Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Yiya Zhang"'
Autor:
He Zhao, Han Zhao, Yan Tang, Mengfan Li, Yisheng Cai, Xin Xiao, Fanping He, Hongwen Huang, Yiya Zhang, Ji Li
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-17 (2024)
Abstract Background Traditional topical drug delivery for treating inflammatory skin diseases suffers from poor skin penetration and long-term side effects. Metal nanoparticles show promising application in topical drug delivery for inflammatory skin
Externí odkaz:
https://doaj.org/article/432754e45a6640a79cd3a365c0a75763
Autor:
Yiya Zhang, Tao Li, Han Zhao, Xin Xiao, Ximin Hu, Ben Wang, Yingxue Huang, Zhinan Yin, Yun Zhong, Yangfan Li, Ji Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Rosacea patients show facial hypersensitivity to stimulus factors (such as heat and capsaicin); however, the underlying mechanism of this hyperresponsiveness remains poorly defined. Here, we show capsaicin stimulation in mice induces exacerb
Externí odkaz:
https://doaj.org/article/62b7b7bba8eb417ca9246c87d26d591d
Autor:
Yun Zhong, Lei Zhou, Yi Guo, Fan Wang, Fanping He, Yufan Cheng, Xin Meng, Hongfu Xie, Yiya Zhang, Ji Li
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 5, Pp n/a-n/a (2024)
Abstract Background Human dermal fibroblasts (HDFs) are essential in the processes of skin ageing and wound healing. However, the underlying mechanism of HDFs in skin healing of the elderly has not been well defined. This study aims to elucidate the
Externí odkaz:
https://doaj.org/article/29e0ab3de3fd4b50b3003bf16ca23f85
Autor:
He Zhao, Han Zhao, Mengfan Li, Yan Tang, Xin Xiao, Yisheng Cai, Fanping He, Hongwen Huang, Yiya Zhang, Ji Li
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103055- (2024)
Nanozymes with superior antioxidant properties offer new hope for treating oxidative stress-related inflammatory skin diseases. However, lacking sufficient catalytic activity or having complex material designs limit the application of current metalli
Externí odkaz:
https://doaj.org/article/850cb08a6e0b435491a0ba63ae408c3f
Autor:
Zhili Deng, Mengting Chen, Zhixiang Zhao, Wenqin Xiao, Tangxiele Liu, Qinqin Peng, Zheng Wu, San Xu, Wei Shi, Dan Jian, Ben Wang, Fangfen Liu, Yan Tang, Yingxue Huang, Yiya Zhang, Qian Wang, Lunquan Sun, Hongfu Xie, Guohong Zhang, Ji Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Rosacea is a chronic inflammatory skin disorder with high incidence rate. Although genetic predisposition to rosacea is suggested by existing evidence, the genetic basis remains largely unknown. Here we present the integrated results of whol
Externí odkaz:
https://doaj.org/article/02806b4507eb41b3a56a9c267149c09d
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background The role of M0 macrophages and their related genes in the prognosis of hepatocellular carcinoma (HCC) remains poorly characterized. Methods Multidimensional bioinformatic methods were used to construct a risk score model using M0
Externí odkaz:
https://doaj.org/article/b701365d5f9d49278f360f00b8afce62
Autor:
Lei Zhou, Yun Zhong, Yaling Wang, Zhili Deng, Yingxue Huang, Qian Wang, Hongfu Xie, Yiya Zhang, Ji Li
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Rosacea is a common facial skin inflammatory disease featured by hyperactivation of mTORC1 signaling in the epidermis. Due to unclear pathogenesis, the effective treatment options for rosacea remain limited.Methods: Weighted gene co-expre
Externí odkaz:
https://doaj.org/article/ec9dcc44094f4004aa490adb93393f20
Autor:
Yiya Zhang, Yangfan Li, Lei Zhou, Xin Yuan, Yaling Wang, Qing Deng, Zhili Deng, San Xu, Qian Wang, Hongfu Xie, Ji Li
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102427- (2022)
Reactive oxygen species (ROS)-activated proinflammatory signals in keratinocytes play a crucial role in the immunoregulation of inflammatory skin diseases, including rosacea and psoriasis. Nav1.8 is a voltage-gated sodium ion channel, and its abnorma
Externí odkaz:
https://doaj.org/article/50784fd9b0a54a2ebff4d842922754ea
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Aging is characterized by the gradual loss of physiological integrity, resulting in impaired function and easier death. This deterioration is a major risk factor for major human pathological diseases, including cancer, diabetes, cardiovas
Externí odkaz:
https://doaj.org/article/b5aaef77dc0f40579ab064006c098847
Autor:
Zhili Deng, Mengting Chen, Yingzi Liu, San Xu, Yuyan Ouyang, Wei Shi, Dan Jian, Ben Wang, Fangfen Liu, Jinmao Li, Qian Shi, Qinqin Peng, Ke Sha, Wenqin Xiao, Tangxiele Liu, Yiya Zhang, Hongbing Zhang, Qian Wang, Lunquan Sun, Hongfu Xie, Ji Li
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 5, Pp 1-20 (2021)
Abstract Rosacea is a chronic inflammatory skin disorder whose pathogenesis is unclear. Here, several lines of evidence were provided to demonstrate that mTORC1 signaling is hyperactivated in the skin, especially in the epidermis, of both rosacea pat
Externí odkaz:
https://doaj.org/article/3ba2bd93a87b4ead84cc1a7f5f5a666d