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Akademický článek

CRISPR/Cas9 mediated gene correction ameliorates abnormal phenotypes in spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cells

Publikováno v: Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)

Abstract Spinocerebellar ataxia type 3/Machado–Joseph disease (SCA3/MJD) is a progressive autosomal dominant neurodegenerative disease caused by abnormal CAG repeats in the exon 10 of ATXN3. The accumulation of the mutant ataxin-3 proteins carrying

Externí odkaz: https://doaj.org/article/9315911a81a34e1b9d350b4d37f326db

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Akademický článek

The Natural History of Spinocerebellar Ataxia Type 3 in Mainland China: A 2-Year Cohort Study

Publikováno v: Frontiers in Aging Neuroscience, Vol 14 (2022)

ObjectiveThe natural history of spinocerebellar ataxia type 3 (SCA3) has been reported in several populations and shows heterogeneity in progression rate and affecting factors. However, it remains unexplored in the population of Mainland China. This

Externí odkaz: https://doaj.org/article/1e0d2b56ff784f9ab990e042df4caaca

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Akademický článek

Phylotranscriptomics Shed Light on Intrageneric Relationships and Historical Biogeography of Ceratozamia (Cycadales)

Autor: Sadaf Habib, Yiqing Gong, Shanshan Dong, Anders Lindstrom, Dennis William Stevenson, Hong Wu, Shouzhou Zhang

Publikováno v: Plants, Vol 12, Iss 3, p 478 (2023)

Ceratozamia Brongn. is one of the species-rich genera of Cycadales comprising 38 species that are mainly distributed in Mexico, with a few species reported from neighboring regions. Phylogenetic relationships within the genus need detailed investigat

Externí odkaz: https://doaj.org/article/a239cfaac00d4b799255c238c4e8b604

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Akademický článek

Generation and characterization of expressed sequence tags (ESTs) from coralloid root cDNA library of Cycas debaoensis

Autor: Yunhua Wang, Nan Li, Ting Chen, Yiqing Gong

Publikováno v: Plant Diversity, Vol 40, Iss 5, Pp 245-252 (2018)

A normalized full-length cDNA library was constructed from the coralloid roots of Cycas debaoensis by the DSN (duplex-specific nuclease) normalization method combined with the SMART (Switching Mechanism At 5′ end of the RNA Transcript) technique. T

Externí odkaz: https://doaj.org/article/75824e795ce44d7b99cab2c5f979563e

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Anxiety and depression in spinocerebellar ataxia patients during the COVID-19 pandemic in China: A cross-sectional study

Autor: Kun Xia, Hong Jiang, Mingjie Liu, Yiqing Gong, Rong Qiu, Yuting Shi, Linlin Wan, Chunrong Wang, Yun Peng, Huirong Peng, Zhao Chen, Beisha Tang

Publikováno v: Journal of Clinical Neuroscience. 88:39-46

Coronavirus disease 2019 (COVID-19) is currently a global concern, and the psychological impact cannot be overlooked. Our purpose was to evaluate the anxiety and depression in spinocerebellar ataxia (SCA) patients during the pandemic and to analyse t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac142592f07eaac4aec1aa45bde137cf
https://doi.org/10.1016/j.jocn.2021.03.004

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Geographical isolation rather than convergent evolution explains significant high genetic but low morphological differentiations between two cycad species

Autor: Xiu-Yan Feng, Yiqing Gong, Sinh Khang Nguyen, Tien Hiep Nguyen, Yongbo Liu, Jian Liu, Xun Gong

Exploring the driving forces promoting speciation is a key question in evolutionary biology. Cycas bifida and C. micholitzii are two leaflets dichotomously divided Cycas species that have morphological similarities. Their distribution areas are separ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::43dfd5afbb9afb53ee31111520642cfd
https://doi.org/10.22541/au.166005423.35366013/v1

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