Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yiqu, Cao"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
FMR1 gene premutation carriers are at risk of developing Fragile X-associated tremor/ataxia syndrome (FXTAS) and Fragile X-associated primary ovarian insufficiency (FXPOI) in adulthood. Currently the development of biomarkers and effective treatments
Externí odkaz:
https://doaj.org/article/f0c32f40804c4708bf799669b39c2232
Autor:
Ha Eun, Kong, Junghwa, Lim, Alexander, Linsalata, Yunhee, Kang, Indranil, Malik, Emily G, Allen, Yiqu, Cao, Lisa, Shubeck, Rich, Johnston, Yanting, Huang, Yanghong, Gu, Xiangxue, Guo, Michael E, Zwick, Zhaohui, Qin, Thomas S, Wingo, Jorge, Juncos, David L, Nelson, Michael P, Epstein, David J, Cutler, Peter K, Todd, Stephanie L, Sherman, Stephen T, Warren, Peng, Jin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(22)
Fragile X–associated tremor/ataxia syndrome (FXTAS) is a debilitating late-onset neurodegenerative disease in premutation carriers of the expanded CGG repeat in FMR1 that presents with a spectrum of neurological manifestations, such as gait ataxia,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41085d2235672607c137326ca7ff6f70
https://pubmed.ncbi.nlm.nih.gov/35617426
https://pubmed.ncbi.nlm.nih.gov/35617426
Autor:
Ha Eun Kong, Junghwa Lim, Alexander Linsalata, Yunhee Kang, Indranil Malik, Emily G. Allen, Yiqu Cao, Lisa Shubeck, Rich Johnston, Yanting Huang, Yanghong Gu, Xiangxue Guo, Michael E. Zwick, Zhaohui Qin, Thomas S. Wingo, Jorge Juncos, David L. Nelson, Michael P. Epstein, David J. Cutler, Peter K. Todd, Stephanie L. Sherman, Stephen T. Warren, Peng Jin
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance Expansion of 55-200 CGG repeats in the 5′ untranslated region of FMR1 predisposes carriers to fragile X–associated tremor/ataxia syndrome (FXTAS), a late-onset neurodegenerative disorder. FXTAS demonstrates incomplete penetrance, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1df20e3bb38f81d058ee328019f3f9f3
https://doi.org/10.1073/pnas.2118124119
https://doi.org/10.1073/pnas.2118124119
Publikováno v:
International Journal of Biological Sciences
Traditional antitumor drugs inhibit the proliferation and metastasis of tumour cells by restraining the replication and expression of DNA. These drugs are usually highly cytotoxic. They kill tumour cells while also cause damage to normal cells at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56feff605e3d563599469d2a285791fb
https://doi.org/10.7150/ijbs.33496
https://doi.org/10.7150/ijbs.33496
Publikováno v:
Frontiers in Molecular Biosciences
FMR1 gene premutation carriers are at risk of developing Fragile X-associated tremor/ataxia syndrome (FXTAS) and Fragile X-associated primary ovarian insufficiency (FXPOI) in adulthood. Currently the development of biomarkers and effective treatments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cf0de493aca8c10af37c3ae7e9d0257
https://pubmed.ncbi.nlm.nih.gov/33195417
https://pubmed.ncbi.nlm.nih.gov/33195417
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1868:359-371
Metabolism is essential to all living organisms that provide cells with energy, regulators, building blocks, enzyme cofactors and signaling molecules, and is in tune with nutritional conditions and the function of cells to make the appropriate develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4723da2a57cad2381ee06e287767baad
https://doi.org/10.1016/j.bbcan.2017.07.002
https://doi.org/10.1016/j.bbcan.2017.07.002