Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yiti Zhang"'
Autor:
Mingri Zhao, Junling Wang, Miao Liu, Yaoyao Xu, Jiali Huang, Yiti Zhang, Jianfeng He, Ao Gu, Mujun Liu, Xionghao Liu
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1693 (2024)
Mutations in the C-terminal of KIF1A (Kinesin family member 1A) may lead to amyotrophic lateral sclerosis (ALS) through unknown mechanisms that are not yet understood. Using iPSC reprogramming technology and motor neuron differentiation techniques, w
Externí odkaz:
https://doaj.org/article/88d229281d8c40a4945e2357409ab11f
Autor:
Min Liu, Yu Zhang, Jianfeng He, Wanxi Liu, Zhexuan Li, Yiti Zhang, Ao Gu, Mingri Zhao, Mujun Liu, Xionghao Liu
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 591 (2024)
Small extracellular vesicles (sEVs) have emerged as promising therapeutic agents and drug delivery vehicles. Targeted modification of sEVs and their contents using genetic modification strategies is one of the most popular methods. This study investi
Externí odkaz:
https://doaj.org/article/d5117165cc084bc782402675adb8cf34
Autor:
Yiti Zhang, Baitao Zeng, Ao Gu, Qinyu Kang, Mingri Zhao, Guangnan Peng, Miaojin Zhou, Wanxi Liu, Min Liu, Lingjie Ding, Desheng Liang, Xionghao Liu, Mujun Liu
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11333 (2022)
Ubiquilin-2 (UBQLN2) mutations lead to familial amyotrophic lateral sclerosis (FALS)/and frontotemporal dementia (FTLD) through unknown mechanisms. The combination of iPSC technology and CRISPR-mediated genome editing technology can generate an iPSC-
Externí odkaz:
https://doaj.org/article/bf7e2a773c7d40f99ce365a7b1850b4f
Autor:
Yan Chen, Desheng Liang, Licong Cai, Hongyan Niu, Guangnan Peng, Xionghao Liu, Miaojin Zhou, Yiti Zhang, Ao Gu, Mujun Liu, Linlin Chen, Jie Liu
Publikováno v:
CNS Neuroscience & Therapeutics
Aims The ubiquilin‐like protein ubiquilin 2 (UBQLN2) is associated with amyotrophic lateral sclerosis and frontotemporal degeneration (ALS/FTD). The biological function of UBQLN2 has previously been shown to be related to stress granules (SGs). In
Autor:
Desheng Liang, Rou Xiao, Bo Liu, Xionghao Liu, Lingqian Wu, Jiasun Su, Yiti Zhang, Baitao Zeng, Ao Gu, Zhiqing Hu, Fei Shen, Miaojin Zhou
Publikováno v:
Biochemical and Biophysical Research Communications. 545:40-45
Duchenne muscular dystrophy (DMD), the most common lethal muscular disorder, affects 1 in 5000 male births. It is caused by mutations in the X-linked dystrophin gene (DMD), and there is no effective treatment currently. Gene addition is a promising s