Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yo Jun Choi"'
Autor:
Dong Yun Kim, Yu Jin Sub, Hye-Youn Kim, Kyeong Jee Cho, Won Il Choi, Yo Jun Choi, Min Goo Lee, Friedhelm Hildebrandt, Heon Yung Gee
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background LRRC6 is an assembly factor for dynein arms in the cytoplasm of motile ciliated cells, and when mutated, dynein arm components remained in the cytoplasm. Here, we demonstrate the role of LRRC6 in the active nuclear translocation o
Externí odkaz:
https://doaj.org/article/12d278c2f9ae4adf8b677f55832bb75b
Publikováno v:
Organoid, Vol 3 (2023)
Since the first publication on generating kidney-like cell aggregates from pluripotent stem cells, various modifications have been made to develop more complex and detailed kidney structures. In contrast to earlier models that featured nephron-like s
Externí odkaz:
https://doaj.org/article/049748d3ed774a69afc7215e4bb7a20d
Autor:
Seyoung Yu, Yo Jun Choi, John Hoon Rim, Hye-Youn Kim, Nasim Bekheirnia, Sarah Jane Swartz, Hongzheng Dai, Shen Linda Gu, Soyeon Lee, Ryuichi Nishinakamura, Friedhelm Hildebrandt, Mir Reza Bekheirnia, Heon Yung Gee
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionMutations in ADAMTS9 cause nephronophthisis-related ciliopathies (NPHP-RC), which are characterized by multiple developmental defects and kidney diseases. Patients with NPHP-RC usually have normal glomeruli and negligible or no proteinuri
Externí odkaz:
https://doaj.org/article/5de8dedbad1248e986b831e845332ea0
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 4, Pp 594-603 (2020)
Kidney disease: The flaw behind a faulty filter A genetic mutation associated with kidney disease impairs the maturation and migration of cells that filter waste products out of the blood. Tiny tendrils from kidney cells called podocytes establish a
Externí odkaz:
https://doaj.org/article/62ab90a4824f4561abd30d3758ac704e
Autor:
Jung Min Kim, John Hoon Rim, Da Hye Kim, Hye‐Youn Kim, Sung Kyoung Choi, Dong Yun Kim, Yo Jun Choi, Seyoung Yu, Jae Hee Cheon, Heon Yung Gee
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 3, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/612e1c60221d4d428462e9fb006757c6
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 449 (2020)
ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) are a family of multidomain extracellular protease enzymes with 19 members. A growing number of ADAMTS family gene variants have been identified in patients with various heredita
Externí odkaz:
https://doaj.org/article/60e963b3f65644e6ac21ce13fd2f86d4
Autor:
Dong Yun Kim, S K Choi, Hyun-Chul Kim, Heon Yung Gee, Seyoung Yu, John Hoon Rim, Yo Jun Choi, Jae Hee Cheon, Jung Min Kim, Da Hye Kim
Publikováno v:
Journal of Crohn's and Colitis. 15:S236-S238
Background Inflammatory bowel diseases (IBDs), such as ulcerative colitis (UC), are characterized by a disturbance of the normal gut microbiota and contribute to the development of chronic kidney disease (CKD). The incidence of CKD is higher in indiv
Autor:
Yo Jun Choi, Heon Yung Gee, Jae Hee Cheon, Da Hye Kim, Sung Kyoung Choi, Hye Youn Kim, Seyoung Yu, Jung Min Kim, Dong Yun Kim, John Hoon Rim
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 3, Pp n/a-n/a (2021)
Clinical and Translational Medicine
Clinical and Translational Medicine
Publikováno v:
Experimental & Molecular Medicine
Experimental and Molecular Medicine, Vol 52, Iss 4, Pp 594-603 (2020)
Experimental and Molecular Medicine, Vol 52, Iss 4, Pp 594-603 (2020)
PLCE1 encodes phospholipase C epsilon, and its mutations cause recessive nephrotic syndrome. However, the mechanisms by which PLCE1 mutations result in defects associated with glomerular function are not clear. To address this, we investigated the fu
Autor:
John Hoon Rim, Sumeda Nandadasa, Jan Halbritter, Heon Yung Gee, Suneel S. Apte, Friedhelm Hildebrandt, Sidharth Kumar Sethi, Friederike Körber, Richard P. Lifton, Bodo B. Beck, Yo Jun Choi, David Schapiro, Daniela A. Braun, Markus Schueler, Shirlee Shril, Won-Il Choi, Eugen Widmeier
Nephronophthisis-related ciliopathies (NPHP-RCs) are a group of inherited diseases that are associated with defects in primary cilium structure and function. To identify genes mutated in NPHP-RC, we performed homozygosity mapping and whole-exome sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b371a0da5bfc3a6190f226d36385f6
https://europepmc.org/articles/PMC6323550/
https://europepmc.org/articles/PMC6323550/