Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Yisong Qian"'
Autor:
Zhaohui Ruan, Guosheng Cao, Yisong Qian, Longsheng Fu, Jinfang Hu, Tiantian Xu, Yaoqi Wu, Yanni Lv
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract Background and purpose Cerebral ischemia‒reperfusion injury causes significant harm to human health and is a major contributor to stroke-related deaths worldwide. Current treatments are limited, and new, more effective prevention and treat
Externí odkaz:
https://doaj.org/article/edad2d92f3104c1f828005f4b68c0067
Publikováno v:
Cells, Vol 12, Iss 22, p 2648 (2023)
Endothelial cells are the crucial inner lining of blood vessels, which are pivotal in vascular homeostasis and integrity. However, these cells are perpetually subjected to a myriad of mechanical, chemical, and biological stresses that can compromise
Externí odkaz:
https://doaj.org/article/41d439108db94a099df16e00639f7d74
Autor:
Yisong Qian, Ziwei Wang, Hongru Lin, Tianhua Lei, Zhou Zhou, Weilu Huang, Xuehan Wu, Li Zuo, Jie Wu, Yu Liu, Ling-Fang Wang, Xiao-Hui Guan, Ke-Yu Deng, Mingui Fu, Hong-Bo Xin
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract Endothelial activation plays an essential role in the pathogenesis of sepsis-induced acute lung injury, however, the detailed regulatory mechanisms remain largely unknown. Here, we reported that TRIM47, an E3 ubiquitin ligase of the triparti
Externí odkaz:
https://doaj.org/article/00d141d1317a485091f43f3ebbeaa8b3
Autor:
Yixiong Zhan, Duoduo Zha, Hongru Lin, Xianxian Mao, Lingyi Yang, Houda Huang, Zongnan He, Sheng Zhou, Fei Xu, Yisong Qian, Yu Liu
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1101 (2023)
The structure proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), such as nucleocapsid protein (N protein) and envelop protein (E protein), are considered to be the critical pro-inflammatory factors in coronavirus disease 2019 (
Externí odkaz:
https://doaj.org/article/f919b07c531d401480066746fce572c3
Publikováno v:
Cells, Vol 11, Iss 12, p 1972 (2022)
COVID-19 is a highly infectious respiratory disease caused by a new coronavirus known as SARS-CoV-2. COVID-19 is characterized by progressive respiratory failure resulting from diffuse alveolar damage, inflammatory infiltrates, endotheliitis, and pul
Externí odkaz:
https://doaj.org/article/417b8846415f48319c5542c4465916cb
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Nonmuscle myosin ⅡA, a kind of ATP-dependent molecular motor, binds actin to form the molecular motors of the cell. We found that interfering with nonmuscle myosin heavy chain (NMMHC) ⅡA could affect the exosome release from microglial cells stim
Externí odkaz:
https://doaj.org/article/853484d39d1441b68a0e7bdca21ef0ab
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
17β-Estradiol (E2) is the major estrogen secreted by the premenopausal ovary and shows dual effects on cell apoptosis under pathological conditions. E2 was previously shown to increase CD38 mRNA and protein expression in myometrial smooth muscle, bu
Externí odkaz:
https://doaj.org/article/87c7f6c3b3464381a1af6c1e64505130
Autor:
Yisong Qian, Chuqiao Chen, Leliang Ma, Ziwei Wang, Ling-Fang Wang, Li Zuo, Yaqin Yang, Xiang Huang, Meixiu Jiang, Xiaolei Wang, Huidong Shi, Mingui Fu, Ke-Yu Deng, Hong-Bo Xin
Publikováno v:
Mediators of Inflammation, Vol 2018 (2018)
CD38 was first identified as a lymphocyte-specific antigen and then has been found to be widely expressed in a variety of cell types. The functions of CD38 are involved in numerous biological processes including immune responses. Here, we showed the
Externí odkaz:
https://doaj.org/article/8a56d059d2894866892a31d34b36294f
Publikováno v:
Molecules, Vol 21, Iss 9, p 1248 (2016)
Myocardial ischemic/reperfusion injury results from severe impairment of coronary blood supply and leads to irreversible cell death, with limited therapeutic possibilities. Asiatic acid is a pentacyclic triterpenoid derived from the tropical medicina
Externí odkaz:
https://doaj.org/article/e497de69cf6b4f9a881469bda2f9e34a
Publikováno v:
Molecules, Vol 21, Iss 8, p 1093 (2016)
Glutamate-mediated excitotoxicity is a major cause of ischemic brain damage. MK-801 confers neuroprotection by attenuating the activation of the N-methyl-d-aspartate (NMDA) receptor, but it failed in clinical use due to the short therapeutic window.
Externí odkaz:
https://doaj.org/article/08dd8fed682f4d4db5b44a41ab82cd98