Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yipei Ding"'
Autor:
Jinghua Lu, Yipei Ding, Wanqiu Zhang, Yuanyuan Qi, Jin Zhou, Naihan Xu, Yaou Zhang, Weidong Xie
Publikováno v:
Cells, Vol 12, Iss 9, p 1238 (2023)
Migration and invasion play crucial roles in the progression of hepatocellular carcinoma (HCC), but the underlying mechanisms are not clear. Analysis of clinical samples indicates that SQSTM1/p62 is highly expressed in HCC and seriously affects the p
Externí odkaz:
https://doaj.org/article/c6fb00c0bec4418c8afca5e93637cd89
Autor:
Pengbo Sun, Yangyang Wang, Yipei Ding, Jingyi Luo, Jin Zhong, Naihan Xu, Yaou Zhang, Weidong Xie
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102521- (2021)
Summary: Lipotoxicity plays an important role in the development of diabetic heart failure (HF). Canagliflozin (CAN), a marketed sodium-glucose co-transporter 2 inhibitor, has significantly beneficial effects on HF. In this study, we evaluated the pr
Externí odkaz:
https://doaj.org/article/1b3b9a48a7754f4a884ad3ee60f69f35
Autor:
Yangyang Wang, Yipei Ding, Pengbo Sun, Wanqiu Zhang, Qilei Xin, Ningchao Wang, Yaoyun Niu, Yang Chen, Jingyi Luo, Jinghua Lu, Jin Zhou, Naihan Xu, Yaou Zhang, Weidong Xie
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 799 (2022)
Lipotoxicity is an important factor in the development and progression of nonalcoholic steatohepatitis. Excessive accumulation of saturated fatty acids can increase the substrates of the mitochondrial electron transport chain in hepatocytes and cause
Externí odkaz:
https://doaj.org/article/74fed802564a44e8a9ed3f3177c49bc2
Autor:
Xiaobing Zhang, Yunfei Song, Yipei Ding, Wei Wang, Ling Liao, Jin Zhong, Pengbo Sun, Fan Lei, Yaou Zhang, Weidong Xie
Publikováno v:
Molecules, Vol 23, Iss 8, p 1894 (2018)
Obesity and nonalcoholic fatty liver disease (NAFLD) are highly prevalent and cause numerous metabolic diseases. However, drugs for the prevention and treatment of obesity and NAFLD remain unavailable. In this study, we investigated the effects of mo
Externí odkaz:
https://doaj.org/article/7fa5a61ff0dd45e3a64ae8a78774a1a9
Publikováno v:
Experimental & Therapeutic Medicine. Feb2021, Vol. 21 Issue 2, p1-10. 10p.
Autor:
Yang Chen, Yaou Zhang, Weidong Xie, Yipei Ding, Jingyi Luo, Yangyang Wang, Naihan Xu, Pengbo Sun, Yaoyun Niu
Publikováno v:
European journal of pharmacology. 907
Dapagliflozin (DAPA), a kind of sodium-glucose cotransporter 2(SGLT2) inhibitor is used to treat diabetes mellitus by inhibiting urine glucose reuptake. Recent clinical outcomes indicate that SGLT2 inhibitors may exert pharmacological activities agai
Publikováno v:
International Immunopharmacology
To date, drugs to attenuate cytokine storm in severe cases of Corona Virus Disease 2019 (COVID-19) are not available. In this study, we investigated the effects of intragastric and atomized administration of canagliflozin (CAN) on cytokine storm in l
BackgroundLipotoxicity plays an important role in the development of diabetic cardiomyopathy and heart failure (HF). Canagliflozin (CAN), a marketed sodium-glucose co-transporter 2 inhibitor, has significant beneficial effects on HF. However, the pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4d4cc29a7a062e7809dff020881b3fc
https://doi.org/10.21203/rs.3.rs-123774/v1
https://doi.org/10.21203/rs.3.rs-123774/v1
Publikováno v:
Experimental and Therapeutic Medicine
Diabetes is an inflammatory disease that induces pancreatic islet dysfunction. However, to the best of our knowledge, the potential underlying molecular mechanisms of this inflammatory process remains unknown. The present study investigated microRNA
Autor:
Naihan Xu, Yaou Zhang, Jin Zhong, Yipei Ding, Chenke Xu, Meijian Liao, Pengbo Sun, Jin Cai, Weidong Xie
Publikováno v:
Biochemical Pharmacology. 175:113856
Cancer easily induces resistance to most chemotherapy drugs. In this study, we investigated the combination cytotoxic and antitumor effects of canagliflozin (CAN) and doxorubicin (DOX) in vitro and in vivo. CAN significantly increased the cytotoxicit