Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Yisang Yoon"'
Autor:
Hakjoo Lee, Tae Jin Lee, Chad A. Galloway, Wenbo Zhi, Wei Xiao, Karen L. de Mesy Bentley, Ashok Sharma, Yong Teng, Hiromi Sesaki, Yisang Yoon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Mitochondria are critical for metabolic homeostasis of the liver, and their dysfunction is a major cause of liver diseases. Optic atrophy 1 (OPA1) is a mitochondrial fusion protein with a role in cristae shaping. Disruption of OPA1 causes mi
Externí odkaz:
https://doaj.org/article/b617f78a85774a2f8dbd285387323e58
Autor:
Sivareddy Kotla, Aijun Zhang, Masaki Imanishi, Kyung Ae Ko, Steven H. Lin, Young Jin Gi, Margie Moczygemba, Sevinj Isgandarova, Keri L. Schadler, Caroline Chung, Sarah A. Milgrom, Jose Banchs, Syed Wamique Yusuf, Diana N. Amaya, Huifang Guo, Tamlyn N. Thomas, Ying H. Shen, Anita Deswal, Joerg Herrmann, Eugenie S. Kleinerman, Mark L. Entman, John P. Cooke, Giovanni Schifitto, Sanjay B. Maggirwar, Elena McBeath, Anisha A. Gupte, Sunil Krishnan, Zarana S. Patel, Yisang Yoon, Jared K. Burks, Keigi Fujiwara, Paul S. Brookes, Nhat-Tu Le, Dale J. Hamilton, Jun-ichi Abe
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102132- (2021)
The incidence of cardiovascular disease (CVD) is higher in cancer survivors than in the general population. Several cancer treatments are recognized as risk factors for CVD, but specific therapies are unavailable. Many cancer treatments activate shar
Externí odkaz:
https://doaj.org/article/e0a94c31b512406eaddff3363f57a4c3
Publikováno v:
Molecular Metabolism, Vol 36, Iss , Pp - (2020)
Objective: Understanding the mechanisms that control brown adipose tissue (BAT) mass and functionality is crucial for our understanding of how the disruption of energy homeostasis leads to obesity. Bernerdinali Seip Congenital Lipodystrophy (BSCL) ty
Externí odkaz:
https://doaj.org/article/8e5932f098914eedb012fd42efea2d3b
Autor:
Shangcheng Xu, Pei Wang, Huiliang Zhang, Guohua Gong, Nicolas Gutierrez Cortes, Weizhong Zhu, Yisang Yoon, Rong Tian, Wang Wang
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
β-adrenergic receptor signaling induces mitochondrial permeability transition pore (mPTP) opening. Here, Xuet al. show that this effect is mediated by phosphorylation of mitochondrial fission protein Drp1 by CamKII, which increases the frequency of
Externí odkaz:
https://doaj.org/article/193253a2af8e40d1889ff8f4ed1f6ac6
Publikováno v:
Antioxidants, Vol 7, Iss 12, p 195 (2018)
Abnormal mitochondrial morphology, especially fragmented mitochondria, and mitochondrial dysfunction are hallmarks of a variety of human diseases including heart failure (HF). Although emerging evidence suggests a link between mitochondrial fragmenta
Externí odkaz:
https://doaj.org/article/fa0dfa4e2350449e9027708dc95be1d6
Autor:
Hakjoo Lee, Yisang Yoon
Publikováno v:
Antioxidants, Vol 7, Iss 12, p 186 (2018)
The maintenance of mitochondrial energetics requires the proper regulation of mitochondrial morphology, and vice versa. Mitochondrial dynamins control mitochondrial morphology by mediating fission and fusion. One of them, optic atrophy 1 (OPA1), is t
Externí odkaz:
https://doaj.org/article/fe27b21725e844f2b2103891236bcb41
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60810 (2013)
Fission and fusion of mitochondrial tubules are the major processes regulating mitochondrial morphology. However, the physiological significance of mitochondrial shape change is poorly understood. Glucose-stimulated insulin secretion (GSIS) in pancre
Externí odkaz:
https://doaj.org/article/ad5a95101fef4932a2c55793618e0afa
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20655 (2011)
Mitochondria in mammals are organized into tubular networks that undergo frequent shape change. Mitochondrial fission and fusion are the main components mediating the mitochondrial shape change. Perturbation of the fission/fusion balance is associate
Externí odkaz:
https://doaj.org/article/d24e687c59354e69b00236373cde77a8
Publikováno v:
Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.)
Purpose: This study compared the extended depth of focus (EDOF) intraocular lens (IOL) (ZXR00; Tecnis Symfony, Johnson & Johnson Vision, Santa Ana, CA, US) to a novel, higher-order aspheric monofocal IOL (ICB00; Tecnis Eyhance, Johnson & Johnson Visi
Autor:
Jianqiu Zou, Wenjuan Wang, Juan Ayala, Masuko Ushio-Fukai, Tohru Fukai, Yisang Yoon, Weiqin Chen, Jie Li, Huabo Su
Publikováno v:
Circulation Research. 131
Neddylation is a reversible post-translational modification that covalently attaches ubiquitin-like protein NEDD8 to target proteins via NEDD8-specific E1-E2-E3 enzymes. Through regulating the function of various cellular proteins, neddylation impact