Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yo-Taro Shirai"'
Publikováno v:
Cancer Research. 83:1219-1219
Some types of thyroid cancers are known to arise from thyroid adenomas, as a malignant transition from benign adenoma, as proposed in the multi-step carcinogenesis model. Thyroid cancer studies using human thyroid cancer cell lines have been intensel
Autor:
Yo-Taro Shirai, Shigetoshi Yokoyama, Jorge Paiz, Masaaki Miyakoshi, Shioko Kimura, Jerrold M. Ward, Yoshinori Takizawa, Manabu Iwadate
Publikováno v:
Cancer Research. 81:2661-2661
The multi-step carcinogenesis model, including the adenoma-carcinoma sequence, has been proposed in many cancers including those of colon, pancreas, and thyroid. BRAF activation is among the reported gene mutations important for thyroid carcinogenesi
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
While thyroid is considered to be a dormant organ, when required, it can regenerate through increased cell proliferation. However, the mechanism for regeneration remains unknown. Nkx2-1(fl/fl);TPO-cre mouse thyroids exhibit a very disorganized appear
Autor:
Akira Watanabe, Hiroyuki Miyoshi, Akiyoshi Komuro, Yo Taro Shirai, Mitsunobu R. Kano, Masakazu Yashiro, Hiroyuki Aburatani, Kunihiko Kiyono, Kosei Hirakawa, Hiroshi Suzuki, Yasuyuki Morishita, Erik Johansson, Caname Iwata, Kohei Miyazono, Yoshiko Matsumoto
Publikováno v:
JNCI Journal of the National Cancer Institute
Background Diffuse-type gastric carcinoma is a cancer with poor prognosis that has high levels of transforming growth factor β (TGF-β) expression and thick stromal fibrosis. However, the association of TGF-β signaling with diffuse-type gastric car
Autor:
Yasuyuki Morishita, Masako Oka, Yukari Komuta, Caname Iwata, Kohei Miyazono, Mitsunobu R. Kano, Kazunori Kataoka, Yo Taro Shirai, Yasuyoshi Ouchi
Publikováno v:
Cancer Science. 100:173-180
There are a number of kinase inhibitors that regulate components of the neovasculature. We previously reported the use of transforming growth factor (TGF)-β inhibitor on neovasculature in stroma-rich tumor models to increase the intratumoral distrib
Autor:
Kosei Hirakawa, Kazuyoshi Yanagihara, Shogo Ehata, Masakazu Yashiro, Kohei Miyazono, Yo-taro Shirai
Publikováno v:
The American journal of pathology. 179(6)
A relationship exists between defects in bone morphogenetic protein (BMP) signaling and formation of hamartoma and adenoma in the gastric epithelium; however, the role of BMP signaling in the progression of diffuse-type gastric carcinoma remains unkn
Publikováno v:
Cancer Weekly; 4/11/2024, p1148-1148, 1p
Publikováno v:
Laboratory Investigation (00236837); Sep2018, Vol. 98 Issue 9, p1126-1132, 7p
Autor:
Toshifumi Inada, Arora, Sumit
Publikováno v:
Frontiers in Genetics; Aug2014, Vol. 5, p1-11, 11p