Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ylva Kaiser"'
Autor:
Andrew J. Kinloch, Ylva Kaiser, Don Wolfgeher, Junting Ai, Anders Eklund, Marcus R. Clark, Johan Grunewald
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Vimentin has been implicated in pulmonary sarcoidosis as a T-cell autoantigen, particularly in the context of HLA-DRB1*03, the Vα2.3/Vβ22 T-cell receptor (TCR), and Löfgren’s syndrome. As vimentin is a known antigenic target in B-cell-mediated a
Externí odkaz:
https://doaj.org/article/7c7944ffee0f4a508af87a99d7fd07f6
Autor:
Ylva Kaiser, Tadepally Lakshmikanth, Yang Chen, Jaromir Mikes, Anders Eklund, Petter Brodin, Adnane Achour, Johan Grunewald
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Sarcoidosis is a granulomatous disorder of unknown etiology, characterized by accumulation of activated CD4+ T cells in the lungs. Disease phenotypes Löfgren’s syndrome (LS) and “non-LS” differ in terms of clinical manifestations, genetic back
Externí odkaz:
https://doaj.org/article/bffe4b36458845ed8ad7b96b3a175c07
Publikováno v:
Seminars in Respiratory and Critical Care Medicine. 38:463-476
Löfgren's syndrome (LS), first described in 1946 by Swedish Professor of Medicine Sven Löfgren, is a clinically distinct phenotype of sarcoidosis. Patients typically experience an acute disease onset, usually with fever, and characteristic symptoms
Autor:
Emma Lindh, Ola Winqvist, Marie Jo Halaby, Saikiran K. Sedimbi, Tracy L. McGaha, Ylva Kaiser, Fredrik Wermeling, Yunying Chen, Mikael C. I. Karlsson, Amanda Duhlin, Rahul Shinde
Publikováno v:
The Journal of Immunology. 197:2618-2626
Autoimmune diseases are characterized by pathogenic immune responses to self-antigens. In systemic lupus erythematosus (SLE), many self-antigens are found in apoptotic cells (ACs), and defects in removal of ACs from the body are linked to a risk for
Publikováno v:
The European respiratory journal. 54(1)
Despite more than a century of research, the causative agent(s) in sarcoidosis, a heterogeneous granulomatous disorder mainly affecting the lungs, remain(s) elusive. Following identification of genetic factors underlying different clinical phenotypes
Autor:
Anders Eklund, Donald Wolfgeher, Junting Ai, Johan Grunewald, Ylva Kaiser, Marcus R. Clark, Andrew J Kinloch
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
Vimentin has been implicated in pulmonary sarcoidosis as a T-cell autoantigen, particularly in the context of HLA-DRB1*03, the Vα2.3/Vβ22 T-cell receptor (TCR), and Lofgren's syndrome. As vimentin is a known antigenic target in B-cell-mediated auto
Autor:
Marlies S. Wijsenbeek, Ylva Kaiser, Mirjam Kool, Jelle R. Miedema, Johan Grunewald, Caroline E. Broos
Publikováno v:
Journal of Autoimmunity, 87, 82-96. Academic Press
Sarcoidosis, a multisystem granulomatous disorder, has historically been classified as Th1-driven disease. However, increasing data demonstrate a key role of Th17-cell plasticity in granuloma formation and maintenance. In Lofgren's syndrome (LS), an
Autor:
Johan Grunewald, Ylva Kaiser, Anna Smed-Sörensen, Rico Lepzien, Susanna Kullberg, Anders Eklund
Publikováno v:
The European respiratory journal. 48(2)
Disease phenotypes of pulmonary sarcoidosis are distinguished by clinical rather than immunological criteria. We aimed to characterise patterns of CD4+ T-cell lineage plasticity underlying the differences in clinical presentation and disease course b
Autor:
Tatiana Sandalova, Remi-Andre Olsen, Kerstin M. Ahlgren, Jan Wahlström, Natalia V. Rivera, Marcus Ronninger, Max Käller, Sverker Lundin, Anders Eklund, M. Ostadkarampour, Britta Lötstedt, Lina Sylwan, Ylva Kaiser, Johan Grunewald, Adnane Achour, Francesco Vezzi
Publikováno v:
The European respiratory journal. 47(3)
In pulmonary sarcoidosis, CD4+ T-cells expressing T-cell receptor Vα2.3 accumulate in the lungs of HLA-DRB1*03+ patients. To investigate T-cell receptor-HLA-DRB1*03 interactions underlying recognition of hitherto unknown antigens, we performed detai
Autor:
Angela M Mitchell, Ylva Kaiser, Michael T Falta, Anders Eklund, Johan Grunewald, Andrew P Fontenot
Publikováno v:
The Journal of Immunology. 198:55.36-55.36
Sarcoidosis is a multisystem disorder that most commonly affects the lungs and involves granuloma formation with the accumulation of CD4+ T cells at sites of disease. Considerable evidence indicates that CD4+ T cells are involved in the initiation an