Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yiu Wing Sunny Cheung"'
Autor:
Sung-Eun Nam, Yiu Wing Sunny Cheung, Thanh Ngoc Nguyen, Michael Gong, Samuel Chan, Michael Lazarou, Calvin K. Yip
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Nam and Cheung et al. describe the structural and biochemical characterization of human autophagy factor EPG5 that functions in autophagosome–lysosome tethering. They show that hEPG5 adopts an extended shepherd’s staff architecture, binds prefere
Externí odkaz:
https://doaj.org/article/ac50183ec2794e35b04eadd21d872781
Publikováno v:
Journal of Biological Chemistry. 299:104059
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e536338c97515a60550adb2b81bc9fe9
https://doi.org/10.1016/j.jbc.2023.104059
https://doi.org/10.1016/j.jbc.2023.104059
Autor:
Thanh Ngoc Nguyen, Calvin K. Yip, Michael Lazarou, Yiu Wing Sunny Cheung, Michael Gong, Samuel Chan, Sung Eun Nam
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Pivotal to the maintenance of cellular homeostasis, macroautophagy (hereafter autophagy) is an evolutionarily conserved degradation system that involves sequestration of cytoplasmic material into the double-membrane autophagosome and targeting of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98918fbcb8543774057903243b7dd6e9
https://doi.org/10.1038/s42003-021-01830-x
https://doi.org/10.1038/s42003-021-01830-x
Assembly principles of the human R2TP chaperone complex reveal the presence of R2T and R2P complexes
Autor:
Yiu Wing Sunny Cheung, Thiago V. Seraphim, Carlos H.I. Ramos, Gavin Young, Júlio César Borges, Lisandra M. Gava, Yu-Qian Mao, Leandro R.S. Barbosa, Daniel R. Southworth, Mohan Babu, Siripat Aluksanasuwan, Visith Thongboonkerd, Carol V. Robinson, Philipp Kukura, Yuliya Gordiyenko, Walid A. Houry, Larissa Höll, Sadhna Phanse, Nardin Nano, Vaibhav Bhandari, Carolina Colleti
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Structure
Universidade de São Paulo (USP)
instacron:USP
Structure
R2TP is a highly conserved chaperone complex formed by two AAA+ ATPases, RUVBL1 and RUVBL2, that associate with PIH1D1 and RPAP3 proteins. R2TP acts in promoting macromolecular complex formation. Here, we establish the principles of R2TP assembly. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48fe23d7fd00311e1248fe2b4e696e04
https://doi.org/10.1016/j.bpj.2021.11.1122
https://doi.org/10.1016/j.bpj.2021.11.1122
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8051, p 8051 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Macroautophagy (also known as autophagy) is a major pathway for selective degradation of misfolded/aggregated proteins and damaged organelles and non-selective degradation of cytoplasmic constituents for the generation of power during nutrient depriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83ed89fece04572104f1733a40d8059
https://doi.org/10.3390/ijms21218051
https://doi.org/10.3390/ijms21218051