Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yizhi Qi"'
Autor:
Karl J. Fisher, Robert Kinsey, Raodoh Mohamath, Tony Phan, Hong Liang, Mark T. Orr, William R. Lykins, Jeffrey A. Guderian, Julie Bakken, David Argilla, Gabi Ramer-Denisoff, Elise Larson, Yizhi Qi, Sandra Sivananthan, Karina Smolyar, Darrick Carter, Christopher J. Paddon, Christopher B. Fox
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-19 (2023)
Abstract Synthetic biology has allowed for the industrial production of supply-limited sesquiterpenoids such as the antimalarial drug artemisinin and β-farnesene. One of the only unmodified animal products used in medicine is squalene, a triterpenoi
Externí odkaz:
https://doaj.org/article/1ba5dda07550439bbc3f99d9fae12512
Autor:
Christopher B. Fox, Yizhi Qi
Publikováno v:
Expert Rev Vaccines
INTRODUCTION: The importance of vaccine thermostability has been robustly discussed in the literature. Nevertheless, the challenge of developing thermostable vaccine adjuvants has sometimes not received appropriate emphasis. Adjuvants comprise an exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d40563fb6ed1d63908edcc0843404c0
https://europepmc.org/articles/PMC8292183/
https://europepmc.org/articles/PMC8292183/
Publikováno v:
Chemical & Biomedical Imaging, Vol 1, Iss 9, Pp 843-851 (2023)
Externí odkaz:
https://doaj.org/article/15eff98c731a48cea4a0413f52de74e3
Autor:
Yizhi Qi, Christopher B. Fox
Publikováno v:
J Chromatogr A
QS-21 is a triterpene glycoside saponin found in the bark of the Chilean soap bark tree Quillaja saponaria. It is a highly potent vaccine adjuvant that is included in two approved vaccines and has shown promise in numerous other vaccine candidates in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e1c5e0788bc63d361ebd1fa6ea1e43
https://doi.org/10.1016/j.chroma.2020.461705
https://doi.org/10.1016/j.chroma.2020.461705
Publikováno v:
Angewandte Chemie. 128:10452-10456
A new and versatile method is described to engineer precisely defined protein/peptide–polymer therapeutics by a modular approach that consists of three steps: (1) fuse a protein/peptide of interest with an elastin–like–polypeptide that enables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d1e6e5db649696ad5fed9d537f7d03
https://doi.org/10.1002/ange.201604661
https://doi.org/10.1002/ange.201604661
Publikováno v:
Evolutionary Applications, Vol 16, Iss 4, Pp 814-823 (2023)
Abstract The ecological effects of mass‐flowering crops on pollinator abundance and species richness of neighbouring habitats are well established, yet the potential evolutionary consequences remain unclear. We studied effects of proximity to a mas
Externí odkaz:
https://doaj.org/article/ae02136be0624d11a5a2ce1d4bfa38d1
Autor:
Yizhi Qi, Ashutosh Chilkoti
Publikováno v:
Current Opinion in Chemical Biology. 28:181-193
In this review, we summarize —from a materials science perspective— the current state of the field of polymer conjugates of peptide and protein drugs, with a focus on polymers that have been developed as alternatives to the current gold standard,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9db078feb48a74fab9a060aed680621
https://doi.org/10.1016/j.cbpa.2015.08.009
https://doi.org/10.1016/j.cbpa.2015.08.009
Autor:
Yizhi, Qi, Antonina, Simakova, Nancy J, Ganson, Xinghai, Li, Kelli M, Luginbuhl, Imran, Özer, Wenge, Liu, Michael S, Hershfield, Krzysztof, Matyjaszewski, Ashutosh, Chilkoti
Publikováno v:
Nature biomedical engineering. 1
The delivery of therapeutic peptides and proteins is often challenged by a short half-life, and thus the need for frequent injections that limit efficacy, reduce patient compliance and increase treatment cost. Here, we demonstrate that a single subcu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::579c87628a1b94ffa6bce62d62508242
https://pubmed.ncbi.nlm.nih.gov/27974661
https://pubmed.ncbi.nlm.nih.gov/27974661
Autor:
Yizhi Qi, Ashutosh Chilkoti
Publikováno v:
Polym. Chem.. 5:266-276
This review covers the development of the in situ growth of polymers from biomolecules, also termed the “grafting from” conjugation methodology. We trace the evolution of this field of research, with an emphasis on recently developed methods to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7c22c0d3439a0917d936ef4b1529d0b
https://doi.org/10.1039/c3py01089a
https://doi.org/10.1039/c3py01089a
Autor:
Ashutosh Chilkoti, Antonina Simakova, Wenge Liu, Yizhi Qi, Michael S. Hershfield, Kelli M. Luginbuhl, Imran Ozer, Nancy J. Ganson, Krzysztof Matyjaszewski, Xinghai Li
Publikováno v:
Nature Biomedical Engineering. 1
The delivery of therapeutic peptides and proteins is often challenged by short half-lives and the consequent need for frequent injections that limit efficacy, reduce patient compliance and increase treatment cost. Here, we demonstrate that a single s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8003939ec38442caf53c2759db98e20f
https://doi.org/10.1038/s41551-016-0002
https://doi.org/10.1038/s41551-016-0002