Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Yisheng Lu"'
Autor:
Zhanghong Zhou, E. Tian, Jun Wang, Zhaoqi Guo, Jingyu Chen, Jiaqi Guo, Shiyu Shi, Wandi Xu, Xixi Yu, Caijuan Qiao, Yuejin Zhang, Yisheng Lu, Sulin Zhang
Publikováno v:
Neurobiology of Disease, Vol 202, Iss , Pp 106719- (2024)
The vestibular system is essential for balance and spatial orientation, and its dysfunction can lead to cognitive deficits. This study investigates the effects of unilateral vestibular dysfunction (UVL) on cognitive function and the underlying neurob
Externí odkaz:
https://doaj.org/article/73aa735c739849a8b49511b0840030c6
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24464- (2024)
Glioma is typically characterized by a poor prognosis and is associated with a decline in the quality of life as the disease advances. However, the development of effective therapies for glioma has been inadequate. Caveolin-1 (CAV-1) is a membrane pr
Externí odkaz:
https://doaj.org/article/f48f4c468383496d881d2478477fa1c5
Autor:
Zhaoqi Guo, E Tian, Sen Chen, Jun Wang, Jingyu Chen, Weijia Kong, Debbie C. Crans, Yisheng Lu, Sulin Zhang
Publikováno v:
Antioxidants, Vol 13, Iss 3, p 327 (2024)
Noise-induced hearing loss (NIHL) is a prevalent form of adult hearing impairment, characterized by oxidative damage to auditory sensory hair cells. Although certain dihydropyridines, the L-type calcium channel blockers, exhibit protective properties
Externí odkaz:
https://doaj.org/article/4643e4b34e104d6bb7dd147c687a1717
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
BackgroundThe commissural inhibitory system between the bilateral medial vestibular nucleus (MVN) plays a key role in vestibular compensation. Calcium-binding protein parvalbumin (PV) is expressed in MVN GABAergic neurons. Whether these neurons are i
Externí odkaz:
https://doaj.org/article/0cf07ed1834a4bd0a05e624e5c69c52d
Autor:
Jun Wang, E Tian, Yuejin Zhang, Zhaoqi Guo, Jingyu Chen, Weijia Kong, Yisheng Lu, Sulin Zhang
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1637 (2023)
Background: This study aimed to investigate the effects of unilateral labyrinthectomy (UL) on monoamine neurotransmitters in the medial vestibular nucleus (MVN) of rats. Methods: Adult Sprague–Dawley rats were utilized for the vestibular impaired a
Externí odkaz:
https://doaj.org/article/924f210129ac44b889e0c57b3acba620
Autor:
Hong Zhou, Jiayu Zhu, Jie Jia, Wei Xiang, Hualing Peng, Yuejin Zhang, Bo Liu, Yangling Mu, Yisheng Lu
Publikováno v:
Neurobiology of Stress, Vol 21, Iss , Pp 100492- (2022)
The nucleus accumbens (NAc) is a crucial region in the reward circuit and is related to anhedonia, the pivotal symptom of major depression disorder (MDD). Deep brain stimulation (DBS) of NAc has been identified as an effective treatment for severe re
Externí odkaz:
https://doaj.org/article/b439025d8931400ebc820f64234d47ce
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Liver-expressed antimicrobial peptide 2 (LEAP2) is a newly discovered antagonist of the growth hormone secretagogue receptor (GHSR) and is considered the first endogenous peptide that can antagonize the metabolic actions of ghrelin. The effects of gh
Externí odkaz:
https://doaj.org/article/148fa947d81f4e1bab43fcbb52ad92e1
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1298 (2023)
Vestibular compensation is a natural behavioral recovery process following unilateral vestibular injury. Understanding the mechanism can considerably enhance vestibular disorder therapy and advance the adult central nervous system functional plastici
Externí odkaz:
https://doaj.org/article/2adcfd005a464b5597419b944acfe78b
Autor:
Zhuo Chen, Susu Pan, Kaili Yin, Yuejin Zhang, Xiaoman Yuan, Sihan Wang, Shujuan Yang, Qing Shen, Yizhe Tang, Juxue Li, Youjun Wang, Yisheng Lu, Guo Zhang
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109868- (2021)
Summary: Store-operated calcium entry (SOCE) is pivotal in maintaining intracellular Ca2+ level and cell function; however, its role in obesity development remains largely unknown. Here, we show that the stromal interaction molecule 1 (Stim1), an end
Externí odkaz:
https://doaj.org/article/492d58279da74bcf8267e1cfe053bd00
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2759 (2022)
The therapeutic effects of volatile anesthetics on mental diseases, particularly schizophrenia, have gained considerable interest. Although isoflurane is a commonly used volatile anesthetic, there’s no more evidence that it could work on treating s
Externí odkaz:
https://doaj.org/article/62d4652ed9254e77951604f2a55b0a9a