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Akademický článek

(+)-Dehydrovomifoliol Alleviates Oleic Acid-Induced Lipid Accumulation in HepG2 Cells via the PPARα–FGF21 Pathway

Autor: Yiyuan Xi, Jujia Zheng, Wei Xie, Xiangwei Xu, Namki Cho, Xudong Zhou, Xiaomin Yu

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

An overload of hepatic fatty acids, such as oleic acid is a key trigger of non-alcoholic fatty liver disease (NAFLD). Here, we investigated whether Artemisia frigida, a valuable traditional medicine used to treat various diseases, could mitigate OA-i

Externí odkaz: https://doaj.org/article/58940ecce84449039262013dc40af79d

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Akademický článek

Resveratrol Alleviates Dextran Sulfate Sodium-Induced Acute Ulcerative Colitis in Mice by Mediating PI3K/Akt/VEGFA Pathway

Autor: Fang Zhu, Jujia Zheng, Fang Xu, Yiyuan Xi, Jun Chen, Xiangwei Xu

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Ulcerative colitis (UC) is a chronic inflammatory disease that affects the colon, and its incidence is on the rise worldwide. Resveratrol (RSV), a polyphenolic compound, was recently indicated to exert anti-inflammatory effects on UC. Consequently, t

Externí odkaz: https://doaj.org/article/00cace2b67fa40d7af330468c28b51f8

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Akademický článek

Cembranoids from a Chinese Collection of the Soft Coral Lobophytum crassum

Autor: Min Zhao, Shimiao Cheng, Weiping Yuan, Yiyuan Xi, Xiubao Li, Jianyong Dong, Kexin Huang, Kirk R. Gustafson, Pengcheng Yan

Publikováno v: Marine Drugs, Vol 14, Iss 6, p 111 (2016)

Ten new cembrane-based diterpenes, locrassumins A–G (1–7), (–)-laevigatol B (8), (–)-isosarcophine (9), and (–)-7R,8S-dihydroxydeepoxysarcophytoxide (10), were isolated from a South China Sea collection of the soft coral Lobophytum crassum,

Externí odkaz: https://doaj.org/article/ab6b9b9d2e824c11a2dae5b1df8af08c

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Akademický článek

Tumour-associated and non-tumour-associated bacteria co-abundance groups in colorectal cancer

Autor: Yuxuan Liang, Qingrong Zhang, Jing Yu, Wenyan Hu, Sihua Xu, Yiyuan Xiao, Hui Ding, Jiaming Zhou, Haitao Chen

Publikováno v: BMC Microbiology, Vol 24, Iss 1, Pp 1-11 (2024)

Abstract Background & aims Gut microbiota is closely related to the occurrence and development of colorectal cancer (CRC). However, the differences in bacterial co-abundance groups (CAGs) between tumor tissue (TT) and normal tissue (NT), as well as t

Externí odkaz: https://doaj.org/article/5faa490857974a05977a2059826430f0

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Plumbagin relieves rheumatoid arthritis through nuclear factor kappa-B (NF-κB) pathway

Autor: Chang Shu, Jun Chen, Meiyan Lv, Yiyuan Xi, Jujia Zheng, Xiangwei Xu

Publikováno v: Bioengineered. 13(5)

This study aimed to explore the effects of plumbagin on rheumatoid arthritis (RA) and its mechanism. The RA cell model was simulated following the treatment of interleukin-1β (IL-1β). After the treatment of various concentrations of plumbagin, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b7af4b85f4e35caa67042e54b96049
https://pubmed.ncbi.nlm.nih.gov/35653787

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Akademický článek

Fluorescent probes for sensing peroxynitrite: biological applications

Autor: Yan Yang, Jinting Shang, Yiyuan Xia, Yuran Gui

Publikováno v: Redox Report, Vol 29, Iss 1 (2024)

Peroxynitrite (ONOO-) is a quintessential reactive oxygen species (ROS) and reactive nitrogen species (RNS), renowned for its potent oxidizing and nitrifying capabilities. Under normal physiological conditions, a baseline level of ONOO- is present wi

Externí odkaz: https://doaj.org/article/4646585142d84bc7a13a77b61bfa6c29

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Akademický článek

SARS-CoV-2 Nsp7 plays a role in cognitive dysfunction by impairing synaptic plasticity

Autor: Jiazheng Guo, WeiLing Li, Mengbing Huang, Jialu Qiao, Pin Wan, Yulin Yao, Lirui Ye, Ye Ding, Jianing Wang, Qian Peng, Wei Liu, Yiyuan Xia, Xiji Shu, Binlian Sun

Publikováno v: Frontiers in Neuroscience, Vol 18 (2024)

It has been reported that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can result in long-term neurological symptoms such as cognitive dysfunction, however the specific mechanisms underlying this phenomenon remain unclear. I

Externí odkaz: https://doaj.org/article/20b293cb80454c348f99c3a08e8bc24e

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