Construction of a novel six-gene signature to predict tumour response to induction chemotherapy and overall survival in locoregionally advanced laryngeal and hypopharyngeal carcinoma

Autor: Chen Tan, Lingwa Wang, Yifan Yang, Shizhi He, George G. Chen, Jason YK. Chan, Michael CF. Tong, C.A. van Hasselt, Wenbin Xu, Ling Feng, Ru Wang, Jugao Fang

Publikováno v: Genes and Diseases, Vol 11, Iss 3, Pp 101022- (2024)

Externí odkaz: https://doaj.org/article/d42408c51eac4629af4d8ccde9f5c55c

Differential Effects of Estrogen Receptor Alpha and Beta on Endogenous Ligands of Peroxisome Proliferator-Activated Receptor Gamma in Papillary Thyroid Cancer

Autor: Shucai Yang, Zhongqin Gong, Zhimin Liu, Minghui Wei, Lingbin Xue, Alexander C. Vlantis, Yang Zhang, Jason YK. Chan, C Andrew van Hasselt, Xianhai Zeng, Shuqi Qiu, Nelson Tang, Jing Du, Wei Wei, Michael CF Tong, George G. Chen

Publikováno v: Frontiers in Endocrinology, Vol 12 (2021)

PurposeThe inhibition of estrogen receptor alpha (ERα) or the activation of ERβ can inhibit papillary thyroid cancer (PTC), but the precise mechanism is not known. We aimed to explore the role of ERα and ERβ on the production of endogenous peroxi

Externí odkaz: https://doaj.org/article/ecae1b796bb14602b96cc0f5636698c4

A meta-analysis of narrow-band imaging for the diagnosis of primary nasopharyngeal carcinoma [version 1; referees: 2 approved]

Autor: David CM Yeung, Alexander C Vlantis, Eddy WY Wong, Michael CF Tong, Jason YK Chan

Publikováno v: F1000Research, Vol 7 (2018)

Background: Narrow band imaging (NBI), an endoscopic technique featuring an augmented definition of microvasculature and mucosal patterns. NBI is increasingly advocated as a tool to characterize neoplasia and intestinal metaplasia in endoscopic stand

Externí odkaz: https://doaj.org/article/12483dd68ad04d9a80f7f8f07678b9b2

Questionnaire survey on knowledge, attitudes, and behaviour towards viral hepatitis among the Hong Kong public

Autor: Shikha Singh, Grace Lh Wong, Martin C.S. Wong, Carol Yk Chan, Vincent W-S Wong, H.L. Chan

Publikováno v: Hong Kong Medical Journal.

Introduction We aimed to identify gaps in knowledge, attitudes, and behaviours towards viral hepatitis among the Hong Kong public and provide insights to optimise local efforts towards achieving the World Health Organization's viral hepatitis elimina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ff4b8546e77f1e4c39bf7e765623e1
https://doi.org/10.12809/hkmj219463

Reduced lysosomal clearance of autophagosomes promotes survival and colonization of Helicobacter pylori

Autor: Lin, Zhang, Wei, Hu, Chi H, Cho, Francis Kl, Chan, Jun, Yu, J Ross, Fitzgerald, Cynthia Ky, Cheung, Zhan G, Xiao, Jing, Shen, Long F, Li, Ming X, Li, Justin Cy, Wu, Thomas Kw, Ling, Jason Yk, Chan, Ho, Ko, Gary, Tse, Siew C, Ng, Sidney, Yu, Maggie Ht, Wang, Tony, Gin, Hassan, Ashktorab, Duane T, Smoot, Sunny H, Wong, Matthew Tv, Chan, William Kk, Wu

Publikováno v: Zhang, L, Hu, W, Cho, C H, Chan, F K L, Yu, J, Ross Fitzgerald, J, Cheung, C K Y, Xiao, Z G, Shen, J, Li, L F, Li, M X, Wu, J C Y, Ling, T K W, Chan, J Y K, Ho, K, Tse, G, Ng, S C, Yu, S, Wang, M H T, Gin, T, Ashktorab, H, Smoot, D T, Wong, S H, Chan, M T V & Wu, W K K 2018, ' Reduced lysosomal clearance of autophagosomes promotes survival and colonization of Helicobacter pylori ', The Journal of Pathology, vol. 244, no. 4, pp. 432-444 . https://doi.org/10.1002/path.5033

Evasion of autophagy is key for intracellular survival of bacteria in host cells, but its involvement in persistent infection by Helicobacter pylori, a bacterium identified to invade gastric epithelial cells, remains obscure. The aim of this study wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::49b335551016cb1aef5e11fe8c8d5f4b
https://hdl.handle.net/20.500.11820/9dfeff72-872b-4434-ae37-184fc4b0630a