Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Yiting Guan"'
Autor:
Guoliang Lyu, Yiting Guan, Chao Zhang, Le Zong, Lei Sun, Xiaoke Huang, Li Huang, Lijun Zhang, Xiao-Li Tian, Zhongjun Zhou, Wei Tao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Cellular senescence is associated with epigenetic remodeling. Here, the authors report that TGF-β signaling promotes miR-29 mediated loss of H4K20me3 thus accelerating senescence.
Externí odkaz:
https://doaj.org/article/3fc4fb45806142b6abbf012e462c3364
Autor:
Guoliang Lyu, Chao Zhang, Te Ling, Rui Liu, Le Zong, Yiting Guan, Xiaoke Huang, Lei Sun, Lijun Zhang, Cheng Li, Yu Nie, Wei Tao
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background Congenital heart disease (CHD) is the leading non-infectious cause of death in infants. Monozygotic (MZ) twins share nearly all of their genetic variants before and after birth. Nevertheless, MZ twins are sometimes discordant for
Externí odkaz:
https://doaj.org/article/42509c6813f8482892712d02a9baf57d
Autor:
Guoliang Lyu, Yiting Guan, Chao Zhang, Le Zong, Lei Sun, Xiaoke Huang, Li Huang, Lijun Zhang, Xiao-Li Tian, Zhongjun Zhou, Wei Tao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Externí odkaz:
https://doaj.org/article/f02304d3f2124c5cb283b12ae52d2c4d
Publikováno v:
Zhongguo quanke yixue, Vol 25, Iss 27, Pp 3414-3421 (2022)
Background Noninvasive positive-pressure ventilation (NPPV) is the first choice for the treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS) , a common sleep-related breathing disorder. But low patient adherence to NPPV limits its clinical
Externí odkaz:
https://doaj.org/article/d6bdb3cd9b9d46fdb9ba7f7def23c3ed
Autor:
Xuebin Zhang, Fanju Meng, Wencong Lyu, Jianuo He, Ran Wei, Zhehao Du, Chao Zhang, Yiting Guan, Xiaoke Huang, Guoliang Lyu, Xiao-Li Tian, Lijun Zhang, Wei Tao
One of the prominent drivers of cellular senescence and/or aging is epigenetic alteration, through which orchestrated regulation of gene expression is achieved during the processes. Accumulating endeavors have been devoted to identifying histone modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d4503633c7d8efff5f4efcca5b2b828
https://doi.org/10.1101/2023.05.26.542348
https://doi.org/10.1101/2023.05.26.542348
Dramatic alterations in epigenetic landscapes are known to impact genome accessibility and transcription. Extensive evidence demonstrates that senescent cells undergo significant changes in chromatin structure; however, the mechanisms underlying the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7943b7b29a54f52059a54219320016d3
https://doi.org/10.21203/rs.3.rs-2917877/v1
https://doi.org/10.21203/rs.3.rs-2917877/v1
Autor:
Wei Tao, Lijun Zhang, Xiaoke Huang, Tenghan Zhuang, Guoliang Lyu, Xuebin Zhang, Yiting Guan, Chen Zhang, Lumeng Jia, Cheng Li, Chao Zhang
Publikováno v:
Nucleic Acids Research
The three-dimensional configuration of the chromatin architecture is known to be crucial for alterations in the transcriptional network; however, the underlying mechanisms of epigenetic control of senescence-related gene expression by modulating the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1af4b6a39fdfa21383e6d074ec0345
https://doi.org/10.1093/nar/gkaa858
https://doi.org/10.1093/nar/gkaa858
Autor:
Lijun Zhang, Xuebin Zhang, Wei Tao, Xiaoke Huang, Yiting Guan, Xiao-Li Tian, Chao Zhang, Li Huang
Publikováno v:
Aging Cell
Chromatin organization and transcriptional profiles undergo tremendous reordering during senescence. However, uncovering the regulatory mechanisms between chromatin reconstruction and gene expression in senescence has been elusive. Here, we depicted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e921a345e1cafc32cfe4a3e7db29a68
https://pubmed.ncbi.nlm.nih.gov/33539668
https://pubmed.ncbi.nlm.nih.gov/33539668
Chromatin architecture and gene expression profile undergo tremendous reestablishment during senescence. However, the regulatory mechanism between chromatin reconstruction and gene expression in senescence remain elusive. The chromatin accessibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c73ea320feecb48078e3f46cdc88075
https://doi.org/10.1101/2020.08.13.249458
https://doi.org/10.1101/2020.08.13.249458
Autor:
Lei Sun, Li Huang, Le Zong, Wei Tao, Zhongjun Zhou, Guoliang Lyu, Xiao-Li Tian, Xiaoke Huang, Chao Zhang, Lijun Zhang, Yiting Guan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
Cellular senescence is a well-orchestrated programmed process involved in age-related pathologies, tumor suppression and embryonic development. TGF-β/Smad is one of the predominant pathways that regulate damage-induced and developmentally programmed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fbca88fc5b3bf48f90359119674e00
https://doaj.org/article/3fc4fb45806142b6abbf012e462c3364
https://doaj.org/article/3fc4fb45806142b6abbf012e462c3364