Mora, Nallely Cabrera, Pedro Gutiérrez-Castrellón, Yoalli Martínez-Pérez, Gabriel López-Velázquez
Publikováno v:
Biomolecules, Vol 10, Iss 7, p 1050 (2020)
Therapeutic strategies for the treatment of any severe disease are based on the discovery and validation of druggable targets. The human genome encodes only 600–1500 targets for small-molecule drugs, but posttranslational modifications lead to a co
Externí odkaz:
https://doaj.org/article/407d27b9f7e548b382985fd67ec72129
Autor:
Luis A. Flores López, Sergio Enríquez-Flores, Paul de Vos, Itzhel García-Torres, Isabel Gracia-Mora, Alberto Olaya-Vargas, Gabriel López-Velázquez, Yoalli Martínez-Pérez, Ignacio de la Mora-de la Mora, Cynthia Fernández-Lainez, Pedro Gutiérrez-Castrellón
Human TPI (HsTPI) is a central and essential glycolytic enzyme for energy supply and is overexpressed in cancer cells. Here, we investigated HsTPI as a potential target for inducing cell death in triple-hormone receptor-negative breast cancer, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d754d550bb238b3bb4e590f88ed1d84e
https://doi.org/10.1101/2021.11.09.467888
https://doi.org/10.1101/2021.11.09.467888
Autor:
Emma Saavedra, Mario Nequiz-Avendaño, Alfonso Olivos-García, Sergio Enríquez-Flores, Ruy Pérez-Tamayo, Edith Mendoza, Itzhel García-Torres, Gloria León-Ávila, Gabriel López-Velázquez, Marco Gudiño-Zayas, Yoalli Martínez-Pérez
Publikováno v:
Parasitology research. 119(10)
Amoebiasis is a human parasitic disease caused by Entamoeba histolytica. The parasite can invade the large intestine and other organs such as liver; resistance to the host tissue oxygen is a condition for parasite invasion and survival. Thioredoxin r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2fb82e3afa062362e21a700c82fc3b
https://pubmed.ncbi.nlm.nih.gov/32886229
https://pubmed.ncbi.nlm.nih.gov/32886229
Autor:
Ignacio de la Mora-de la Mora, Luis Antonio Flores-López, Sergio Enríquez-Flores, Nallely Cabrera, Yoalli Martínez-Pérez, Pedro Gutiérrez-Castrellón, Gabriel López-Velázquez, Itzhel García-Torres
Publikováno v:
Biomolecules, Vol 10, Iss 1050, p 1050 (2020)
Biomolecules
Volume 10
Issue 7
Biomolecules
Volume 10
Issue 7
Therapeutic strategies for the treatment of any severe disease are based on the discovery and validation of druggable targets. The human genome encodes only 600&ndash
1500 targets for small-molecule drugs, but posttranslational modifications lea
1500 targets for small-molecule drugs, but posttranslational modifications lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18574d2b53c130a17e7ed3b0576f5ebd
https://doi.org/10.3390/biom10071050
https://doi.org/10.3390/biom10071050
Autor:
Elizabeth Arlen Pineda-Peña, Pablo Muriel, Marina Galicia-Moreno, José Segovia, Liliana Favari, Araceli Navarrete, Aracely Evangelina Chávez-Piña, Yoalli Martínez-Pérez, Gilberto Castañeda-Hernández
Publikováno v:
European journal of pharmacology. 818
Adverse gastrointestinal (GI) effects caused by nonsteroidal anti-inflammatory drugs (NSAIDs), including indomethacin, are recognized as the major limitation to their clinical use. NSAID-induced gastric damage is generated by cyclooxygenase inhibitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbab283283393c3a6f3e2d4dff097bed
https://pubmed.ncbi.nlm.nih.gov/29154839
https://pubmed.ncbi.nlm.nih.gov/29154839