Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yishai Avior"'
Autor:
Yishai Avior, Shiri Ron, Dana Kroitorou, Claudia Albeldas, Vitaly Lerner, Barbara Corneo, Erez Nitzan, Daphna Laifenfeld, Talia Cohen Solal
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Major depressive disorder is highly prevalent worldwide and has been affecting an increasing number of people each year. Current first line antidepressants show merely 37% remission, and physicians are forced to use a trial-and-error approac
Externí odkaz:
https://doaj.org/article/f4282fdbeb024ce39789a5c41a572bd3
Publikováno v:
Stem Cell Reports, Vol 8, Iss 5, Pp 1354-1365 (2017)
Human embryonic stem cells (hESCs) provide a platform for studying human development and understanding mechanisms underlying diseases. Retinoblastoma-1 (RB1) is a key regulator of cell cycling, of which biallelic inactivation initiates retinoblastoma
Externí odkaz:
https://doaj.org/article/bc8015bcb22447a6887f9e97b5fe4e46
Publikováno v:
Stem Cell Reports, Vol 4, Iss 6, Pp 967-974 (2015)
Teratoma formation is the gold standard assay for testing the capacity of human pluripotent stem cells to differentiate into all embryonic germ layers. Although widely used, little effort has been made to transform this qualitative assay into a quant
Externí odkaz:
https://doaj.org/article/ea966f50ce5442288a1d8f5e5b2844d4
Autor:
Vitaly Lerner, Talia Cohen Solal, Dana Kroitorou, Shiri Ron, Barbara Corneo, Yishai Avior, Claudia Albeldas, Erez Nitzan, Daphna Laifenfeld
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Translational Psychiatry
Translational Psychiatry
Major depressive disorder is highly prevalent worldwide and has been affecting an increasing number of people each year. Current first line antidepressants show merely 37% remission, and physicians are forced to use a trial-and-error approach when ch
Publikováno v:
Cell Stem Cell. 25:456-461
Human pluripotent stem cells (hPSCs) are known to harbor chromosomal aberrations, affecting their tumorigenic potential. We established a strategy to identify cancer-related point mutations in hPSCs, detecting recurrent mutations in over 20 genes, al
Publikováno v:
Cell stem cell. 28(1)
Human pluripotent stem cells (hPSCs) are known to harbor chromosomal aberrations, affecting their tumorigenic potential. We established a strategy to identify cancer-related point mutations in hPSCs, detecting recurrent mutations in over 20 genes, al
Publikováno v:
Cell stem cell. 28(1)
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 8, Iss 5, Pp 1354-1365 (2017)
Stem Cell Reports, Vol 8, Iss 5, Pp 1354-1365 (2017)
Summary Human embryonic stem cells (hESCs) provide a platform for studying human development and understanding mechanisms underlying diseases. Retinoblastoma-1 (RB1) is a key regulator of cell cycling, of which biallelic inactivation initiates retino
Autor:
Sulagna Ghosh, Seva Kashin, Shila Mekhoubad, Nissim Benvenisty, Kevin Eggan, Genevieve Saphier, Curtis J. Mello, Florian T. Merkle, Maura Charlton, Steven A. McCarroll, Yishai Avior, Nolan Kamitaki, Robert E. Handsaker, Shiran Bar, Jana M. Mitchell, Giulio Genovese, Dusko Ilic
Publikováno v:
Nature. 545:229-233
Human pluripotent stem cells (hPS cells) can self-renew indefinitely, making them an attractive source for regenerative therapies. This expansion potential has been linked with the acquisition of large copy number variants that provide mutated cells
Publikováno v:
Cell stem cell. 25(4)
Human pluripotent stem cells (hPSCs) are known to harbor chromosomal aberrations, affecting their tumorigenic potential. We established a strategy to identify cancer-related point mutations in hPSCs, detecting recurrent mutations in over 20 genes, al