Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yit Wooi Goh"'
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-16 (2020)
Abstract Background Oncrasin-1 is a small molecule which was identified from a screen of KRAS mutant cancer cells and has shown specificity for KRAS mutant cell killing. We aimed to develop a radiolabelled form of Oncrasin-1 to enable in-vivo imaging
Externí odkaz:
https://doaj.org/article/04b4395c3b2146e187c0abaf413b4ac3
Autor:
Christian W. Wichmann, Yit Wooi Goh, Adam C. Parslow, Angela Rigopoulos, Nancy Guo, Andrew M. Scott, Uwe Ackermann, Jonathan M. White
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-20 (2020)
Abstract Background Targeted therapy of HER2 positive breast cancer has led to clinical success in some cases with primary and secondary resistance being major obstacles. Due to the substantial involvement of mTOR kinase in cell growth and proliferat
Externí odkaz:
https://doaj.org/article/46ec3ba522d9491aa0fbc6b52e05ab56
Autor:
Wanping Geng, Christian Wichmann, Yit Wooi Goh, Angela Rigopoulos, Diana Cao, Linghui Li, Hui K Gan, Yan Lan, Nhi Huynh, Fiona Scott, Andrew M. Scott, Alexander Franklin McDonald, Anup Zutshi, Zhanqi Liu, Sylvia J. Gong, Nancy Guo, Uwe Ackermann, Ingrid Burvenich, Graeme O'Keefe
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 48:3075-3088
Τhis study aimed to optimize the 89Zr-radiolabelling of bintrafusp alfa investigational drug product and controls, and perform the in vitro and in vivo characterization of 89Zr-Df-bintrafusp alfa and 89Zr-Df-control radioconjugates. Bintrafusp alfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b05231523021590b3963635bb631ad8
https://doi.org/10.1007/s00259-021-05251-0
https://doi.org/10.1007/s00259-021-05251-0
Synthesis and fluorine-18 radiolabeling of a phospholipid as a PET imaging agent for prostate cancer
Autor:
Margaret M. Centenera, Lisa M. Butler, Andrew J. Hoy, Johannes V. Swinnen, Jonathan M. White, Ganesh V. Raj, Uwe Ackermann, Yit Wooi Goh, Jonas Dehairs, Ingrid Burvenich, Kim H. Kwan, Andrew M. Scott, Angela Rigopoulos
Publikováno v:
Nucl Med Biol
INTRODUCTION: Altered lipid metabolism and subsequent changes in cellular lipid composition have been observed in prostate cancer cells, are associated with poor clinical outcome, and are promising targets for metabolic therapies. This study reports
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03036f38efdceae27a6ab86c5c9a563f
https://doi.org/10.1016/j.nucmedbio.2020.11.007
https://doi.org/10.1016/j.nucmedbio.2020.11.007
Autor:
Ingrid Julienne Georgette, Burvenich, Yit Wooi, Goh, Nancy, Guo, Hui Kong, Gan, Angela, Rigopoulos, Diana, Cao, Zhanqi, Liu, Uwe, Ackermann, Christian Werner, Wichmann, Alexander Franklin, McDonald, Nhi, Huynh, Graeme Joseph, O'Keefe, Sylvia Jie, Gong, Fiona Elizabeth, Scott, Linghui, Li, Wanping, Geng, Anup, Zutshi, Yan, Lan, Andrew Mark, Scott
Publikováno v:
European journal of nuclear medicine and molecular imaging. 48(10)
Τhis study aimed to optimize theBintrafusp alfa (anti-PD-L1 human IgG1 antibody fused to TGF-β receptor II (TGF-βRII), avelumab (anti-PD-L1 human IgG1 control antibody), isotype control (mutated inactive anti-PD-L1 IgG1 control antibody), and trap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa1fe6362e079eb1d56756ea2c08ef25
https://pubmed.ncbi.nlm.nih.gov/33608805
https://pubmed.ncbi.nlm.nih.gov/33608805
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-16 (2020)
EJNMMI Radiopharmacy and Chemistry
EJNMMI Radiopharmacy and Chemistry
Background Oncrasin-1 is a small molecule which was identified from a screen of KRAS mutant cancer cells and has shown specificity for KRAS mutant cell killing. We aimed to develop a radiolabelled form of Oncrasin-1 to enable in-vivo imaging of mutan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31cfc467f6bbb237a8e8bd1a3958a62d
Additional file 1. Supplementary Data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529a5aae02104c0983015915387e6af0
Autor:
Ingrid Burvenich, Yit Wooi Goh, Sagun Parakh, Hui K Gan, Masakatsu Kotsuma, Andrew M. Scott, Zhanqi Liu, Fook-Thean Lee, Giorgio Senaldi, Graeme O'Keefe, Nancy Guo, Henri Tochon-Danguy, Angela Rigopoulos, Kenji Hirotani, Fiona Scott, Sylvia J. Gong
Publikováno v:
Theranostics
B7-H3 is a transmembrane protein widely expressed in a variety of cancers and has been shown to play a role in anti-tumor immunity. This study aims to develop a molecular imaging probe to identify B7-H3 expression in tumors and to develop 89Zr-DS-557
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84849fe817cce4b5ad97b8d3bf4a8d2b
https://doi.org/10.7150/thno.25575
https://doi.org/10.7150/thno.25575
Autor:
Christian W, Wichmann, Yit Wooi, Goh, Adam C, Parslow, Angela, Rigopoulos, Nancy, Guo, Andrew M, Scott, Uwe, Ackermann, Jonathan M, White
Publikováno v:
EJNMMI Radiopharmacy and Chemistry
Background Targeted therapy of HER2 positive breast cancer has led to clinical success in some cases with primary and secondary resistance being major obstacles. Due to the substantial involvement of mTOR kinase in cell growth and proliferation pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50d9861b3e64f007d64dd488c595cce7
https://pubmed.ncbi.nlm.nih.gov/31974638
https://pubmed.ncbi.nlm.nih.gov/31974638
Publikováno v:
Radiopharmaceutical Chemistry ISBN: 9783319989464
Single-photon emission computerized tomography (SPECT) and positron-emission tomography (PET) imaging are highly sensitive techniques that allow for the non-invasive detection, quantitation, and response monitoring of a broad array of diseases throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a88566de8ec5bc44a755d8b40597ef8d
https://doi.org/10.1007/978-3-319-98947-1_31
https://doi.org/10.1007/978-3-319-98947-1_31