Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yisel M. Cantres-Rosario"'
Autor:
Yisel M. Cantres-Rosario, Valerie Wojna, Rafael Ruiz, Bexaida Diaz, Miriam Matos, Rosa J. Rodriguez-Benitez, Elaine Rodriguez, Richard L. Skolasky, Yamil Gerena
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundHIV-associated neurocognitive disorders (HAND) are one of the HIV-associated comorbidities affecting 20–50% of the people with HIV (PWH) infection. We found that the soluble insulin receptor (sIR) levels in plasma and cerebrospinal fluid
Externí odkaz:
https://doaj.org/article/dc058c7735d84ab68e6038f04c73394e
Autor:
Yisel M Cantres-Rosario, Frances M Acevedo-Mariani, Juliana Pérez-Laspiur, William E Haskins, Marines Plaud, Yadira M Cantres-Rosario, Richard Skolasky, Israel Méndez-Bermúdez, Valerie Wojna, Loyda M Meléndez
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181779 (2017)
HIV-infected monocytes can infiltrate the blood brain barrier as differentiated macrophages to the central nervous system, becoming the primary source of viral and cellular neurotoxins. The final outcome is HIV-associated cognitive impairment (HACI),
Externí odkaz:
https://doaj.org/article/77b82c6b9dc24e4498db647d14ab5e1a
Autor:
Eillen J Rodriguez-Franco, Yisel M Cantres-Rosario, Marines Plaud-Valentin, Rafael Romeu, Yolanda Rodríguez, Richard Skolasky, Viviana Meléndez, Carmen L Cadilla, Loyda M Melendez
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36571 (2012)
Chronic HIV infection leads to the development of cognitive impairments, designated as HIV-associated neurocognitive disorders (HAND). The secretion of soluble neurotoxic factors by HIV-infected macrophages plays a central role in the neuronal dysfun
Externí odkaz:
https://doaj.org/article/37aca7c69f9b4d7298205e94c1687591
Autor:
Luis E Rosas-Vidal, Valeria Lozada-Miranda, Gregory J. Quirk, Alexis Vega-Medina, Loyda M. Meléndez, Yisel M. Cantres-Rosario
Publikováno v:
Neuropsychopharmacology. 43:2636-2644
Brain-derived neurotrophic factor (BDNF) is critical for establishing activity-related neural plasticity. There is increasing interest in the mechanisms of active avoidance and its extinction, but little is known about the role of BDNF in these proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ba908eb2426f7ef79c410a7ae6a35d
https://doi.org/10.1038/s41386-018-0176-8
https://doi.org/10.1038/s41386-018-0176-8
Autor:
Aemil G. Santos-Figueroa, Loyda M. Meléndez, Marines Plaud, Sarah C. Ortiz-Rodríguez, Bianca Cotto, Yisel M. Cantres-Rosario, Dianne Langford, Karla Negron
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
HIV-associated neurocognitive disorders prevail in 20–50 percent of infected individuals. Macrophages transmigrate through the blood brain barrier during HIV-1 infection, triggering neuronal dysfunction. HIV-infected macrophages secrete cathepsin B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041185a96016baedcc192d1df736754e
https://pubmed.ncbi.nlm.nih.gov/31142756
https://pubmed.ncbi.nlm.nih.gov/31142756
Interacting partners of macrophage-secreted cathepsin B contribute to HIV-induced neuronal apoptosis
Autor:
Scott A. Shaffer, Loyda M. Meléndez, John D. Leszyk, Natalia Rodríguez Hernández, Karla Negron, Juliana Perez-Laspiur, Yisel M. Cantres-Rosario
Publikováno v:
AIDS. 29:2081-2092
OBJECTIVE HIV-1 infection of macrophages increases cathepsin B secretion and induces neuronal apoptosis, but the molecular mechanism remains unclear. DESIGN We identified macrophage-secreted cathepsin B protein interactions extracellularly and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24862c8cd1e505830a8176641d18cbc3
https://doi.org/10.1097/qad.0000000000000823
https://doi.org/10.1097/qad.0000000000000823
Autor:
Loyda M. Meléndez, Radhika Adiga, Yisel M. Cantres-Rosario, Frances Zenón, Mariangeline Gonzalez, Dianne Langford, Eillen Rodriguez-Franco
Publikováno v:
Journal of NeuroVirology
HIV-1-infected mononuclear phagocytes release soluble factors that affect the homeostasis in tissue. HIV-1 can prompt metabolic encephalopathy with the addition of neuronal dysfunction and apoptosis. Recently, we reported that HIV-1 enhances the expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3a8b9aff7d36f3e4f0f1941c0cedbd
Publikováno v:
Current HIV Research
Mononuclear phagocytes including monocytes and macrophages, are important defense components of innate immunity, but can be detrimental in HIV-1 infection by serving as the principal reservoirs of virus in brain and triggering a strong immune respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52995cc6546753e0de1210ec072b6033
https://doi.org/10.2174/1570162x12666140526120249
https://doi.org/10.2174/1570162x12666140526120249
Autor:
Maria Elisa Santiago-Gascot, Magdiel Martínez, Emanuel García-Santiago, Jennifer L. Barreto-Estrada, Inelia Otero-Pagán, Juliana Perez-Laspiur, Yisel M. Cantres-Rosario, Abner G. Alemán-Reyes, Loyda M. Meléndez, Cristhian Calo-Guadalupe, Yolanda Rodríguez-Pérez, Freddyson J. Martínez-Rivera, Roxsana N. Ayala-Pagán
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0180409 (2017)
PLoS ONE, Vol 12, Iss 7, p e0180409 (2017)
The abuse of anabolic androgenic steroids (AAS) has been considered a major public health problem during decades. Supraphysiological doses of AAS may lead to a variety of neuroendocrine problems. Precisely, the hypothalamic-pituitary-gonadal (HPG) ax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c91c9ffb50430b793c98194c29181bd1
https://pubmed.ncbi.nlm.nih.gov/28719635
https://pubmed.ncbi.nlm.nih.gov/28719635
Autor:
Loyda M. Meléndez, Yamil Gerena, Valerie Wojna, Richard L. Skolasky, Marines Plaud-Valentin, Yisel M. Cantres-Rosario
Publikováno v:
AIDS (London, England). 27(3)
Objective: HIV-1-associated neurocognitive disorders (HAND) is triggered by immune activation of brain cells and remain prevalent during progressive viral infection despite antiretroviral therapy. Cathepsins and cystatins are lysosomal proteins secre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad42fbe927878010d9c99b18c65384c
https://pubmed.ncbi.nlm.nih.gov/23291538
https://pubmed.ncbi.nlm.nih.gov/23291538