Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Yiqiao Hu"'
Autor:
Zhusheng Huang, Shiqian Huang, Simin Song, Yankui Ding, Hao Zhou, Shaoyin Zhang, Lixing Weng, Ying Zhang, Yiqiao Hu, Ahu Yuan, Yunlu Dai, Zhimin Luo, Lianhui Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The irradiated tumor itself represents an opportunity to establish endogenous in situ vaccines. However, such in situ cancer vaccination (ISCV) triggered by radiation therapy (RT) alone is very weak and hardly elicits systemic anticancer imm
Externí odkaz:
https://doaj.org/article/7e2d1b5160b8403b911d0dae21c7fa9f
Autor:
Zhusheng Huang, Rong Gu, Shiqian Huang, Qian Chen, Jing Yan, Xiaoya Cui, Haojie Jiang, Dan Yao, Chuang Shen, Jiayue Su, Tao Liu, Jinhui Wu, Zhimin Luo, Yiqiao Hu, Ahu Yuan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Radiation-induced in situ tumor vaccination alone is very weak and insufficient to elicit robust antitumor immune responses. In this work, we address this issue by developing chiral vidarabine monophosphate-gadolinium nanowires (aAGd-NWs) th
Externí odkaz:
https://doaj.org/article/250d6bdd916b457a90c2a496427036a4
Autor:
Feng Zhi, Bowen Li, Chuanxia Zhang, Fan Xia, Rong Wang, Weihong Xie, Sihui Cai, Dawei Zhang, Ren Kong, Yiqiao Hu, Yilin Yang, Ya Peng, Jun Cui
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The PI3K/AKT pathway plays an essential role in tumour development. NOD-like receptors (NLRs) regulate innate immunity and are implicated in cancer, but whether they are involved in PI3K/AKT pathway regulation is poorly understood. Here, we
Externí odkaz:
https://doaj.org/article/5364a383799845efa276558c4a64a71b
Autor:
Zijin Feng, Zhijing Hu, Lei Li, Minquan Yu, Yiting Zhang, Peng Jing, Xiangqing Xu, Jinhui Wu, Yiqiao Hu, Xiangyang Xu
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Schizophrenia is a serious psychiatric disorder that significantly affects the quality of life of patients. The objective of this study is to discover a novel antipsychotic candidate with highly antagonistic activity against both serotoni
Externí odkaz:
https://doaj.org/article/a96fac045228435e8ff0883329a4967b
Autor:
Yuxing Liu, Yiqiao Hu, Siyuan Zhang, Yadong Guo, Yaqin Chen, Liangliang Fan, Jieyuan Jin, Rong Xiang
Publikováno v:
Cardiovascular Innovations and Applications, Vol 9, Iss 1, p 966 (2024)
Background: Sudden cardiac death (SCD), unexpected death based on sudden cardiac ejection cessation, accounts for 15–20% of unnatural deaths in developed countries. Primary electrical disorders (PEDs), a group of cardiac rhythm abnormalities withou
Externí odkaz:
https://doaj.org/article/e0d0469e8feb45f998d5adf57d2555a6
Publikováno v:
Microbial Cell, Vol 9, Iss 9, Pp 158-161 (2022)
Cancer immunotherapy, which use the own immune system to attack tumors, are increasingly popular treatments. But, due to the tumor immunosuppressive microenvironment, the antigen presentation in the tumor is limited. Recently, a growing number of peo
Externí odkaz:
https://doaj.org/article/fd7eaf474f22492787a0b09e976fa34f
Autor:
Haoran Wang, Honghui Liu, Yunfei Guo, Wenjing Zai, Xianghui Li, Wei Xiong, Xiaozhi Zhao, Yingfang Yao, Yiqiao Hu, Zhigang Zou, Jinhui Wu
Publikováno v:
Bioactive Materials, Vol 12, Iss , Pp 97-106 (2022)
The ideal photodynamic therapy (PDT) should effectively remove the primary tumor, and produce a stronger immune memory effect to inhibit the tumor recurrence and tumor metastasis. However, limited by the hypoxic and immunosuppressive microenvironment
Externí odkaz:
https://doaj.org/article/585dc43b49164661aeb2beba52e35ec4
Autor:
Yang Liu, Yuchen Wang, Chao Wang, Tiejun Dong, Haiheng Xu, Yunfei Guo, Xiaozhi Zhao, Yiqiao Hu, Jinhui Wu
Publikováno v:
Advanced Science, Vol 9, Iss 31, Pp n/a-n/a (2022)
Abstract The targeted transport of nanomedicines is often impeded by various biological events in the body. Viruses can hijack host cells and utilize intracellular transcription and translation biological events to achieve their replication. Inspired
Externí odkaz:
https://doaj.org/article/644131a96d3c41599a088faf5f08785c
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Chronic kidney disease, a global public health problem, results in kidney damage or a gradual decline in the glomerular filtration rate. Alport syndrome is commonly characterized by chronic glomerulonephritis caused by a structural disord
Externí odkaz:
https://doaj.org/article/101326d2ea2f479cafb57f5031efd56b
Autor:
Muhammad Abbas, Mirza Muhammad Faran Ashraf Baig, Yaliang Zhang, Yu-Shun Yang, Songyu Wu, Yiqiao Hu, Zhong-Chang Wang, Hai-Liang Zhu
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 11, Iss 3, Pp 330-339 (2021)
The study aimed to achieve enhanced targeted cytotoxicity and cell-internalization of cisplatin-loaded deoxyribonucleic acid-nanothread (CPT-DNA-NT), mediated by scavenger receptors into HeLa cells. DNA-NT was developed with stiff-topology utilizing
Externí odkaz:
https://doaj.org/article/4868cdc378464b7e8c803231e39d3a40