Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yiren Jian"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
RNA-protein docking is a very challenging area. Here, the authors develop a deep-learning based method, DRPScore, to evaluate RNA-protein complexes. DRPScore is robust and consistently performs better than existing methods on representative testing s
Externí odkaz:
https://doaj.org/article/d2beeb4fda0f4394bfd7c62fce9a5f92
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background It is widely believed that tertiary nucleotide-nucleotide interactions are essential in determining RNA structure and function. Currently, direct coupling analysis (DCA) infers nucleotide contacts in a sequence from its homologous
Externí odkaz:
https://doaj.org/article/7c2638f8d50f4a3d9948291492252d9c
Autor:
Yunjie Zhao, Yiren Jian, Zhichao Liu, Hang Liu, Qin Liu, Chanyou Chen, Zhangyong Li, Lu Wang, H. Howie Huang, Chen Zeng
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract The bulb-type lectins are proteins consist of three sequential beta-sheet subdomains that bind to specific carbohydrates to perform certain biological functions. The active states of most bulb-type lectins are dimeric and it is thus importan
Externí odkaz:
https://doaj.org/article/304dcbb78a7a4df48d8b3f279fdca04a
Publikováno v:
Proceedings of the 28th ACM SIGKDD Conference on Knowledge Discovery and Data Mining.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8782e4e17c853591694000186fa262c
https://doi.org/10.1145/3534678.3539075
https://doi.org/10.1145/3534678.3539075
Autor:
Chen Zeng, Zhichao Liu, Rosemary M. Onjiko, Peter Nemes, Yunjie Zhao, Erika P. Portero, Yiren Jian
Publikováno v:
Anal Chem
Recent developments in high-resolution mass spectrometry (HRMS) technology enabled ultrasensitive detection of proteins, peptides, and metabolites in limited amounts of samples, even single cells. However, extraction of trace-abundance signals from c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ae98631e4fe173f98f6e5b3d17529c
https://doi.org/10.1021/acs.analchem.8b05985
https://doi.org/10.1021/acs.analchem.8b05985
Autor:
Yiren Jian, Chongyang Gao
Training a deep neural model for semantic segmentation requires collecting a large amount of pixel-level labeled data. To alleviate the data scarcity problem presented in the real world, one could utilize synthetic data whose label is easy to obtain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a057ef86393cc0bc4a81d0a8fde59bf4
Autor:
Fatah Kashanchi, Haotian Li, Mohammed Saifuddin, Chen Zeng, Yi Xiao, Yiren Jian, Chenghang Du, Yunjie Zhao, Hao Chen
Publikováno v:
International Journal of Peptide Research and Therapeutics. 25:807-817
Virus mutates quickly and develops drug resistance over time if targeted directly. A possible alternative for drug design is to target cellular proteins that the virus needs. To be viable, the drug ought to inhibit the cellular protein only when boun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a91ae46d9c3826f825592fa96c240c8
https://doi.org/10.1007/s10989-018-9730-9
https://doi.org/10.1007/s10989-018-9730-9
Autor:
Zhichao Liu, Yunjie Zhao, Zhangyong Li, Chen Zeng, Hang Liu, Qin Liu, Chanyou Chen, Yiren Jian, H. Howie Huang, Lu Wang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports
Scientific Reports
The bulb-type lectins are proteins consist of three sequential beta-sheet subdomains that bind to specific carbohydrates to perform certain biological functions. The active states of most bulb-type lectins are dimeric and it is thus important to eluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f295d4ed1e837ca789b994c308d3d701
https://doaj.org/article/304dcbb78a7a4df48d8b3f279fdca04a
https://doaj.org/article/304dcbb78a7a4df48d8b3f279fdca04a
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-12 (2019)
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-12 (2019)
Background It is widely believed that tertiary nucleotide-nucleotide interactions are essential in determining RNA structure and function. Currently, direct coupling analysis (DCA) infers nucleotide contacts in a sequence from its homologous sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3451f2af5dce86ac8fc5c4aab78610a
https://doi.org/10.1186/s12859-019-3099-4
https://doi.org/10.1186/s12859-019-3099-4
Additional file 1. Supplementary material, including all supplementary figures and supplementary tables.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ce29fa015a56bb4be44b97fd31e82b