Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Yisong Wan"'
Autor:
Wenling Li, Hideki Nakano, Wei Fan, Yuanyuan Li, Payel Sil, Keiko Nakano, Fei Zhao, Peer W. Karmaus, Sara A. Grimm, Min Shi, Xin Xu, Ryushin Mizuta, Daisuke Kitamura, Yisong Wan, Michael B. Fessler, Donald N. Cook, Igor Shats, Xiaoling Li, Leping Li
Publikováno v:
JCI Insight, Vol 8, Iss 17 (2023)
DNASE1L3, an enzyme highly expressed in DCs, is functionally important for regulating autoimmune responses to self-DNA and chromatin. Deficiency of DNASE1L3 leads to development of autoimmune diseases in both humans and mice. However, despite the wel
Externí odkaz:
https://doaj.org/article/eba649c4683647208269358c9f30e162
Autor:
Nazanin Kiapour, Bing Wu, Yan Wang, Maryamsadat Seyedsadr, Sahil Kapoor, Xin Zhang, Manal Elzoheiry, Ezgi Kasimoglu, Yisong Wan, Silva Markovic-Plese
Publikováno v:
The Journal of Immunology. 209:49-56
The objective of this study is to determine the mechanism of action of anti-CD52 mAb treatment in patients with relapsing-remitting multiple sclerosis (RRMS). Experimental autoimmune encephalomyelitis (EAE), an animal model of the disease, was used t
Autor:
Li Wang, Adil Muneer, Ling Xie, Feng Zhang, Bing Wu, Liu Mei, Erik M. M. Lenarcic, Emerald Hillary Feng, Juan Song, Yan Xiong, Xufen Yu, Charles Wang, Jeanette G. Cook, Yisong Wan, Nathaniel Moorman, Hongjun Song, Jian Jin, Xian Chen
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
The Journal of Immunology. 206:51.14-51.14
The inflammasome comprised of an innate immune receptor/sensor, pro-caspase-1, and a common adaptor molecule, ASC (apoptotic speck-containing protein with a CARD) initiates innate defense and inflammatory response by activating caspase-1 and pyroptot
Autor:
Zengli Guo, Yisong WAN
Publikováno v:
The Journal of Immunology. 206:53.01-53.01
Immunological aging is characterized by chronic nonspecific inflammation, compromised vaccination and declined immune competence, contributing many age-associated diseases. As the central regulator of immune system, whether and how regulatory T (Treg
Autor:
Bing Wu, Yisong Wan
Publikováno v:
The Journal of Immunology. 202:128.13-128.13
Th17 cells that produce the signature cytokine interleukin 17 (IL-17) can be both pathogenic and non-pathogenic. Pathogenic-Th17 (pTh17) cells drive inflammation and immune-pathology, but whether pTh17 cells are a Th17-subset whose generation is unde
Publikováno v:
Frontiers in Immunology; Sep2015, p1-13, 13p
Publikováno v:
The Journal of Immunology. 192:113.8-113.8
Smad-dependent signaling pathway is known to mediate TGF-beta signal in non-lymphoid cells. How this pathway controls T cell function remains poorly understood. In particular, the function of Smad4 (co-Smad) in T cells is perplexing. On the contrary
Publikováno v:
The Journal of Immunology. 190:117.5-117.5
T cells are pivotal to controlling the immune response to fight infection, eradicate tumor and elicit autoimmunity. CD8 T cells are the “cytotoxic” T cells to mediate the killing of target cells. And CD4 T cells differentiate into “helper” T
Autor:
Yisong Wan
Publikováno v:
Journal of Clinical Immunology; Nov2008, Vol. 28 Issue 6, p647-659, 13p