Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Yizhou, Dong"'
Autor:
Diana D. Kang, Xucheng Hou, Leiming Wang, Yonger Xue, Haoyuan Li, Yichen Zhong, Siyu Wang, Binbin Deng, David W. McComb, Yizhou Dong
Publikováno v:
Bioactive Materials, Vol 37, Iss , Pp 86-93 (2024)
Since the approval of the lipid nanoparticles (LNP)-mRNA vaccines against the SARS-CoV-2 virus, there has been an increased interest in the delivery of mRNA through LNPs. However, current LNP formulations contain PEG lipids, which can stimulate the g
Externí odkaz:
https://doaj.org/article/e315aae8bfdd4b60a132b0a4411383a8
Autor:
Yonger Xue, Yuebao Zhang, Yichen Zhong, Shi Du, Xucheng Hou, Wenqing Li, Haoyuan Li, Siyu Wang, Chang Wang, Jingyue Yan, Diana D. Kang, Binbin Deng, David W. McComb, Darrell J. Irvine, Ron Weiss, Yizhou Dong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Adipose stem cells (ASCs) have attracted considerable attention as potential therapeutic agents due to their ability to promote tissue regeneration. However, their limited tissue repair capability has posed a challenge in achieving optimal t
Externí odkaz:
https://doaj.org/article/625c5a8ddd304299b6fd4d928fdfa3a5
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 4, Pp 1348-1357 (2023)
Messenger RNA (mRNA) has drawn much attention in the medical field. Through various treatment approaches including protein replacement therapies, gene editing, and cell engineering, mRNA is becoming a potential therapeutic strategy for cancers. Howev
Externí odkaz:
https://doaj.org/article/179df40216524a4c99bad1a4d7416c04
Publikováno v:
BMEMat, Vol 1, Iss 3, Pp n/a-n/a (2023)
Abstract Cell therapy has revolutionized the treatment of various diseases, such as cancers, genetic disorders, and autoimmune diseases. Currently, most cell therapy products rely on ex vivo cell engineering, which requires sophisticated manufacturin
Externí odkaz:
https://doaj.org/article/9d94b900fffd4649b8f0f39f08f7c09f
Publikováno v:
Exploration, Vol 3, Iss 4, Pp n/a-n/a (2023)
Abstract Adoptive cell therapy (ACT) is a rapidly growing anti‐cancer strategy that has shown promise in treating various cancer types. The concept of ACT involves activating patients’ own immune cells ex vivo and then transferring them back to t
Externí odkaz:
https://doaj.org/article/09758395a3b5417ca0ffe36d1ec81b0c
Publikováno v:
Frontiers in Genome Editing, Vol 5 (2023)
Severe respiratory syndrome coronavirus 2 (SARS-CoV-2) and other coronaviruses depend on host factors for the process of viral infection and replication. A better understanding of the dynamic interplay between viral pathogens and host cells, as well
Externí odkaz:
https://doaj.org/article/bca0d61ae269422eafb297fc0c6bd79f
Autor:
Shi Du, Wenqing Li, Yuebao Zhang, Yonger Xue, Xucheng Hou, Jingyue Yan, Jeffrey Cheng, Binbin Deng, David W. McComb, Jennifer Lin, Hong Zeng, Xiaolin Cheng, Darrell J. Irvine, Ron Weiss, Yizhou Dong
Publikováno v:
Advanced Science, Vol 10, Iss 11, Pp n/a-n/a (2023)
Abstract Male infertility caused by genetic mutations is an important type of infertility. Currently, there is no reliable method in the clinic to address this medical need. The emergence of mRNA therapy provides a possible strategy for restoring mut
Externí odkaz:
https://doaj.org/article/9d73ad80650f478b8530e1d5629c2893
Autor:
Wenqing Li, Xinfu Zhang, Chengxiang Zhang, Jingyue Yan, Xucheng Hou, Shi Du, Chunxi Zeng, Weiyu Zhao, Binbin Deng, David W. McComb, Yuebao Zhang, Diana D. Kang, Junan Li, William E. Carson, Yizhou Dong
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Antibodies targeting OX40 or CD137, two T cell costimulatory receptors, have been shown to improve antitumor immunity. Here the authors design a phospholipid-derived nanoparticle to deliver OX40 or CD137 mRNA to T cells in vivo, improving efficacy of
Externí odkaz:
https://doaj.org/article/c560ecaa3fe24937b23b46640aec4f30
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Autor:
Kang, Diana D., Xucheng Hou, Leiming Wang, Yonger Xue, Haoyuan Li, Yichen Zhong, Siyu Wang, Binbin Deng, McComb, David W., Yizhou Dong
Publikováno v:
Bioactive Materials; Jul2024, Vol. 37, p86-93, 8p