Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Yit Heng Chooi"'
Autor:
Shota Morikawa, Callum Verdonk, Evan John, Leon Lenzo, Nicolau Sbaraini, Chala Turo, Hang Li, David Jiang, Yit-Heng Chooi, Kar-Chun Tan
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract The fungus Parastagonospora nodorum causes septoria nodorum blotch on wheat. The role of the fungal Velvet-family transcription factor VeA in P. nodorum development and virulence was investigated here. Deletion of the P. nodorum VeA ortholog
Externí odkaz:
https://doaj.org/article/0aeb4c41579e4457be7548245f0a1ad1
Autor:
Kar-Chun eTan, Huyen Phan Phan, Kasia eRybak, Evan eJohn, Yit Heng Chooi, Peter Scott Solomon, Richard Peter Oliver
Publikováno v:
Frontiers in Plant Science, Vol 6 (2015)
Necrotrophic diseases of wheat cause major losses in most wheat growing areas of world. Breeding for disease resistance to tan spot and Septoria nodorum blotch is compromised by the universal finding that resistance was quantitative and governed by m
Externí odkaz:
https://doaj.org/article/ad1c8b0f7d224a0788855db7c823d4c9
Autor:
Indra Roux, Clara Woodcraft, Nicolau Sbaraini, Amy Pepper, Emily Wong, Joe Bracegirdle, Yit‐Heng Chooi
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 9, Pp n/a-n/a (2024)
Abstract Episomal AMA1‐based plasmids are increasingly used for expressing biosynthetic pathways and CRISPR/Cas systems in filamentous fungi cell factories due to their high transformation efficiency and multicopy nature. However, the gene expressi
Externí odkaz:
https://doaj.org/article/cdedebec53f049b298166d9344959776
Autor:
Matthias van den Belt, Cameron Gilchrist, Thomas J. Booth, Yit-Heng Chooi, Marnix H. Medema, Mohammad Alanjary
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-8 (2023)
Abstract Background Co-localized sets of genes that encode specialized functions are common across microbial genomes and occur in genomes of larger eukaryotes as well. Important examples include Biosynthetic Gene Clusters (BGCs) that produce speciali
Externí odkaz:
https://doaj.org/article/ce3ee01c945f4592902421521f44c479
Publikováno v:
Fungal Biology and Biotechnology, Vol 6, Iss 1, Pp 1-13 (2019)
Abstract Background Viriditoxin is one of the ‘classical’ secondary metabolites produced by fungi and that has antibacterial and other activities; however, the mechanism of its biosynthesis has remained unknown. Results Here, a gene cluster (vdt)
Externí odkaz:
https://doaj.org/article/18d00fb930c04c3295eca20af9a21b64
Autor:
Heather J. Lacey, Rachel Chen, Daniel Vuong, Ernest Lacey, Peter J. Rutledge, Yit-Heng Chooi, Andrew M. Piggott, Thomas J. Booth
Publikováno v:
Organic & Biomolecular Chemistry. 21:2531-2538
The discovery of the resoruclins, new 3,5-dihydroxybenzoic acid containing macrolides for Steptomyces sp. MST-91080, and their putative biosynthetic pathway.
Publikováno v:
Natural Product Reports. 40:158-173
Covering: up to May 2022Fungal genetics has transformed natural product research by enabling the elucidation of cryptic metabolites and biosynthetic steps. The enhanced capability to add, subtract, modulate, and rewrite genes
Autor:
Michael S. Cowled, Hang Li, Cameron L. M. Gilchrist, Ernest Lacey, Yit-Heng Chooi, Andrew M. Piggott
Publikováno v:
Journal of Natural Products. 86:541-549
Autor:
Hui-Yeng Yeannie Yap, Mariano Jordi Muria-Gonzalez, Boon-Hong Kong, Keith A. Stubbs, Chon-Seng Tan, Szu-Ting Ng, Nget-Hong Tan, Peter S. Solomon, Shin-Yee Fung, Yit-Heng Chooi
Publikováno v:
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-13 (2017)
Abstract Background Genome mining facilitated by heterologous systems is an emerging approach to access the chemical diversity encoded in basidiomycete genomes. In this study, three sesquiterpene synthase genes, GME3634, GME3638, and GME9210, which w
Externí odkaz:
https://doaj.org/article/2df9eeb446b5423ea6a87278bdb2dbfd
Autor:
Indra Roux, Yit-Heng Chooi
Publikováno v:
ACS Synthetic Biology. 11:1186-1195
Building strains of filamentous fungi for stable long-term heterologous expression of large biosynthetic pathways is limited by the low transformation efficiency or genetic stability of current methods. Here, we developed a system for targeted chromo