Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Yitzhak, Koch"'
Autor:
Tsvetanka Stanoeva, Yitzhak Koch, Mati Fridkin, Barbara Rupp, Nurit Ben-Aroya, B. Mester, Tamar Hanoch, Georg Gescheidt, Rony Seger, Vered Lev-Goldman, Lev Weiner
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:6789-6798
We synthesized two carminic acid (7-alpha-d-glucopyranosyl-9,10-dihydro-3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-2-anthracene carboxlic acid, CA)-GnRH conjugates to be used as a model for potential photoactive targeted compounds. CA was conjugated to
Autor:
Frédérique Barbosa, Georg Gescheidt, Izhak Bilkis, Yehuda Mazur, Vincent Péron, Mati Fridkin, Yitzhak Koch, Shai Rahimipour, Lev Weiner
Publikováno v:
Photochemistry and Photobiology. 74:226-236
In an attempt to develop an efficient chemotherapeutic agent targeted at malignant cells that express receptors to gonadotropin releasing hormone (GnRH) we coupled [D-Lys6]GnRH covalently to an emodin derivative, i.e. emodic acid (Emo) to yield [D-Ly
Publikováno v:
European Journal of Biochemistry. 127:647-650
Two hypothalamic peptide hormones, luteinizing hormone-releasing hormone (LHRH) and thyrotropin-releasing hormone (TRH), have been isolated from human milk and bovine colostrum. Acidified methanolic extracts, prepared from human milk, bovine colostru
Autor:
Nasi Cohen, Nurit Ben-Aroya, Yaniv Barda, Yitzhak Koch, Mati Fridkin, Eyal Mishani, Chaim Gilon, Vered Lev
Publikováno v:
Nuclear Medicine and Biology. 31:921-933
Gonadotropin-releasing hormone (GnRH) is a decapeptide secreted to the pituitary where it binds to specific receptors on the gonadotropes to regulate gonadotropic hormones (luteinizing hormone (LH) and follicle-stimulating hormone (FSH)) synthesis an
Autor:
Nurit Ben-Aroya, Susanna Di-Segni, Shai Rahimipour, Yitzhak Koch, Cesare Giordano, Mati Fridkin
Publikováno v:
Journal of peptide science
11 (2005): 45–52. doi:10.1002/psc.596
info:cnr-pdr/source/autori:Di-Segni S.; Giordano C.; Rahimipour S.; Ben-Aroya N.; Koch Y.; Fridkin M./titolo:Beta-sulfonamido gonadotropin-releasing hormone analogs: synthesis and evaluation of several parent hormone properties./doi:10.1002%2Fpsc.596/rivista:Journal of peptide science (Print)/anno:2005/pagina_da:45/pagina_a:52/intervallo_pagine:45–52/volume:11
11 (2005): 45–52. doi:10.1002/psc.596
info:cnr-pdr/source/autori:Di-Segni S.; Giordano C.; Rahimipour S.; Ben-Aroya N.; Koch Y.; Fridkin M./titolo:Beta-sulfonamido gonadotropin-releasing hormone analogs: synthesis and evaluation of several parent hormone properties./doi:10.1002%2Fpsc.596/rivista:Journal of peptide science (Print)/anno:2005/pagina_da:45/pagina_a:52/intervallo_pagine:45–52/volume:11
With the aim of producing long-acting analogs of gonadotropin releasing hormone (GnRH), four analogs, containing -X(6) (aa)psi(CH(2)SO(2)NH)-Leu(7) building unit (X(aa)=Gly, Ala, Val or Phe), and a reduced-size analog [Des-Tyr(5)]-GnRH which includes
Publikováno v:
Nature Medicine. 8:1421-1426
Can T cells be directly activated to de novo gene expression by gonadotropin-releasing hormone-II (GnRH-II), a unique 10-amino-acid neuropeptide conserved through 500 million years of evolution? GnRH-II, which has been identified in mammals, shares 7
Publikováno v:
Journal of Molecular Neuroscience. 18:65-76
Gonadotropin releasing hormone-I (GnRH-I), a decapeptide serves as a key regulator of reproduction. Recently, several groups have identified in the mammalian brain a second form of GnRH, of unknown function, designated GnRH-II. The human neuronal med
Transcriptional Regulation of the Human GnRH II Gene Is Mediated by a Putative cAMP Response Element
Publikováno v:
Endocrinology. 142:3483-3492
Human neuronal medulloblastoma cells (TE-671) were recently demonstrated to express the two forms of GnRH (GnRH-I and GnRH-II). We have used this cell line as a model system to demonstrate regulation of the human GnRH-II gene by cAMP. RT-PCR and Sout
Publikováno v:
Endocrinology. 142:830-837
GnRH-I serves as the neuropeptide that regulates mammalian reproduction. Recently, several groups have identified in the brain of rodents, monkeys, and humans a second isoform of GnRH (GnRH-II) whose structure is 70% identical to that of GnRH-I. In t
Publikováno v:
Molecular Pharmacology. 57:718-724
In the course of our studies toward the development of novel analogs of the decapeptide gonadotropin releasing hormone (GnRH), we have examined a hexapeptide that is an antagonist of endothelin (ET). It was found that this peptide, Ac-D-Trp-Leu-Asp-I