Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Yiu Kay Lai"'
Autor:
Iao-Fai Lam, Min Huang, Margaret Dah-Tysr Chang, Pei-Wun Yao, Yu-Ting Chou, Sim-Kun Ng, Ying-Lin Tsai, Yu-Chang Lin, Yun-feng Zhang, Xiao-yuan Yang, Yiu-Kay Lai
Publikováno v:
Chinese Medicine, Vol 12, Iss 1, Pp 1-11 (2017)
Abstract Background Herbochip® technology is a high throughput drug screening platform in a reverse screening manner, in which potential chemical leads in herbal extracts are immobilized and drug target proteins can be used as probes for screening p
Externí odkaz:
https://doaj.org/article/d380e632273549f0b29804c326411236
Autor:
Yiu-Kay Lai, Leu-Wei Lo, Chung-Shi Yang, Chia-Yan Wu, Chia-Hung Lee, Shih-Hsun Cheng, Shu-Pin Sun, I-Ping Huang
Supplementary Figures 1-2 from Enhanced Chemotherapy of Cancer Using pH-Sensitive Mesoporous Silica Nanoparticles to Antagonize P-Glycoprotein–Mediated Drug Resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c6cd4cb80a4cf1d25d0e73df6ad439
https://doi.org/10.1158/1535-7163.22496971
https://doi.org/10.1158/1535-7163.22496971
Autor:
Yiu-Kay Lai, Leu-Wei Lo, Chung-Shi Yang, Chia-Yan Wu, Chia-Hung Lee, Shih-Hsun Cheng, Shu-Pin Sun, I-Ping Huang
Multidrug resistance (MDR) is the major clinical obstacle in the management of cancer by chemotherapy. Overexpression of ATP-dependent efflux transporter P-glycoprotein (PGP) is a key factor contributing to multidrug resistance of cancer cells. The p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd3bc4b00499106ee32e2d2ae223fb18
https://doi.org/10.1158/1535-7163.c.6535450
https://doi.org/10.1158/1535-7163.c.6535450
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 9, Pp 19169-19185 (2013)
Treatment with geldanamycin (GA) leads to an increase in [Ca2+]c and the production of reactive oxygen species (ROS) in rat brain tumor 9L RBT cells. GA-exerted calcium signaling was blocked by BAPTA/AM and EGTA. The effect of GA on [Ca2+]c was signi
Externí odkaz:
https://doaj.org/article/e84bd7fb48ce490f9ffb6acde13d996f
Autor:
Yiu-Kay Lai, Pei-Wun Yao, Yu-Ting Chou, Xiao-yuan Yang, Yun-feng Zhang, Yu-Chang Lin, Iao-Fai Lam, Min Huang, Ying-Lin Tsai, Margaret Dah-Tysr Chang, Sim-Kun Ng
Publikováno v:
Chinese Medicine, Vol 12, Iss 1, Pp 1-11 (2017)
Chinese Medicine
Chinese Medicine
Background Herbochip® technology is a high throughput drug screening platform in a reverse screening manner, in which potential chemical leads in herbal extracts are immobilized and drug target proteins can be used as probes for screening process [B
Molecular profiling of afatinib-resistant non-small cell lung cancer cells in vivo derived from mice
Autor:
Kai-Yen Chang, Yun-Yu Chen, Chieh-Hsin Chen, Chia-Huei Lee, Kai-Chia Yeh, Cheng-Ta Chung, Pai-Jiun Ho, Yiu Kay Lai, Chiung-Tong Chen
Publikováno v:
Pharmacological Research. 161:105183
Non-small-cell lung cancer (NSCLC) is a leading cause of cancer-related death worldwide. NSCLC patients with overexpressed or mutated epidermal growth factor receptor (EGFR) related to disease progression are treated with EGFR-tyrosine kinase inhibit
Autor:
Iao-Fai Lam, Huang, Min, Chang, Margaret, Pei-Wun Yao, Chou, Yu-Ting, Sim-Kun Ng, Tsai, Ying-Lin, Lin, Yu-Chang, Zhang, Yun-Feng, Yang, Xiao-Yuan, Yiu-Kay Lai
Additional file 2. Ethics approval document of Ducklings experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c5fa88ed5f0e7e49e696ef849ad255
Autor:
Shuilong Leng, Gang Lu, Chaowei Liao, Hua Wang, Marie C.M. Lin, Hsiang-Fu Kung, Xiaoai Zhang, Shao-Chun Chen, Yiu-Kay Lai, Yan Fan
Publikováno v:
Acta Biochimica et Biophysica Sinica. 46:6-14
In order to develop more effective therapeutic vaccines against cancers with high-risk human papillomavirus (HPV) infection, it is crucial to enhance the immunogenicity, eliminate the oncogenicity of oncoproteins, and take a combination of E7- and E6
Publikováno v:
Cellular Microbiology. Nov2007, Vol. 9 Issue 11, p2676-2688. 13p. 2 Black and White Photographs, 4 Graphs.
Publikováno v:
International Journal of Molecular Sciences
Volume 14
Issue 9
Pages 19169-19185
International Journal of Molecular Sciences, Vol 14, Iss 9, Pp 19169-19185 (2013)
Volume 14
Issue 9
Pages 19169-19185
International Journal of Molecular Sciences, Vol 14, Iss 9, Pp 19169-19185 (2013)
Treatment with geldanamycin (GA) leads to an increase in [Ca2+]c and the production of reactive oxygen species (ROS) in rat brain tumor 9L RBT cells. GA-exerted calcium signaling was blocked by BAPTA/AM and EGTA. The effect of GA on [Ca2+]c was signi