Dorzolamide suppresses PKCδ -TIRAP-p38 MAPK signaling axis to dampen the inflammatory response

Autor: Sajjan Rajpoot, Ashutosh Kumar, Vadim Gaponenko, Teresa LM Thurston, Dolly Mehta, Syed M Faisal, Kam YJ Zhang, Hem C Jha, Gajanan N Darwhekar, Mirza S Baig

Publikováno v: Future Medicinal Chemistry. 15:533-554

Background: Sepsis is a syndrome due to microbial infection causing impaired multiorgan function. Its underlying cause is immune dysfunction and macrophages play an essential role. Methods: TIRAP interaction with PKCδ in macrophage was studied, reve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::653af0bd334d1f7a8c87d74b6d961a7d
https://doi.org/10.4155/fmc-2022-0260

Effects of the combinations of 6 materials on the improvements in contaminant removals from surface water: purification mechanisms and adsorption kinetics

Autor: ZM Zhao, ZF Wang, YJ Zhang, MY Cheng

Publikováno v: IOP Conference Series: Earth and Environmental Science. 398:012007

The study aims to improve the pollution control and eutrophication reduction in surface water by adding various materials and explore corresponding purification mechanisms. Methods: Six materials (H2O2, NaClO, persulfate, polyacrylamide, zeolite, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23bd40d9cafb550c60c7ad1101398c53
https://doi.org/10.1088/1755-1315/398/1/012007

Quality assessment of predicted protein models using energies calculated by the fragment molecular orbital method

Autor: Kam Yj Zhang, Shinichiro Nakamura, Hiroya Nakata, Koji Ogata, David Simoncini

Publikováno v: Molecular Informatics
Molecular Informatics, Wiley-VCH, 2015, 34 (2-3), pp.97--104. ⟨10.1002/minf.201400108⟩
Molecular Informatics, 2015, 34 (2-3), pp.97--104. ⟨10.1002/minf.201400108⟩

International audience; Protein structure prediction directly from sequences is a very challenging problem in computational biology. One of the most successful approaches employs stochastic conformational sampling to search an empirically derived ene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26028b4f5ca44902819b03f36dafeba1
https://hal.archives-ouvertes.fr/hal-03213976

Natural water softening processes by waterfall effects in karst areas

Autor: YJ Zhang, Xing Cheng, David D. Zhang, An Zhu, M. R. Peart

Publikováno v: Desalination. 129:247-259

The reduction of water hardness, which occurs at waterfalls on rivers in karst areas, is considered to be a result of the waterfall effects. These consist of aeration, jet-flow and low-pressure effects. Waterfall effects bring about two physical chan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d08a6acb448f62da102f7a4d6e9a3adb
https://doi.org/10.1016/s0011-9164(00)00065-5

Simvastatin Prevents the Development of Monocrotaline-Induced Pulmonary Hypertension in the Rats through Reduction of Inflammation

Autor: YJ Zhang, CP Liu, G Li, Weijia Zhang, WX Lu

Publikováno v: A106. ROLE OF INFLAMMATION IN PULMONARY VASCULAR REMODELING AND INJURY.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a3c3bd0526f30a220e5293f8e5b512d8
https://doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a2354