Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Yiwei, Gao"'
Publikováno v:
Shipin gongye ke-ji, Vol 45, Iss 6, Pp 24-31 (2024)
In this study, taking the amount of anthocyanin extraction as the main index, the extraction process of lyophilized Lycium ruthenicum anthocyanin was optimized by one-way and orthogonal tests, and the purification process of anthocyanin and its degra
Externí odkaz:
https://doaj.org/article/0c26d1c732564eb8aee84d4396004db8
Autor:
Chan Su, Ruihong Zhang, Xiujuan Zhang, Xiaoning Feng, Qiong Wu, Yiwei Gao, Jing Hao, Yu-lan Mu
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Context: It is very necessary to delay ovarian aging and prevent age-related health problems. The active ingredient in Honghua Xiaoyao tablet (HHXYT) has the effects of anti-oxidation, anti-inflammation, immune regulation and so on.Objective: To expl
Externí odkaz:
https://doaj.org/article/5ff84661bc084e2e9bbdd8df67b9fd60
Autor:
Yuhang Wang, Chengcai Pan, Qihao Chen, Qing Xie, Yiwei Gao, Lingli He, Yue Li, Yanli Dong, Xingyu Jiang, Yan Zhao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Salt-overly-sensitive 1 (SOS1) is a unique electroneutral Na+/H+ antiporter at the plasma membrane of higher plants and plays a central role in resisting salt stress. SOS1 is kept in a resting state with basal activity and activated upon pho
Externí odkaz:
https://doaj.org/article/7a5b81916fe74fad8d6f8555820f8061
Autor:
Yiwei Gao, Shuai Xu, Xiaoli Cui, Hao Xu, Yunlong Qiu, Yiqing Wei, Yanli Dong, Boling Zhu, Chao Peng, Shiqi Liu, Xuejun Cai Zhang, Jianyuan Sun, Zhuo Huang, Yan Zhao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
The CaV2.3 channel is involved in synaptic plasticity and neurological disorders. Here, authors resolve the human CaV2.3 structure to explore functional heterogeneity of VSDs and elucidated the closed- and open-state inactivation mechanisms of the ch
Externí odkaz:
https://doaj.org/article/31904ce1f2d8423dbb6f6cc958e2934c
Autor:
Lingli He, Zhuoya Yu, Ze Geng, Zhuo Huang, Changjiang Zhang, Yanli Dong, Yiwei Gao, Yuhang Wang, Qihao Chen, Le Sun, Xinyue Ma, Bo Huang, Xiaoqun Wang, Yan Zhao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
T-type calcium channels are implicated in many diseases. Here, multiple structures of CaV3.3 channel elucidate molecular mechanisms of T-type CaV channels activation at low voltage and interaction with different clinically used channel blockers.
Externí odkaz:
https://doaj.org/article/2c869b74b72d42eebb9bd7d68d55ac63
Autor:
Xiaojing Li, Feng Xu, Hao Xu, Shuli Zhang, Yiwei Gao, Hongwei Zhang, Yanli Dong, Yanchun Zheng, Bei Yang, Jianyuan Sun, Xuejun Cai Zhang, Yan Zhao, Daohua Jiang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
NaV1.3 is involved in neuronal development, hormone secretion and pain perception. Here, the authors elucidate the molecular mechanism for modulation of NaV1.3 by a site-2 neurotoxin bulleyaconitine A and a subtype selective antagonist ICA121431.
Externí odkaz:
https://doaj.org/article/4638d0c72f164f5d8a96ae7095873380
Autor:
Yanli Dong, Yiwei Gao, Alina Ilie, DuSik Kim, Annie Boucher, Bin Li, Xuejun C. Zhang, John Orlowski, Yan Zhao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Sodium/proton exchanger 1 (NHE1) and its obligate binding partner Calcineurin B-homologous protein 1 (CHP1) regulate intracellular pH and volume homeostasis. Structures of the human NHE1-CHP1 complex offer insight into the regulation of NHE1 pH-sensi
Externí odkaz:
https://doaj.org/article/3f4c24b1d2414fd2bb2b6bbd97155253
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Diabetic kidney disease (DKD) is the major reason of chronic kidney disease (CKD)-caused end-stage renal failure (ESRF), and leads to high mortality worldwide. At present, the treatment of DKD is mainly focused on controlling the hyperglycemia, prote
Externí odkaz:
https://doaj.org/article/56aa07c39868478488f8fca59c3f51c0
Autor:
Yanli Dong, Yiwei Gao, Shuai Xu, Yuhang Wang, Zhuoya Yu, Yue Li, Bin Li, Tian Yuan, Bei Yang, Xuejun Cai Zhang, Daohua Jiang, Zhuo Huang, Yan Zhao
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109931- (2021)
Summary: N-type voltage-gated calcium (CaV) channels mediate Ca2+ influx at presynaptic terminals in response to action potentials and play vital roles in synaptogenesis, release of neurotransmitters, and nociceptive transmission. Here, we elucidate
Externí odkaz:
https://doaj.org/article/3f815d9bfcb64a66b3a15ec8b32f971b
Autor:
Yiwei Gao, Junchao Wang, Mingxuan Cao, Luhao Zang, Hao Liu, Matthew M. F. Yuen, Xiaolei Bai, Ying Wang
Publikováno v:
Micromachines, Vol 13, Iss 12, p 2072 (2022)
The effect of the geometric parameters on the flow and heat transfer characteristics of a double-layer U-shape microchannel heat sink (DL-MCHS) for a high-power diode laser was investigated in this work. FLUENT 19.2 based on the finite volume method
Externí odkaz:
https://doaj.org/article/638e91f7c19f4573b0d9b2a30da009db