Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Yixia Zhao"'
Skeletal muscle-secreted DLPC orchestrates systemic energy homeostasis by enhancing adipose browning
Autor:
Xiaodi Hu, Mingwei Sun, Qian Chen, Yixia Zhao, Na Liang, Siyuan Wang, Pengbin Yin, Yuanping Yang, Sin Man Lam, Qianying Zhang, Alimujiang Tudiyusufu, Yingying Gu, Xin Wan, Meihong Chen, Hu Li, Xiaofei Zhang, Guanghou Shui, Suneng Fu, Licheng Zhang, Peifu Tang, Catherine C. L. Wong, Yong Zhang, Dahai Zhu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract MyoD is a skeletal muscle-specifically expressed transcription factor and plays a critical role in regulating myogenesis during muscle development and regeneration. However, whether myofibers-expressed MyoD exerts its metabolic function in r
Externí odkaz:
https://doaj.org/article/7f3ba31c0daa406185f982a83cb5b4c5
Autor:
Yixia Zhao, Zehao Zhang, Yan Zhang, Yuting Huang, Yanfei Chen, Bofei Chen, Weimin Kang, Jingge Ju
Publikováno v:
Membranes, Vol 13, Iss 10, p 807 (2023)
Recently, the multi-level interwoven structured micro/nano fiber membranes with coarse and fine overlaps have attracted lots of attention due to their advantages of high surface roughness, high porosity, good mechanical strength, etc., but their simp
Externí odkaz:
https://doaj.org/article/3e77a48053164b3e8e40fe26b48ee633
Autor:
Qiuming Zeng, Na Tang, Yilei Ma, Hui Guo, Yixia Zhao, Rong Tang, Chengkai Yan, Song Ouyang, Wallace Y. Langdon, Huan Yang, Matthew C. O’Brien, Jian Zhang
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105151- (2022)
Summary: E3 ubiquitin ligase Cbl-b is involved in the maintenance of a balance between immunity and tolerance. Mice lacking Cbl-b are highly susceptible to experimental autoimmune encephalomyelitis (EAE), a Th17-mediated autoimmune disease. However,
Externí odkaz:
https://doaj.org/article/96fd73cc0bc64898b274ed35a49439da
Autor:
Fei Li, Liming Peng, Sisi Bi, Xiangwei Liu, Tianyi Long, Yixia Zhao, Tianlun Yang, Chenglong Zhang
Publikováno v:
BMJ Open, Vol 10, Iss 2 (2020)
ObjectivesTo determine the independent relationship between depressive symptoms and arterial stiffness in the general Chinese population, and to explore possible interactive factors in the relationship.DesignA cross-sectional study.Setting and partic
Externí odkaz:
https://doaj.org/article/97b360a886bf40b48259cc0840bd6541
Autor:
Xiaohua Yu, Yong Zhang, Tingting Li, Zhao Ma, Haixue Jia, Qian Chen, Yixia Zhao, Lili Zhai, Ran Zhong, Changyin Li, Xiaoting Zou, Jiao Meng, Antony K. Chen, Pier Lorenzo Puri, Meihong Chen, Dahai Zhu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Long non-coding RNAs are important regulators of many diverse biological processes. Here the authors describe Linc-RAM, which regulates myogenesis by binding MyoD and promoting the assembly of the MyoD–Baf60c–Brg1 complex at target genes.
Externí odkaz:
https://doaj.org/article/1c57eaf4e6a84d45965f21b426993e40
miR-378 Activates the Pyruvate-PEP Futile Cycle and Enhances Lipolysis to Ameliorate Obesity in Mice
Autor:
Yong Zhang, Changyin Li, Hu Li, Yipeng Song, Yixia Zhao, Lili Zhai, Haixia Wang, Ran Zhong, Huiru Tang, Dahai Zhu
Publikováno v:
EBioMedicine, Vol 5, Iss C, Pp 93-104 (2016)
Obesity has been linked to many health problems, such as diabetes. However, there is no drug that effectively treats obesity. Here, we reveal that miR-378 transgenic mice display reduced fat mass, enhanced lipolysis, and increased energy expenditure.
Externí odkaz:
https://doaj.org/article/0824930539e34f2bbf71106774839b3a
E3 Ubiquitin Ligase Cbl-b Suppresses Proallergic T Cell Development and Allergic Airway Inflammation
Autor:
Guilin Qiao, Haiyan Ying, Yixia Zhao, Yanran Liang, Hui Guo, Huifeng Shen, Zhenping Li, Julian Solway, Enxiang Tao, Y. Jeffrey Chiang, Stanley Lipkowitz, Josef M. Penninger, Wallace Y. Langdon, Jian Zhang
Publikováno v:
Cell Reports, Vol 6, Iss 4, Pp 709-723 (2014)
E3 ubiquitin ligase Cbl-b has emerged as a gatekeeper that controls the activation threshold of the T cell antigen receptor and maintains the balance between tolerance and autoimmunity. Here, we report that the loss of Cbl-b facilitates T helper 2 (T
Externí odkaz:
https://doaj.org/article/47d1fa5e69ba4bec879466f4c8fe9c8f
Autor:
Hui Guo, Guilin Qiao, Haiyan Ying, Zhenping Li, Yixia Zhao, Yanran Liang, Lifen Yang, Stanley Lipkowitz, Josef M. Penninger, Wallace Y. Langdon, Jian Zhang
Publikováno v:
Cell Reports, Vol 1, Iss 5, Pp 472-482 (2012)
E3 ubiquitin ligase Cbl-b plays a crucial role in T cell activation and tolerance induction. However, the molecular mechanism by which Cbl-b inhibits T cell activation remains unclear. Here, we report that Cbl-b does not inhibit PI3K but rather suppr
Externí odkaz:
https://doaj.org/article/16a2de138b5249439783100580902abf
Autor:
Gang Wang, Hongjing Gao, Zirui Yan, Lei Li, Quanxiang Li, Jie Fan, Yixia Zhao, Nanping Deng, Weimin Kang, Bowen Cheng
Publikováno v:
Journal of Colloid and Interface Science. 647:163-173
Publikováno v:
Journal of Materials Chemistry A. 11:2780-2792
This work provides a composite solid electrolyte combining dendritic SPES nanofibers and LaCoO3 nanowires for ASSLIBs. Benefitting from the promotion of electrolytes on rapid ion deposition, the pouch cell possesses excellent cycle performance.