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Akademický článek

Venetoclax with decitabine or azacitidine in the first‐line treatment of acute myeloid leukemia

Autor: Ian M. Bouligny, Graeme Murray, Michael Doyel, Tilak Patel, Josh Boron, Valerie Tran, Juhi Gor, Yiwei Hang, Yanal Alnimer, Kyle Zacholski, Chad Venn, Nolan A. Wages, Steven Grant, Keri R. Maher

Publikováno v: eJHaem, Vol 4, Iss 2, Pp 381-392 (2023)

Abstract Treatment paradigms for acute myeloid leukemia (AML) have evolved at a rapid pace in recent years. The combination of venetoclax with a hypomethylating agent prolonged survival in clinical trials when compared to hypomethylating agent monoth

Externí odkaz: https://doaj.org/article/4cc2b60d1da740f8a15604fb058c1e94

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Akademický článek

Mechanisms regulating the loss of Tregs in HUPO mice that develop spontaneous inflammatory arthritis

Autor: Qi-Quan Huang, Yiwei Hang, Renee Doyle, Qinwen Mao, Deyu Fang, Richard M. Pope

Publikováno v: iScience, Vol 26, Iss 5, Pp 106734- (2023)

Summary: T regulatory cells (Tregs) are a potential therapeutic target in many autoimmune diseases including rheumatoid arthritis (RA). The mechanisms responsible for the maintenance of Tregs in chronic inflammatory conditions such as RA are poorly u

Externí odkaz: https://doaj.org/article/e8297047994749859429bae8fb61939d

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